Avspas Oral Drop: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe abdominal pain with vomiting or no bowel movement
- Blood in stool or vomit
- Inability to pass urine or severe lower abdominal pain
- Fast, irregular heartbeat or chest pain
- Extreme drowsiness, confusion, or seizures
- Yellowing of skin or eyes, or dark urine
- Persistent high fever with rash
If experiencing severe symptoms, call emergency services immediately.
What is avspas oral drop used for?
This medicine is an oral drop combination of dicyclomine and simethicone used to relieve abdominal cramps, colic, and gas-related bloating. Dicyclomine relaxes gut muscles, while simethicone helps trapped gas pass more easily. It should be used only under a doctor's supervision.
- Generic Name: Dicyclomine (10mg/ml) + Simethicone (40mg/ml)
- Manufacturer: Afive Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 avspas oral drop के बारे में (Hindi Summary)
उपयोग: यह दवा डाइसाइक्लोमिन और सिमेथिकोन का संयोजन है, जो पेट में ऐंठन, गैस, सूजन और शिशुओं के पेट दर्द (कोलिक) में राहत देने के लिए इस्तेमाल की जाती है। डाइसाइक्लोमिन आंतों की मांसपेशियों को आराम देता है, जिससे दर्द कम होता है, और सिमेथिकोन गैस के बुलबुले को तोड़कर बाहर निकालने में मदद करता है। यह दवा केवल डॉक्टर की सलाह पर ही दी जानी चाहिए, खासकर शिशुओं और बच्चों को।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, नींद आना, चक्कर आना, धुंधला दिखना, जी मिचलाना और कब्ज शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। अगर पेशाब करने में दिक्कत, तेज़ धड़कन, गंभीर कब्ज, या चेहरे-गले में सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग केवल डॉक्टर के पर्चे पर ही करें। ड्रॉपर से सही मात्रा नापें, चम्मच से न दें। दवा लेने के बाद नींद या चक्कर आए तो वाहन न चलाएँ। शराब और अन्य नींद लाने वाली दवाओं से बचें। बच्चों की पहुँच से दूर रखें। अगर लक्षण ठीक न हों या बिगड़ें, तो डॉक्टर से मिलें।
💊 avspas oral drop Uses & Benefits
[{"condition":"Infantile colic and abdominal cramps","description":"This medicine helps relax intestinal smooth muscle and reduces trapped gas, easing crying and discomfort in infants with colic when prescribed by a pediatrician.","evidence":"Commonly used in clinical practice"},{"condition":"Functional gastrointestinal disorders with bloating","description":"It is used to relieve bloating, fullness, and cramping associated with functional bowel disorders.","evidence":"Commonly used in clinical practice"},{"condition":"Biliary and urinary tract spasm","description":"Dicyclomine component may help reduce smooth muscle spasm in biliary or urinary colic, while simethicone addresses gas.","evidence":"Limited to selected clinical settings"},{"condition":"Post-operative abdominal distension","description":"Sometimes used to relieve gas-related distension after surgery under medical supervision.","evidence":"Limited"}]
Off-label uses: [{"condition":"Irritable bowel syndrome with predominant diarrhea","description":"Dicyclomine may be used off-label for cramping in IBS, but this oral drop combination is not a standard first-line form for adults.","evidence":"Limited"},{"condition":"Motion sickness with gas","description":"Not a standard use; dicyclomine is not primarily an antiemetic and should not replace proven motion sickness treatments.","evidence":"Not established from the available information."}]
Primary treatment for: Infantile colic and abdominal cramps with gas
Also treats: Functional gastrointestinal disorders, Irritable bowel syndrome (cramping), Biliary colic, Post-operative abdominal distension
📋 Drug Information
| Generic Name(s) | Dicyclomine (10mg/ml) + Simethicone (40mg/ml) |
| Brand Name | avspas oral drop |
| Manufacturer | Afive Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the bottle tightly closed. Do not freeze. Keep out of reach of children. |
| Shelf Life | Refer to the expiry date printed on the pack. Do not use after the expiry date. Once opened, use within the period recommended by the manufacturer, usually within 30 days unless otherwise stated. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Dicyclomine is a synthetic antispasmodic with anticholinergic properties that blocks muscarinic acetylcholine receptors on gastrointestinal smooth muscle, reducing muscle contraction and spasm. Simethicone is a silicone-based antifoaming agent that lowers the surface tension of gas bubbles in the gut, causing small bubbles to coalesce into larger ones that are easier to pass. The result is reduced cramping and less trapped gas, which together ease abdominal pain and bloating.
Mechanism Steps
💡 How to Take avspas oral drop
Strength: Oral drops containing dicyclomine 10 mg/ml and simethicone 40 mg/ml. The product is supplied in a dropper bottle for oral administration.
Dosage Information
| Adult Dosage | The adult dose of this medicine is not fixed and must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, and renal and hepatic function. Typically, dicyclomine is prescribed in divided doses, but the exact dose and frequency for this oral drop formulation should be determined only by the treating doctor. Do not self-medicate or adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Dicyclomine is generally not recommended for infants below 6 months of age due to serious respiratory risks. For older children, the dose must be calculated by a pediatrician based on weight and clinical condition. |
| Elderly Dosage | Elderly patients are more sensitive to the anticholinergic effects of dicyclomine, including confusion, constipation, dry mouth, and urinary retention. The dose should be started low and adjusted cautiously by a clinician. Regular monitoring for mental status changes and urinary symptoms is advised. |
| Renal Impairment | In patients with severe renal impairment, dicyclomine may accumulate and increase the risk of side effects. Dose reduction or avoidance may be necessary. Consult a nephrologist or prescribing doctor for individualized dosing. |
| Hepatic Impairment | Dicyclomine is metabolized in the liver. In patients with severe hepatic impairment, clearance may be reduced. Use with caution and consider dose reduction under medical supervision. |
| Maximum Daily Dose | The maximum daily dose must be determined by the prescribing clinician based on the patient's age, weight, and clinical condition. Do not exceed the prescribed dose. For educational reference, adult dicyclomine doses generally should not exceed 160 mg per day, but this oral drop formulation should only be used as directed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of avspas oral drop
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Atropine | Major | |
| Tricyclic antidepressants | Major | |
| Potassium chloride | Major | |
| Amantadine | Major | |
| Opioids | Moderate | |
| Levodopa | Moderate | |
| Antacids | Moderate | |
| Levothyroxine | Minor | |
| Warfarin | Minor | |
| Metoclopramide | Moderate |
🚨 Major Interactions
- Other anticholinergic drugs (e.g., atropine, antihistamines, tricyclic antidepressants)
- Potassium chloride solid oral dosage forms
- Amantadine
⚡ Moderate Interactions
- Antacids containing aluminum or magnesium
- Opioid analgesics
- Levodopa
🍷 Alcohol Interaction
Alcohol may increase drowsiness, dizziness, and impaired coordination caused by dicyclomine. Avoid alcohol while taking this medicine, especially if you need to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to dicyclomine, simethicone, or any component of the formulation","Glaucoma (narrow-angle)","Myasthenia gravis","Paralytic ileus or obstructive uropathy","Severe ulcerative colitis or toxic megacolon","Infants less than 6 months of age unless specifically prescribed by a pediatrician","Breastfeeding without medical advice"]
⚠️ Warnings & Precautions
["May cause drowsiness and blurred vision; avoid driving or operating machinery until you know how it affects you.","Use with caution in elderly patients due to increased risk of confusion, constipation, and urinary retention.","Do not use in patients with untreated narrow-angle glaucoma.","May worsen gastroesophageal reflux disease (GERD).","Use with caution in patients with autonomic neuropathy, hyperthyroidism, or coronary heart disease.","Do not exceed the prescribed dose; serious anticholinergic toxicity can occur.","Keep out of reach of children; accidental ingestion can be dangerous."]
🤱 Lactation Safety
It is not known whether dicyclomine passes into breast milk in significant amounts. Simethicone is not absorbed and is unlikely to affect a breastfed infant. Because dicyclomine may reduce milk production and cause infant drowsiness, breastfeeding mothers should consult a doctor before using this medicine.
💊 Overdose Management
Overdose of this medicine may cause severe anticholinergic symptoms such as dry mouth, flushing, dilated pupils, blurred vision, fast heartbeat, fever, confusion, hallucinations, urinary retention, and seizures. If overdose is suspected, seek emergency medical care immediately. Treatment is supportive and may include activated charcoal if given early, intravenous fluids, and medications to control seizures or arrhythmias. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Use this medicine only when prescribed by a qualified clinician. Measure the dose accurately with the dropper supplied with the bottle, and never use a household spoon. Do not increase the dose or frequency on your own. Avoid driving or operating heavy machinery if you feel drowsy or have blurred vision. Do not combine with alcohol or other sedating medicines without medical advice. Inform your doctor about all other medicines, especially anticholinergics, antihistamines, antidepressants, and drugs for urinary or eye problems. Keep this medicine out of reach of children. Store it as directed on the label, and check the expiry date before each use. If symptoms do not improve within the expected time or become worse, contact your doctor instead of continuing self-adjustment.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to anticholinergic side effects such as confusion, constipation, dry mouth, and urinary retention. Use with caution, start at a low dose, and monitor mental status and urinary function regularly.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. Dicyclomine should be used only if clearly needed. Simethicone is generally considered low risk. Discuss all medicines with your obstetrician.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to relieve gas and abdominal distension, but only under medical supervision. It may interact with other post-operative medications. Inform your surgeon and anesthesiologist about all medicines you are taking.
🦷 Dental Procedures
This medicine may cause dry mouth, which can increase the risk of dental problems. Maintain good oral hygiene and stay hydrated. Inform your dentist if you are taking this medicine, especially before any procedure requiring sedation.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring balance until you know how it affects you. Light walking is generally safe and may help with gas passage.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and blurred vision, which may affect your ability to drive, operate machinery, or perform tasks requiring alertness. Avoid these activities until you know how the medicine affects you. Discuss work adjustments with your doctor if needed.
🛑 When to Stop This Medicine
Stop this medicine and consult your doctor if symptoms improve and the prescribed course is complete, or if you experience serious side effects such as difficulty breathing, severe abdominal pain, urinary retention, or allergic reactions. Do not stop abruptly if you are on a long-term prescription without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine should be avoided unless prescribed and monitored by a doctor. Prolonged dicyclomine use may lead to persistent dry mouth, constipation, urinary retention, and, in elderly patients, cognitive changes. Regular review of symptoms and dose is recommended. Simethicone is generally safe for long-term use as it is not absorbed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For gas and bloating without cramps, simethicone alone may be sufficient.
Evidence: Commonly usedMay help with colic and digestive health in some infants.
Evidence: LimitedEliminating gas-producing foods can reduce symptoms.
Evidence: Well-established for gasNon-drug methods to help infants pass gas.
Evidence: Commonly used💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if a child is unwell with fever or severe symptoms, vaccination may be postponed as advised by the pediatrician.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container with dropper
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of the prescription and a doctor's note if traveling internationally, especially with an infant. Store at room temperature and protect from direct sunlight. If crossing time zones, continue the dosing schedule as advised by your doctor, but do not double doses. Check customs regulations for carrying prescription liquids.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Dicyclomine usually starts working within 30 to 60 minutes after oral administration. Simethicone may act within minutes to hours. If symptoms do not improve, consult your doctor.
A: This medicine can interact with other anticholinergic drugs, opioids, and some antacids. Always inform your doctor about all medicines you or your child are taking.
A: It should only be used in infants under a pediatrician's supervision. Dicyclomine is generally not recommended for infants below 6 months due to serious respiratory risks.
A: Take the missed dose as soon as you remember if it is not almost time for the next dose. Otherwise, skip it and continue the regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for avspas oral drop
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any stomach pain.
Fact: This medicine is specifically for cramps and gas. It does not treat infections, ulcers, or acid reflux and should not be used for all types of stomach pain. - Myth: More drops mean faster relief.
Fact: Taking more than the prescribed dose can cause serious anticholinergic side effects. Always follow the doctor's dose. - Myth: It is safe to give to newborns for colic.
Fact: Dicyclomine is not recommended for infants below 6 months due to serious respiratory risks. Only a pediatrician can decide if it is appropriate.
🔄 Alternative Options
Generic Alternatives
- Dicyclomine and simethicone oral drops (generic versions may be available)
Brand Alternatives
- Colimex Oral Drops
- Colicaid Drops
- Dicyclomine and Simethicone Oral Drops (various manufacturers)