acebran plus 100mg/600mg tablet - Acebrophylline (100mg) + Acetylcysteine (600mg) medicine

Acebran Plus 100mg/600mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Ikon Remedies Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is acebran plus 100mg/600mg tablet used for?

Acebran Plus 100mg/600mg Tablet is a combination of Acebrophylline (a bronchodilator) and Acetylcysteine (a mucolytic). It helps relieve symptoms of respiratory diseases like asthma and COPD by opening airways and thinning mucus, making breathing easier. It is manufactured by Ikon Remedies Pvt Ltd.

  • Generic Name: Acebrophylline + Acetylcysteine
  • Manufacturer: Ikon Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š acebran plus 100mg/600mg tablet Uses & Benefits

Chronic obstructive pulmonary disease (COPD), asthma, bronchitis, bronchiectasis

Off-label uses: Cystic fibrosis, Sinusitis

๐Ÿ“‹ Drug Information

Generic Name(s)Acebrophylline + Acetylcysteine
Brand NameAb-Flo-N Tablet
ManufacturerIkon Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic and Bronchodilator
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in body tissues
Protein BindingAcebrophylline: ~50%; Acetylcysteine: ~50%
MetabolismHepatic metabolism
Half-LifeAcebrophylline: 8-12 hours; Acetylcysteine: 5-6 hours
ExcretionRenal excretion
BioavailabilityAcebrophylline: ~70%; Acetylcysteine: ~10%
Onset of Action30-60 minutes
Peak Plasma Time1-3 hours
Duration of Action8-12 hours

How It Works

Acebrophylline: bronchodilation via phosphodiesterase inhibition and adenosine antagonism; Acetylcysteine: mucolysis by breaking disulfide bonds in mucus glycoproteins

Mechanism Steps

1Acebrophylline inhibits phosphodiesterase, increasing cAMP levels
2Acebrophylline blocks adenosine receptors, preventing bronchoconstriction
3Acetylcysteine reduces disulfide bonds in mucus, decreasing viscosity

๐Ÿ’ก How to Take acebran plus 100mg/600mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of acebran plus 100mg/600mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Heartburn
  • Headache
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Bronchospasm
  • Stevens-Johnson syndrome
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Hepatitis
  • Nephritis
  • Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Nitroglycerin Moderate Increased hypotension risk
Paracetamol Minor Possible reduced efficacy of acetylcysteine

๐Ÿšจ Major Interactions

  • Theophylline
  • Warfarin

โšก Moderate Interactions

  • Cimetidine
  • Ciprofloxacin

โ„น๏ธ Minor Interactions

  • Alcohol
  • Antacids

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

May increase risk of gastrointestinal irritation

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to any component, peptic ulcer, severe hepatic impairment

๐Ÿ“Š Monitoring Parameters

Pulmonary function tests, liver function tests, renal function tests

๐Ÿคฑ Lactation Safety

Caution advised; not recommended unless clearly needed

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; gastric lavage if indicated

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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