avom 10mg tablet dt

4.2 (15 reviews)

Domperidone (10mg)

🏭 Win-Medicare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is avom 10mg tablet dt used for?

Actidom 5mg Oral Suspension (Domperidone) is used to treat GASTRO INTESTINAL. It contains Domperidone (10mg), which Domperidone is a dopamine D2 receptor antagonist that acts primarily in the chem. Always consult your doctor before use. Take as prescribed.

Generic Name: Domperidone
Manufacturer: Win-Medicare Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 avom 10mg tablet dt Uses & Benefits

Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, nausea and vomiting (including chemotherapy-induced), and to promote gastric emptying.

Off-label uses: Migraine-associated nausea, postoperative nausea and vomiting, diabetic gastroparesis, functional dyspepsia.

📋 Drug Information

Generic Name(s)	Domperidone
Brand Name	Actidom 5mg Oral Suspension
Manufacturer	Win-Medicare Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GASTRO INTESTINAL
Action Class	Dopamine (D2) receptor antagonist-Prokinetic agent
Route of Administration	Oral
Storage	Store at room temperature (20-25°C). Protect from light and moisture. Keep bottle tightly closed.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentrations occur within 30-60 minutes. Bioavailability is approximately 13-17% due to extensive first-pass metabolism.

DistributionWidely distributed in body tissues; crosses the blood-brain barrier to a limited extent. Volume of distribution is about 5.7 L/kg.

Protein Binding91-93% bound to plasma proteins, primarily albumin.

MetabolismExtensively metabolized in the liver via CYP3A4 and CYP2D6 isoenzymes; major metabolites are hydroxylated and N-dealkylated products.

Half-Life7-9 hours in healthy individuals; prolonged in renal impairment.

ExcretionApproximately 31% excreted in urine (mostly as metabolites) and 66% in feces.

Bioavailability13-17% (oral)

Onset of Action30-60 minutes

Peak Plasma Time30-60 minutes

Duration of Action4-6 hours

How It Works

Domperidone is a dopamine D2 receptor antagonist that acts primarily in the chemoreceptor trigger zone (CTZ) and gastrointestinal tract. It blocks dopamine receptors, increasing lower esophageal sphincter pressure, enhancing gastric motility and peristalsis, and accelerating gastric emptying.

Mechanism Steps

1Domperidone binds to and blocks dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) and gastrointestinal tract.

2Blockade of D2 receptors in the CTZ reduces the sensation of nausea and vomiting.

3In the GI tract, D2 receptor blockade increases lower esophageal sphincter pressure.

💡 How to Take avom 10mg tablet dt

Follow your doctor's prescription exactly.

⚠️ Side Effects of avom 10mg tablet dt

✅ Common Side Effects

Dry mouth
Headache
Diarrhea
Abdominal cramps
Galactorrhea
Gynecomastia
Amenorrhea

🚨 Serious Side Effects

QT prolongation
Torsades de pointes
Cardiac arrest
Extrapyramidal symptoms (dystonia, akathisia)
Neuroleptic malignant syndrome (rare)

⚠️ Rare Side Effects

Allergic reactions (rash, urticaria)
Seizures
Hepatotoxicity
Leukopenia
Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Ketoconazole	Major	Increased risk of QT prolongation and cardiac arrhythmias
Erythromycin	Major	Increased risk of QT prolongation
Clarithromycin	Major	Increased risk of QT prolongation
Amiodarone	Major	Increased risk of QT prolongation
Quinidine	Major	Increased risk of QT prolongation
Fluconazole	Major	Increased risk of QT prolongation
Ritonavir	Major	Increased risk of QT prolongation
Saquinavir	Major	Increased risk of QT prolongation
Telaprevir	Major	Increased risk of QT prolongation
Voriconazole	Major	Increased risk of QT prolongation
Cimetidine	Moderate	Reduced absorption of domperidone
Ranitidine	Moderate	Reduced absorption of domperidone
Omeprazole	Moderate	Reduced absorption of domperidone
Phenothiazines	Moderate	Increased risk of extrapyramidal symptoms
Tricyclic antidepressants	Moderate	Increased risk of QT prolongation
SSRIs	Moderate	Increased risk of QT prolongation
MAOIs	Moderate	Increased risk of hypertensive crisis
Lithium	Moderate	Increased risk of extrapyramidal symptoms
Opioid analgesics	Moderate	Antagonism of gastrointestinal prokinetic effect
Anticholinergics	Moderate	Antagonism of gastrointestinal prokinetic effect
Aluminum-containing antacids	Minor	Reduced absorption of domperidone
Sucralfate	Minor	Reduced absorption of domperidone
Digoxin	Minor	Reduced absorption of digoxin
Paracetamol	Minor	No significant interaction
Diazepam	Minor	No significant interaction

🚨 Major Interactions

Ketoconazole
Erythromycin
Clarithromycin
Amiodarone
Quinidine
Fluconazole
Ritonavir
Saquinavir
Telaprevir
Voriconazole

⚡ Moderate Interactions

Cimetidine
Ranitidine
Omeprazole
Phenothiazines
Tricyclic antidepressants
SSRIs
MAOIs
Lithium
Opioid analgesics
Anticholinergics

ℹ️ Minor Interactions

Aluminum-containing antacids
Sucralfate
Digoxin
Paracetamol
Diazepam

🍽️ Food Interactions

Food may reduce absorption; take 15-30 minutes before meals. Grapefruit juice may increase plasma levels.

🍷 Alcohol Interaction

Alcohol may enhance sedative effects and increase risk of extrapyramidal symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to domperidone; prolactinoma; gastrointestinal hemorrhage, obstruction, or perforation; moderate to severe hepatic impairment; known QT prolongation or concurrent use of QT-prolonging drugs.

📊 Monitoring Parameters

ECG for QT interval in patients at risk; renal function; signs of extrapyramidal symptoms; gastrointestinal symptoms.

🤱 Lactation Safety

Excreted in breast milk; use with caution. May cause adverse effects in nursing infants.

💊 Overdose Management

Symptoms: drowsiness, disorientation, extrapyramidal reactions. Treatment: gastric lavage, activated charcoal, supportive care. Anticholinergic agents may be used for extrapyramidal symptoms.

⏰ Missed Dose

Take the missed dose as soon as remembered. If it is almost time for the next dose, skip the missed dose. Do not double the dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for avom 10mg tablet dt

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Alternative brands with exact same active ingredient (Domperidone (10mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

avom 10mg tablet dt

What is avom 10mg tablet dt used for?

💊 avom 10mg tablet dt Uses & Benefits

📋 Drug Information

🔬 Pharmacology (PK/PD)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take avom 10mg tablet dt

⚠️ Side Effects of avom 10mg tablet dt

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

ℹ️ Minor Interactions

🍽️ Food Interactions

🍷 Alcohol Interaction

🛡️ Safety & Warnings

🚫 Contraindications

📊 Monitoring Parameters

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

🔄 Substitutes for avom 10mg tablet dt

⭐ User Reviews

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