Danogen 100 Capsule (Danazol 100mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of skin or eyes (jaundice)
- Severe abdominal pain
- Chest pain or difficulty breathing
- Sudden swelling of face, lips, or throat
- Severe headache with vision changes
- Unusual bleeding or bruising
- Decreased urine output
- Voice deepening or hoarseness
If experiencing severe symptoms, call emergency services immediately.
What is benzol 100mg tablet used for?
Danazol 100 mg capsule is a synthetic steroid used to treat endometriosis, fibrocystic breast disease, and hereditary angioedema. It works by suppressing ovulation and reducing endometrial tissue growth. It is contraindicated in pregnancy and requires regular monitoring of liver function.
- Generic Name: Danazol
- Manufacturer: Solitaire Pharmacia Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 benzol 100mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डैनाज़ोल 100 मिलीग्राम कैप्सूल के रूप में उपलब्ध है और इसका उपयोग एंडोमेट्रियोसिस, फाइब्रोसिस्टिक ब्रेस्ट डिजीज और हेरेडिटरी एंजियोएडेमा के इलाज के लिए किया जाता है। यह अंडाशय की कार्यप्रणाली को दबाकर एंडोमेट्रियल टिशू को कम करने में मदद करती है। यह दवा केवल डॉक्टर की सलाह पर ही लेनी चाहिए। गर्भावस्था और स्तनपान के दौरान यह दवा नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँहासे, तैलीय त्वचा, चेहरे पर बाल बढ़ना, वजन बढ़ना, गर्म लहरें, पसीना और मासिक धर्म में बदलाव शामिल हैं। कुछ रोगियों को मतली, सिरदर्द, चक्कर आना या मूड में बदलाव हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें लिवर की समस्या, रक्त के थक्के और एलर्जी प्रतिक्रियाएँ शामिल हो सकती हैं। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल योग्य चिकित्सक के निर्देशानुसार ही लें। निर्धारित खुराक से अधिक न लें। इस दवा को लेते समय गर्भावस्था से बचने के लिए प्रभावी गैर-हार्मोनल गर्भनिरोधक तरीकों का उपयोग करें। शराब का सेवन न करें क्योंकि इससे लिवर की समस्या बढ़ सकती है। इलाज के दौरान लिवर फंक्शन टेस्ट और अन्य जांचें नियमित रूप से कराते रहें। चक्कर आने पर वाहन न चलाएं। इस दवा को बच्चों की पहुंच से दूर रखें।
💊 benzol 100mg tablet Uses & Benefits
[{"condition":"Endometriosis","description":"This medicine is used to treat endometriosis by suppressing ovarian function and causing atrophy of endometrial implants, which helps relieve pelvic pain and reduce lesion size.","evidence":"Well-established"},{"condition":"Fibrocystic breast disease","description":"It is used to relieve breast pain and nodularity associated with fibrocystic breast changes, although it is typically reserved for severe cases.","evidence":"Established"},{"condition":"Hereditary angioedema","description":"This medicine is used for prophylaxis of hereditary angioedema attacks by increasing levels of C1 esterase inhibitor and reducing the frequency and severity of inflammation" class="semantic-link" title="Medicines for swelling">swelling episodes.","evidence":"Well-established"},{"condition":"Hereditary angioedema prophylaxis before surgery","description":"It may be used short-term before surgical or dental procedures to prevent angioedema attacks in patients with hereditary angioedema.","evidence":"Established"}]
Off-label uses: [{"condition":"Immune thrombocytopenia","description":"Danazol has been used off-label to increase platelet counts in some patients with immune thrombocytopenia, but it is not a first-line treatment.","evidence":"Limited"},{"condition":"Autoimmune hemolytic anemia","description":"It has been used off-label in some cases of autoimmune hemolytic anemia, but evidence is limited and it is not standard therapy.","evidence":"Limited"},{"condition":"Hereditary angioedema prophylaxis in children","description":"Use in children is not well established and is generally avoided due to potential effects on growth and development.","evidence":"Limited"}]
Primary treatment for: Endometriosis
Also treats: Fibrocystic breast disease, Hereditary angioedema
📋 Drug Information
| Generic Name(s) | Danazol |
| Brand Name | Benzol |
| Manufacturer | Solitaire Pharmacia Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Androgen- Endometereosis |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Danazol is a synthetic steroid with weak androgenic activity. It works primarily by inhibiting the release of follicle-stimulating hormone and luteinizing hormone from the pituitary gland, which reduces ovarian stimulation and leads to suppression of ovulation and atrophy of endometrial tissue. In hereditary angioedema, danazol increases the hepatic synthesis of C1 esterase inhibitor, which helps prevent angioedema attacks. It also has some anti-gonadotropic and anti-estrogenic effects.
Mechanism Steps
💡 How to Take benzol 100mg tablet
Strength: Danazol 100 mg immediate-release capsule.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine varies depending on the indication. For endometriosis, the typical dose is 200 to 800 mg per day in divided doses. For fibrocystic breast disease, the dose is 100 to 400 mg per day. For hereditary angioedema prophylaxis, the dose is 200 to 600 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Dose should be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Dose adjustment may be needed in patients with renal impairment. Consult a qualified clinician for individualized dosing. |
| Hepatic Impairment | This medicine is contraindicated in patients with severe hepatic impairment. Dose adjustment may be needed in mild to moderate hepatic impairment. Consult a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose is 800 mg, but it must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of benzol 100mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Carbamazepine | Major | |
| Cyclosporine | Major | |
| Statins | Major | |
| Tacrolimus | Moderate | |
| Phenytoin | Moderate | |
| Oral hypoglycemics | Moderate | |
| Alcohol | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin
- Carbamazepine
- Cyclosporine
- Statins
⚡ Moderate Interactions
- Tacrolimus
- Phenytoin
- Oral hypoglycemics
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase the risk of liver toxicity and may worsen side effects such as dizziness and mood changes.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy or suspected pregnancy.","Breastfeeding.","Undiagnosed abnormal genital bleeding.","Active liver disease or history of cholestatic jaundice.","Known or suspected androgen-dependent tumors.","Severe cardiac, renal, or hepatic impairment.","History of thromboembolic disorders.","Hypersensitivity to danazol or any component of the formulation."]
⚠️ Warnings & Precautions
["This medicine may cause fetal harm. Use effective non-hormonal contraception during treatment.","Do not use in breastfeeding women.","Monitor liver function tests regularly.","May cause fluid retention; use with caution in patients with cardiac or renal impairment.","May increase the risk of thromboembolic events.","May cause virilization symptoms; report voice changes immediately.","May affect blood glucose control in diabetic patients.","Avoid alcohol consumption.","Do not drive or operate machinery if you experience dizziness or vision changes.","Do not share this medicine with others."]
🤱 Lactation Safety
Danazol is excreted in breast milk and may cause harm to the nursing infant. Breastfeeding is not recommended while taking this medicine.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, dizziness, and fluid retention. There is no specific antidote. Treatment is supportive and symptomatic. Seek immediate medical attention if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
This medicine should only be taken exactly as prescribed by a qualified clinician. Do not exceed the recommended dose or duration of treatment. Use effective non-hormonal contraception while taking this medicine, as it can harm a developing fetus. Avoid alcohol consumption, as it may increase the risk of liver problems. Regular monitoring of liver function tests, blood counts, and lipid profile is essential during treatment. Inform your doctor if you have a history of liver disease, heart disease, kidney disease, migraine, epilepsy, or blood clotting disorders. Do not drive or operate heavy machinery if you experience dizziness or vision changes. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially fluid retention and liver toxicity. Dose should be individualized by a qualified clinician based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated in pregnancy. Women planning to become pregnant should stop this medicine and consult their doctor. Effective non-hormonal contraception should be used during treatment.
🏥 Post-Surgery Considerations
This medicine may increase the risk of blood clots after surgery. Inform your surgeon that you are taking this medicine. It may need to be stopped before surgery as advised by your doctor.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may increase the risk of bleeding during dental procedures. Your dentist may recommend stopping the medicine temporarily before the procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fluid retention. Avoid strenuous exercise if you experience these symptoms. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, vision changes, or mood swings, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how this medicine affects you. It may also cause menstrual irregularities, which can impact daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will determine the appropriate duration of treatment based on your condition and response. If you experience serious side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may cause liver toxicity, elevated liver enzymes, and rarely, hepatic adenomas. It can also cause virilization symptoms such as acne, hirsutism, and voice deepening, which may be irreversible. Regular monitoring of liver function, blood counts, and lipid profile is essential. The medicine should be used for the shortest duration necessary and under close medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedAnti-inflammatory diet may help reduce symptoms of endometriosis.
Evidence: LimitedMay help with pain management in some patients.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking your doses at the same intervals as prescribed. Check local customs regulations regarding prescription medicines before you travel. Always carry enough supply for the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of action varies. For hereditary angioedema, effects may be seen within days to weeks. For endometriosis, symptom relief may take several weeks to months.
A: This medicine can interact with several drugs, including warfarin, carbamazepine, and statins. Always inform your doctor about all medications you are taking.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, this medicine is contraindicated in pregnancy as it can harm the fetus. Use effective non-hormonal contraception during treatment.
🤔 Common Patient Concerns
🔄 Substitutes for benzol 100mg tablet
View AllAlternative brands with exact same active ingredient:
-
gynodan 100mg capsuleSanzyme Ltd ₹144.07 14.1% CHEAPER
-
danagil 100mg capsuleWerke Healthcare ₹154.69 7.8% CHEAPER
-
ladogal 100mg capsuleSanofi India Ltd ₹154.95 7.7% CHEAPER
-
danar 100mg capsuleArvincare Pharma ₹159.38 5% CHEAPER
-
gynadom 100mg tabletEast West Pharma ₹166.88 0.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Danazol is a hormone replacement therapy.
Fact: Danazol is not a hormone replacement therapy. It is a synthetic steroid used for specific conditions like endometriosis and hereditary angioedema. - Myth: Danazol can be taken during pregnancy.
Fact: Danazol is contraindicated in pregnancy as it can harm the fetus. Effective contraception is essential during treatment. - Myth: Danazol is safe for long-term use without monitoring.
Fact: Long-term use of danazol requires regular monitoring of liver function and other parameters due to potential side effects.
🔄 Alternative Options
Generic Alternatives
- Danazol 100 mg capsule
Brand Alternatives
- Danogen 100 capsule