azithioprine 50mg tablet - Uses, Price, Side Effects & Substitutes
What is azithioprine 50mg tablet used for?
Azoran Tablet (Azathioprine) is used to treat Prevention of organ transplant rejection. It contains Azathioprine (50mg), which Azathioprine is a purine analog that inhibits DNA and RNA synthesis, suppressing. Always consult your doctor before use. Take as prescribed.
- Generic Name: Azathioprine
- Manufacturer: Alkem Laboratories Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 azithioprine 50mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
azithioprine 50mg tablet का उपयोग मुख्य रूप से anti neoplastics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Azathioprine (50mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Azathioprine |
|---|---|
| Brand Name | Azoran Tablet |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Immunosuppressant- Purine analogs |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take azithioprine 50mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from light and moisture.
⚙️ How azithioprine 50mg tablet Works
Azathioprine is a purine analog that inhibits DNA and RNA synthesis, suppressing immune cell proliferation.
💊 azithioprine 50mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Prevention of organ transplant rejection, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease (Crohn's disease, ulcerative colitis), autoimmune hepatitis.
Off-label uses: Behçet's disease, myasthenia gravis, pemphigus vulgaris, atopic dermatitis, multiple sclerosis.
⚠️ What are the side effects of azithioprine 50mg tablet?
✅ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Leukopenia
- Anemia
- Thrombocytopenia
- Increased liver enzymes
🚨 Serious Side Effects
- Severe bone marrow suppression
- Hepatotoxicity
- Pancreatitis
- Serious infections
- Lymphoma
- Skin cancer
⚠️ Rare Side Effects
- Pulmonary fibrosis
- Venocclusive disease of liver
- Alopecia
- Rash
- Arthralgia
- Hypersensitivity reactions
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Allopurinol | Major | Increased azathioprine toxicity; reduce dose. |
| Warfarin | Major | Decreased anticoagulant effect; monitor INR. |
| Ribavirin | Major | Increased myelosuppression risk. |
| Febuxostat | Major | Increased azathioprine levels; avoid. |
| Co-trimoxazole | Major | Increased myelosuppression risk. |
| ACE inhibitors | Moderate | Increased risk of anemia and leukopenia. |
| Methotrexate | Moderate | Increased hepatotoxicity risk. |
| Cyclosporine | Moderate | Increased immunosuppression; monitor. |
| Infliximab | Moderate | Increased infection risk. |
| Mycophenolate | Moderate | Increased immunosuppression; monitor. |
| Antacids | Minor | Decreased absorption; separate by 2 hours. |
| Oral contraceptives | Minor | Possible reduced efficacy of contraceptives. |
| Cimetidine | Minor | Increased azathioprine levels. |
| Furosemide | Minor | Possible increased toxicity. |
| Indomethacin | Minor | Increased myelosuppression risk. |
🚨 Major Interactions
- Allopurinol
- Warfarin
- Ribavirin
- Febuxostat
- Co-trimoxazole
⚡ Moderate Interactions
- ACE inhibitors
- Methotrexate
- Cyclosporine
- Infliximab
- Mycophenolate
ℹ️ Minor Interactions
- Antacids
- Oral contraceptives
- Cimetidine
- Furosemide
- Indomethacin
🍽️ Food Interactions
Grapefruit may increase levels; avoid.
🍷 Alcohol Interaction
Alcohol may increase hepatotoxicity risk; avoid or limit.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to azathioprine, severe infections, pregnancy (unless essential), lactation, severe bone marrow suppression.
📊 Monitoring Parameters
Complete blood count (CBC), liver function tests (LFTs), renal function, TPMT genotype before therapy.
🤱 Lactation Safety
Not recommended; excreted in breast milk; may cause immunosuppression in infant.
💊 Overdose Management
Induce vomiting or gastric lavage; monitor for myelosuppression; supportive care; consider hemodialysis.
⏰ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
🛑 Myths vs. Facts about azithioprine 50mg tablet
- Myth: Generic substitutes of azithioprine 50mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Azathioprine (50mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of azithioprine 50mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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