azafly 50mg tablet - Uses, Price, Side Effects & Substitutes
What is azafly 50mg tablet used for?
Azoran Tablet (Azathioprine) is used to treat ANTI NEOPLASTICS. It contains Azathioprine (50mg), which Azathioprine is a purine analog that inhibits DNA and RNA synthesis, suppressing. Always consult your doctor before use. Take as prescribed.
- Generic Name: Azathioprine
- Manufacturer: Brinton Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ azafly 50mg tablet Uses & Benefits
Prevention of organ transplant rejection, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease (Crohn's disease, ulcerative colitis), autoimmune hepatitis.
Off-label uses: Behรงet's disease, myasthenia gravis, pemphigus vulgaris, atopic dermatitis, multiple sclerosis.
๐ Drug Information
| Generic Name(s) | Azathioprine |
| Brand Name | Azoran Tablet |
| Manufacturer | Brinton Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Immunosuppressant- Purine analogs |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Azathioprine is a purine analog that inhibits DNA and RNA synthesis, suppressing immune cell proliferation.
Mechanism Steps
๐ก How to Take azafly 50mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of azafly 50mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Leukopenia
- Anemia
- Thrombocytopenia
- Increased liver enzymes
๐จ Serious Side Effects
- Severe bone marrow suppression
- Hepatotoxicity
- Pancreatitis
- Serious infections
- Lymphoma
- Skin cancer
โ ๏ธ Rare Side Effects
- Pulmonary fibrosis
- Venocclusive disease of liver
- Alopecia
- Rash
- Arthralgia
- Hypersensitivity reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Allopurinol | Major | Increased azathioprine toxicity; reduce dose. |
| Warfarin | Major | Decreased anticoagulant effect; monitor INR. |
| Ribavirin | Major | Increased myelosuppression risk. |
| Febuxostat | Major | Increased azathioprine levels; avoid. |
| Co-trimoxazole | Major | Increased myelosuppression risk. |
| ACE inhibitors | Moderate | Increased risk of anemia and leukopenia. |
| Methotrexate | Moderate | Increased hepatotoxicity risk. |
| Cyclosporine | Moderate | Increased immunosuppression; monitor. |
| Infliximab | Moderate | Increased infection risk. |
| Mycophenolate | Moderate | Increased immunosuppression; monitor. |
| Antacids | Minor | Decreased absorption; separate by 2 hours. |
| Oral contraceptives | Minor | Possible reduced efficacy of contraceptives. |
| Cimetidine | Minor | Increased azathioprine levels. |
| Furosemide | Minor | Possible increased toxicity. |
| Indomethacin | Minor | Increased myelosuppression risk. |
๐จ Major Interactions
- Allopurinol
- Warfarin
- Ribavirin
- Febuxostat
- Co-trimoxazole
โก Moderate Interactions
- ACE inhibitors
- Methotrexate
- Cyclosporine
- Infliximab
- Mycophenolate
โน๏ธ Minor Interactions
- Antacids
- Oral contraceptives
- Cimetidine
- Furosemide
- Indomethacin
๐ฝ๏ธ Food Interactions
Grapefruit may increase levels; avoid.
๐ท Alcohol Interaction
Alcohol may increase hepatotoxicity risk; avoid or limit.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to azathioprine, severe infections, pregnancy (unless essential), lactation, severe bone marrow suppression.
๐ Monitoring Parameters
Complete blood count (CBC), liver function tests (LFTs), renal function, TPMT genotype before therapy.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk; may cause immunosuppression in infant.
๐ Overdose Management
Induce vomiting or gastric lavage; monitor for myelosuppression; supportive care; consider hemodialysis.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for azafly 50mg tablet
View AllAlternative brands with exact same active ingredient (Azathioprine (50mg)):
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davaindia azathioprine 50mg tabletDavaindia Generic Pharmacy โน30.00 71.8% CHEAPER
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imuzat 50mg tabletElder Pharmaceuticals Ltd โน55.12 48.1% CHEAPER
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azithioprine 50mg tabletAlkem Laboratories Ltd โน58.50 44.9% CHEAPER
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a pin 50mg tabletParry Pharma Pvt Ltd โน60.00 43.5% CHEAPER
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transimune 50mg tabletTroikaa Pharmaceuticals Ltd โน67.26 36.7% CHEAPER
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azap 50 tabletChandra Bhagat Pharma Pvt Ltd โน75.00 29.4% CHEAPER
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neoprine 50mg tabletEumedica Pharmaceuticals โน77.34 27.2% CHEAPER
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azimune 50mg tabletSun Pharmaceutical Industries Ltd โน79.80 24.9% CHEAPER
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zesoris-az 50mg tabletTas Med India Pvt Ltd โน80.00 24.7% CHEAPER
-
azoprine 50mg tabletVhb Life Sciences Inc โน82.00 22.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.