bactob 80mg injection
What is bactob 80mg injection used for?
Alitop 80 Injection (Tobramycin) is used to treat OPHTHAL OTOLOGICALS. It contains Tobramycin (80mg/2ml), which Binds to 30S ribosomal subunit, inhibiting protein synthesis and causing bacteri. Always consult your doctor before use. Take as prescribed.
- Generic Name: Tobramycin
- Manufacturer: Solitaire Pharmacia Pvt Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ bactob 80mg injection Uses & Benefits
Serious Gram-negative bacterial infections (e.g., Pseudomonas aeruginosa); septicemia; complicated urinary tract infections; respiratory infections; intra-abdominal infections; ophthalmic infections (topical).
Off-label uses: Topical for ophthalmic infections; inhalation for cystic fibrosis (off-label in some regions).
๐ Drug Information
| Generic Name(s) | Tobramycin |
| Brand Name | Alitop 80 Injection |
| Manufacturer | Solitaire Pharmacia Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL OTOLOGICALS |
| Action Class | Aminoglycosides |
| Route of Administration | Intravenous or intramuscular injection |
| Storage | Store at 20-25ยฐC; protect from freezing; use within 24 hours after opening. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to 30S ribosomal subunit, inhibiting protein synthesis and causing bacterial cell death.
Mechanism Steps
๐ก How to Take bactob 80mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bactob 80mg injection
โ Common Side Effects
- Nephrotoxicity (increased creatinine)
- Ototoxicity (hearing loss, tinnitus)
- Vestibular toxicity (dizziness, vertigo)
- Nausea
- Vomiting
- Injection site pain
๐จ Serious Side Effects
- Acute renal failure
- Irreversible hearing loss
- Neuromuscular blockade
- Anaphylaxis
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Pseudomembranous colitis
- Hypomagnesemia
- Hypocalcemia
- Peripheral neuropathy
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Neuromuscular blocking agents | Major | Enhanced neuromuscular blockade, respiratory depression |
| Other aminoglycosides | Major | Increased nephrotoxicity and ototoxicity |
| Vancomycin | Major | Increased nephrotoxicity |
| Amphotericin B | Major | Increased nephrotoxicity |
| Cisplatin | Major | Increased nephrotoxicity and ototoxicity |
| Cyclosporine | Major | Increased nephrotoxicity |
| Loop diuretics | Major | Increased ototoxicity |
| Methoxyflurane | Major | Increased nephrotoxicity |
| Penicillins | Moderate | Synergistic antibacterial effect |
| Cephalosporins | Moderate | Possible additive nephrotoxicity |
| NSAIDs | Moderate | Increased risk of nephrotoxicity |
| ACE inhibitors | Moderate | Increased risk of nephrotoxicity |
| Antiemetics | Minor | Possible masking of ototoxicity |
| Antihistamines | Minor | Possible masking of ototoxicity |
๐จ Major Interactions
- Neuromuscular blocking agents
- Other aminoglycosides
- Vancomycin
- Amphotericin B
- Cisplatin
- Cyclosporine
- Loop diuretics
- Methoxyflurane
โก Moderate Interactions
- Penicillins (synergistic)
- Cephalosporins
- NSAIDs
- ACE inhibitors
โน๏ธ Minor Interactions
- Antiemetics
- Antihistamines
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No direct interaction; avoid excessive alcohol due to potential nephrotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to tobramycin or other aminoglycosides; myasthenia gravis; pre-existing severe renal impairment.
๐ Monitoring Parameters
Serum drug levels (peak and trough), renal function (serum creatinine, BUN), audiometry, vestibular function.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution, monitor infant for diarrhea or candidiasis.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination; monitor renal function and hearing.
โฐ Missed Dose
Administer as soon as remembered; if close to next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for bactob 80mg injection
View AllAlternative brands with exact same active ingredient (Tobramycin (80mg/2ml)):
-
Tosana InjectionSanify Healthcare Pvt Ltd โน49.90 4% COSTLIER
-
Tobaprex 80mg InjectionIkon Remedies Pvt Ltd โน58.25 21.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Helpful and effective medicine as per my experience. Always consult a doctor.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.