bifozide 1% cream - Bifonazole (1% w/w) medicine

Bifozide 1% Cream - Uses, Price, Side Effects

4.5 (13 reviews)
๐Ÿญ Ikon Remedies Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is bifozide 1% cream used for?

Bifozide 1% Cream contains Bifonazole, an antifungal agent used to treat fungal skin infections like ringworm, athlete's foot, and jock itch. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes, leading to fungal cell death. Apply once daily for 2-4 weeks.

  • Generic Name: Bifonazole
  • Manufacturer: Ikon Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š bifozide 1% cream Uses & Benefits

Topical treatment of dermatophyte infections (tinea pedis, tinea cruris, tinea corporis), pityriasis versicolor, and cutaneous candidiasis.

Off-label uses: Seborrheic dermatitis, onychomycosis (as adjunct).

๐Ÿ“‹ Drug Information

Generic Name(s)Bifonazole
Brand NameBifrazo Cream
ManufacturerIkon Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationTopical.
StorageStore at room temperature (15-30ยฐC); keep tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after topical application; approximately 2-4% absorbed through intact skin.
DistributionDistributes mainly in the stratum corneum and epidermis; systemic distribution is negligible.
Protein BindingNot applicable due to minimal systemic absorption.
MetabolismHepatic via CYP450 enzymes, primarily CYP3A4, but metabolism is minimal due to low systemic absorption.
Half-LifeNot applicable for topical use; systemic half-life is not clinically relevant.
ExcretionPrimarily excreted in feces (biliary) and urine as metabolites; negligible systemic excretion.
BioavailabilityNot applicable for topical formulation.
Onset of ActionWithin 24-48 hours of application.
Peak Plasma TimeNot applicable; minimal systemic absorption.
Duration of ActionUp to 72 hours after single application due to prolonged skin retention.

How It Works

Inhibits ergosterol synthesis by blocking 14ฮฑ-demethylase, leading to accumulation of toxic sterols and fungal cell death.

Mechanism Steps

1Bifonazole binds to the heme iron of fungal CYP51 (14ฮฑ-demethylase).
2Inhibits the conversion of lanosterol to ergosterol.
3Depletes ergosterol in fungal cell membrane.

๐Ÿ’ก How to Take bifozide 1% cream

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of bifozide 1% cream

โœ… Common Side Effects

  • Local irritation
  • burning
  • stinging
  • erythema
  • pruritus

๐Ÿšจ Serious Side Effects

  • Allergic contact dermatitis
  • angioedema (rare)

โš ๏ธ Rare Side Effects

  • Bullous dermatitis
  • urticaria

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Corticosteroids (topical) Moderate May increase local side effects
Anticoagulants (oral) Minor No significant interaction expected

๐Ÿฝ๏ธ Food Interactions

None known.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to bifonazole or any component of the cream.

๐Ÿ“Š Monitoring Parameters

Clinical improvement; skin irritation; liver function tests if prolonged use.

๐Ÿคฑ Lactation Safety

Safe; minimal systemic absorption, unlikely to be excreted in breast milk.

๐Ÿ’Š Overdose Management

Overdose unlikely; if ingested, symptomatic treatment.

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for bifozide 1% cream

View All

Alternative brands with exact same active ingredient (Bifonazole (1% w/w)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory