amenor 5mg tablet - Norethisterone (5mg) medicine

Cycloreg Tablet (Norethisterone 5 mg): Complete Guide

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🏭 Ikon Remedies Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Norethisterone is not recommended during pregnancy. It is classified as Pregnancy Category D by the FDA, meaning there is positive evidence of human fetal risk, but benefits may outweigh risks in certain serious conditions. However, current practice favors avoiding progestogens in pregnancy unless specifically indicated. Consult your doctor immediately if you become pregnant while taking this medicine. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for menstrual disorders; moderate for other uses.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden shortness of breath or chest pain
  • Swelling, pain, or redness in one leg
  • Severe headache with vision changes
  • Yellowing of skin or eyes
  • Severe abdominal pain
  • Heavy vaginal bleeding that soaks a pad every hour
  • Signs of allergic reaction such as rash, itching, or swelling of the face or throat

If experiencing severe symptoms, call emergency services immediately.

What is amenor 5mg tablet used for?

This medicine contains Norethisterone 5 mg, a synthetic progestogen used to treat heavy or irregular menstrual bleeding, endometriosis, and to delay menstruation. It works by mimicking progesterone to regulate the menstrual cycle and thin the uterine lining. It is taken orally as prescribed by a doctor.

  • Generic Name: Norethisterone
  • Manufacturer: Ikon Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 amenor 5mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा नोरेथिस्टेरोन 5 मिलीग्राम युक्त एक प्रोजेस्टोजन है, जिसका उपयोग भारी या अनियमित मासिक धर्म, एंडोमेट्रियोसिस, और मासिक धर्म को कुछ समय के लिए टालने के लिए किया जाता है। यह गर्भाशय की परत को पतला करके और मासिक चक्र को नियंत्रित करके काम करती है। यह दवा केवल डॉक्टर के परामर्श से ही लेनी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में अनियमित योनि रक्तस्राव, स्तन में कोमलता, मतली, सिरदर्द और मूड में बदलाव शामिल हैं। गंभीर दुष्प्रभावों में रक्त के थक्के बनना, गंभीर एलर्जी प्रतिक्रिया और लीवर की समस्या शामिल हो सकती है। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं, या स्तनपान करा रही हैं। यदि आपको रक्त के थक्के, लीवर की बीमारी, या अस्पष्ट योनि रक्तस्राव का इतिहास है तो यह दवा न लें। दवा को डॉक्टर के निर्देशानुसार ही लें। धूम्रपान से बचें क्योंकि इससे रक्त के थक्के बनने का खतरा बढ़ जाता है।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 amenor 5mg tablet Uses & Benefits

[{"condition":"Heavy menstrual bleeding (menorrhagia)","description":"This medicine helps reduce excessive menstrual blood loss by thinning the uterine lining and promoting normal shedding.","evidence":"Well-established"},{"condition":"Irregular menstrual bleeding","description":"It helps regulate the menstrual cycle and control abnormal bleeding patterns.","evidence":"Well-established"},{"condition":"Endometriosis","description":"This medicine can help reduce pain and lesions associated with endometriosis by suppressing endometrial tissue growth.","evidence":"Well-established"},{"condition":"Delay of menstruation","description":"It may be used to postpone menstruation for a short period for medical or personal reasons, under medical supervision.","evidence":"Well-established"},{"condition":"Breast pain (mastalgia)","description":"This medicine can help relieve cyclical breast pain associated with hormonal changes.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Hormone replacement therapy","description":"Sometimes used in combination with estrogen for women with an intact uterus to protect the uterine lining.","evidence":"Well-established"},{"condition":"Contraception","description":"Not a primary contraceptive, but may be used off-label in some regimens.","evidence":"Limited"}]

Primary treatment for: Heavy menstrual bleeding

Also treats: Irregular menstrual bleeding, Endometriosis, Breast pain

📋 Drug Information

Generic Name(s)Norethisterone
Brand NameAmenor 5mg Tablet
ManufacturerIkon Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassProgestins (First generation)
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent hormone levels.
2
Take with food or milk if it causes stomach upset.
3
Do not use this medicine as a contraceptive unless specifically prescribed for that purpose.
4
Inform your doctor if you experience any unusual vaginal bleeding, as the dose may need adjustment.
5
Avoid smoking while taking this medicine to reduce the risk of blood clots.
6
Keep all follow-up appointments to monitor your response and any potential side effects.
7
Do not stop taking this medicine abruptly without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Heavy menstrual bleeding
This medicine is commonly prescribed for this condition.
Likely Use
Irregular periods
This medicine helps regulate the menstrual cycle.
Likely Use
Pelvic pain due to endometriosis
This medicine can help reduce pain associated with endometriosis.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNorethisterone is rapidly absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability is approximately 64% due to first-pass metabolism. Peak plasma concentrations are reached within 1 to 2 hours after ingestion.
DistributionNorethisterone is widely distributed throughout the body. It is highly protein-bound, primarily to albumin and sex hormone-binding globulin. It crosses the placenta and is excreted in breast milk in small amounts.
Protein BindingApproximately 97% of norethisterone is bound to plasma proteins, mainly albumin and sex hormone-binding globulin.
MetabolismNorethisterone is extensively metabolized in the liver, primarily by reduction and conjugation with glucuronic acid and sulfate. Some metabolites may have weak progestational activity.
Half-LifeThe elimination half-life of norethisterone is approximately 5 to 12 hours.
ExcretionNorethisterone and its metabolites are excreted mainly in the urine, with a small amount excreted in feces.
BioavailabilityThe oral bioavailability of norethisterone is about 64%.
Onset of ActionThe onset of action varies depending on the indication. For control of menstrual bleeding, effects may be seen within 1 to 3 days. For endometrial transformation, it may take several days to weeks.
Peak Plasma TimePeak plasma concentrations are achieved within 1 to 2 hours after oral administration.
Duration of ActionThe duration of action depends on the dose and indication. For menstrual regulation, effects last for the duration of treatment. After stopping, withdrawal bleeding usually occurs within 2 to 7 days.

How It Works

This medicine works by binding to progesterone receptors in target tissues such as the endometrium, breast, and pituitary gland. By mimicking the natural hormone progesterone, it transforms the uterine lining from a proliferative state to a secretory state, which helps control abnormal bleeding. It also suppresses the release of gonadotropin-releasing hormone from the hypothalamus, leading to reduced production of follicle-stimulating hormone and luteinizing hormone from the pituitary. This results in decreased ovarian estrogen production and inhibition of ovulation. Additionally, it has some anti-estrogenic effects on the endometrium, which contributes to its therapeutic benefits in conditions like endometriosis and heavy menstrual bleeding.

Mechanism Steps

1
Binding to progesterone receptors: This medicine binds to progesterone receptors in the endometrium, breast, and pituitary gland, mimicking the action of natural progesterone.
2
Endometrial transformation: It transforms the uterine lining from a proliferative to a secretory state, which helps control abnormal bleeding and reduces heavy menstrual flow.
3
Suppression of ovulation: It inhibits the release of gonadotropin-releasing hormone, leading to reduced follicle-stimulating hormone and luteinizing hormone secretion, thereby preventing ovulation.
4
Anti-estrogenic effect: It counteracts estrogen's effects on the endometrium, causing it to thin over time, which is beneficial in conditions like endometriosis.

💡 How to Take amenor 5mg tablet

Strength: Norethisterone 5 mg immediate-release tablet

1Take this medicine by mouth with a glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with food or milk to reduce stomach upset.
4Take at the same time each day to maintain consistent levels.
5Follow your doctor's instructions regarding the duration of treatment.

Dosage Information

Adult DosageThe dose of this medicine varies depending on the condition being treated. For heavy menstrual bleeding, a common dose is 5 mg taken three times daily for 10 days, but this must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. For endometriosis, doses may range from 10 to 15 mg daily. For delaying menstruation, 5 mg three times daily may be used, starting 3 days before the expected period. Always follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageThere is limited data on the use of this medicine in elderly women. It should be used with caution, and the dose should be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentNo specific dose adjustment is provided in the literature. Use with caution in patients with renal impairment. Consult your doctor for individualized dosing.
Hepatic ImpairmentThis medicine is contraindicated in severe liver disease. In mild to moderate hepatic impairment, dose reduction may be necessary. Consult your doctor for individualized dosing.
Maximum Daily DoseThe maximum daily dose depends on the indication and should not exceed the prescribed amount. Typically, doses up to 15 mg per day are used, but higher doses may be prescribed in specific conditions. Always follow your doctor's advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Grapefruit
Avoid
May increase drug levels by inhibiting CYP3A4.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of amenor 5mg tablet

✅ Common Side Effects

Irregular vaginal bleeding or spotting (Common (10-30%))
This is often temporary. If bleeding is heavy or persistent, consult your doctor.
Breast tenderness (Common (5-10%))
Wear a supportive bra and reduce caffeine intake. Consult doctor if severe.
Nausea (Common (5-10%))
Take with food or at bedtime to reduce nausea.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if persistent.
Mood changes (Common (5-10%))
Discuss with your doctor if mood changes are bothersome.

🚨 Serious Side Effects

Blood clots (thrombosis) (Rare (<0.1%))
Seek immediate medical attention if you experience sudden shortness of breath, chest pain, or swelling in the leg.
Severe allergic reaction (Rare (<0.1%))
Seek emergency care if you develop rash, itching, swelling of the face or throat, or difficulty breathing.
Liver problems (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.

⚠️ Rare Side Effects

Visual disturbances
Consult an eye specialist if you notice changes in vision.
Fluid retention
Reduce salt intake and consult your doctor if swelling occurs.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Rifampicin Major
Carbamazepine Major
Phenytoin Moderate
St John's Wort Moderate
Grapefruit juice Moderate

🚨 Major Interactions

  • Warfarin
  • Rifampicin
  • Carbamazepine

⚡ Moderate Interactions

  • Phenytoin
  • St John's Wort

🍷 Alcohol Interaction

Alcohol may increase the risk of liver problems and can worsen side effects such as dizziness or mood changes. It is advisable to limit or avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy or suspected pregnancy","Active or history of thromboembolic disorders (e.g., deep vein thrombosis, pulmonary embolism)","Severe liver disease","Undiagnosed vaginal bleeding","Known or suspected breast cancer","Hypersensitivity to norethisterone or any component of the formulation"]

⚠️ Warnings & Precautions

["Use with caution in patients with a history of depression.","May cause fluid retention; caution in patients with hypertension, epilepsy, or migraine.","May affect glucose tolerance; monitor blood sugar in diabetic patients.","Avoid smoking while taking this medicine due to increased cardiovascular risk.","Do not use for emergency contraception.","May cause irregular bleeding; report persistent or heavy bleeding to your doctor.","Long-term use may increase the risk of breast cancer; regular breast examinations are advised."]

🤱 Lactation Safety

Norethisterone is excreted in breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks. Some experts recommend avoiding it in the first 6 weeks postpartum due to potential effects on milk production.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, and withdrawal bleeding. There is no specific antidote. Treatment should be symptomatic and supportive. If a large overdose is suspected, seek immediate medical attention.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not take this medicine if you have a history of blood clots, liver disease, or unexplained vaginal bleeding. Take this medicine exactly as prescribed by your doctor. Do not share this medicine with others, even if they have similar symptoms. Keep all appointments with your doctor for regular monitoring. Avoid smoking while taking this medicine, as it increases the risk of blood clots. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Store this medicine at room temperature, away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly women may be more sensitive to the side effects of this medicine, especially cardiovascular events. Use with caution and monitor blood pressure and liver function regularly. The dose should be individualized by a qualified clinician.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended if you are trying to conceive. It may affect the menstrual cycle and ovulation. If you are planning pregnancy, consult your doctor to discuss alternative treatments. If you become pregnant while taking this medicine, stop it immediately and consult your doctor.

🏥 Post-Surgery Considerations

This medicine may increase the risk of blood clots after surgery. Inform your surgeon that you are taking this medicine. Your doctor may advise stopping it before surgery or taking precautions to prevent clots.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, especially if you have a history of bleeding disorders or are on anticoagulants. No specific precautions are usually needed for routine dental work, but your dentist may take extra care if you have a bleeding tendency.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce the risk of thromboembolic events.
🥗
Engage in regular physical activity, but avoid strenuous exercise if you feel dizzy.
😴
Eat a balanced diet rich in fruits, vegetables, and whole grains.
💧
Avoid smoking and limit alcohol consumption.
🧘
Practice stress-reducing techniques such as yoga or meditation.
🌞
Get adequate sleep to support hormonal balance.

🏋️ Exercise Considerations

This medicine may cause dizziness or fatigue in some individuals. Avoid strenuous exercise or activities requiring alertness until you know how the medicine affects you. If you experience leg pain or swelling, avoid exercise and consult your doctor.

🥗 Diet Recommendations

Include foods rich in iron to prevent anemia from heavy bleeding.
Reduce salt intake to minimize fluid retention.
Avoid grapefruit and grapefruit juice.
Stay well hydrated.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, headache, or mood changes, which can affect your ability to drive or operate machinery. Avoid driving if you feel dizzy or drowsy. It is advisable to inform your employer if your work involves operating heavy machinery. Most women can continue their normal activities, but listen to your body and rest when needed.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as blood clots, severe allergic reactions, or liver problems, seek immediate medical attention and stop the medicine as advised by your doctor. For short-term use, follow the prescribed duration. For long-term use, your doctor will periodically review whether to continue.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of breast cancer, liver tumors, and thromboembolic events. Regular monitoring of liver function, blood pressure, and breast examinations are advised. It should be used at the lowest effective dose for the shortest duration necessary. Consult your doctor for regular check-ups if you are on long-term therapy.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Non-hormonal treatments

Tranexamic acid or NSAIDs can be used for heavy menstrual bleeding.

Evidence: Well-established
Lifestyle modifications

Weight loss, exercise, and dietary changes can help manage menstrual disorders.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, continue taking the medicine at the same interval as prescribed, but consult your doctor for specific advice. Check local customs regulations regarding prescription medicines before travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with heavy menstrual bleeding
She was prescribed this medicine for 10 days to control excessive bleeding. She noticed a significant reduction in bleeding within 2 days. She experienced mild nausea initially, which subsided when she took the tablet with food. She completed the course as advised and her cycles became more regular.
💡 Lesson: Taking this medicine with food can reduce nausea, and completing the prescribed course is important for optimal results.
👤 A 28-year-old woman needing to delay her period for a wedding
She consulted her doctor to postpone her period for a week. She was prescribed this medicine to start 3 days before her expected date. She took it as directed and successfully delayed her period without significant side effects. She experienced mild breast tenderness, which resolved after stopping the medicine.
💡 Lesson: This medicine can effectively delay menstruation when taken under medical supervision, but it should not be used regularly for this purpose.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: For control of menstrual bleeding, effects may be seen within 1 to 3 days. For other uses, it may take longer. Follow your doctor's instructions.

Q: Can I take this medicine if I am pregnant?

A: No, this medicine is not recommended during pregnancy. Consult your doctor immediately if you become pregnant while taking it.

Q: Does this medicine cause weight gain?

A: Weight gain is not a common side effect, but some women may experience fluid retention. Consult your doctor if you notice significant weight changes.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my fertility?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for amenor 5mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a contraceptive pill.
    Fact: This medicine is not a contraceptive unless specifically prescribed for that purpose. It is primarily used for menstrual disorders.
  • Myth: This medicine can be used for emergency contraception.
    Fact: This medicine is not an emergency contraceptive. It should not be used for this purpose.
  • Myth: This medicine causes abortion.
    Fact: This medicine is not an abortifacient. It should not be used to terminate a pregnancy.

🔄 Alternative Options

Generic Alternatives

  • Norethisterone 5 mg tablet

Brand Alternatives

  • Primolut N
  • Regestrone

📊 Comparison with Similar Medicines

[{"medicine":"Norethisterone","class":"Progestogen","primary_use":"Heavy menstrual bleeding","half_life":"5-12 hours"},{"medicine":"Medroxyprogesterone acetate","class":"Progestogen","primary_use":"Menstrual disorders, contraception","half_life":"12-24 hours"}]

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