Avistep 2mg/100mg Capsule: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- High fever with chills
- Severe abdominal pain or bloating
- Signs of dehydration (dry mouth, reduced urine, dizziness)
- Swelling of face, lips, or throat
- Difficulty breathing or chest pain
- Unusual tiredness, bruising, or bleeding
- Numbness or tingling in hands or feet
If experiencing severe symptoms, call emergency services immediately.
What is avistep 2mg/100mg capsule used for?
This medicine is a combination of loperamide and furazolidone used for short-term treatment of acute infectious diarrhoea. It works by slowing gut movement and fighting susceptible bacteria and parasites. It should be taken only as prescribed and avoided in bloody diarrhoea, children under 12, pregnancy, and with alcohol.
- Generic Name: Loperamide (2mg) + Furazolidone (100mg)
- Manufacturer: Bhavishya Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 avistep 2mg/100mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा लोपरामाइड और फ्यूराज़ोलिडोन का संयोजन है, जिसका उपयोग तीव्र संक्रामक दस्त के इलाज के लिए किया जाता है। यह आंतों की गति को धीमा करके और संक्रमण पैदा करने वाले बैक्टीरिया और परजीवियों को मारकर दस्त को कम करती है। यह दवा केवल डॉक्टर के परामर्श से ही लेनी चाहिए और खूनी दस्त, तेज बुखार, या 12 वर्ष से कम उम्र के बच्चों में नहीं देनी चाहिए। गर्भावस्था और स्तनपान के दौरान भी इसका उपयोग नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट में ऐंठन, सूखा मुँह, चक्कर आना और सिरदर्द शामिल हैं। कुछ लोगों को कब्ज या नींद आ सकती है। शराब के साथ लेने पर गंभीर प्रतिक्रिया हो सकती है जैसे चेहरे पर लालिमा, धड़कन तेज होना, मतली और उल्टी। दुर्लभ मामलों में गंभीर एलर्जी, रक्त विकार या तंत्रिका संबंधी समस्याएं हो सकती हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अधिक मात्रा में या लंबे समय तक न लें। शराब का सेवन पूरी तरह बंद कर दें, क्योंकि इससे गंभीर प्रतिक्रिया हो सकती है। खूनी दस्त, तेज बुखार या आंतों में रुकावट होने पर इसका उपयोग न करें। दस्त के दौरान ओआरएस का घोल पीते रहें ताकि शरीर में पानी और नमक की कमी न हो। चक्कर आने पर वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को बच्चों की पहुंच से दूर रखें।
💊 avistep 2mg/100mg capsule Uses & Benefits
[{"condition":"Acute infectious diarrhoea","description":"Used for short-term treatment of acute diarrhoea when bacterial or protozoal infection is suspected, helping to reduce stool frequency and relieve symptoms.","evidence":"Moderate"},{"condition":"Traveller's diarrhoea","description":"May be used to manage traveller's diarrhoea caused by susceptible organisms, but only under medical supervision.","evidence":"Limited"},{"condition":"Giardiasis","description":"Furazolidone component has activity against Giardia lamblia, but this combination is not first-line and should be used only if prescribed.","evidence":"Limited"}]
Off-label uses: []
Primary treatment for: Acute infectious diarrhoea
Also treats: Traveller's diarrhoea, Giardiasis
📋 Drug Information
| Generic Name(s) | Loperamide (2mg) + Furazolidone (100mg) |
| Brand Name | avistep 2mg/100mg capsule |
| Manufacturer | Bhavishya Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. This combination is not recommended by WHO for routine treatment of diarrhoea. Oral rehydration therapy and zinc are the mainstays for diarrhoea management. |
| ICMR Guideline | Not established from the available information. ICMR guidelines do not recommend this combination as first-line for acute diarrhoea. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Loperamide binds to opioid receptors in the gut wall, slowing intestinal motility and increasing anal sphincter tone, which reduces stool frequency and fluid loss. Furazolidone interferes with bacterial and protozoal enzyme systems, inhibiting their growth and multiplication. Together, they provide symptomatic relief and target susceptible gut pathogens.
Mechanism Steps
💡 How to Take avistep 2mg/100mg capsule
Strength: Capsule containing Loperamide 2 mg and Furazolidone 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule taken orally two to four times daily, as prescribed by your doctor. The exact dose and duration depend on the severity of diarrhoea, the causative organism, and your overall health. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially drowsiness and constipation. Use with caution and under medical supervision. Dose adjustment may be needed based on renal and hepatic function. |
| Renal Impairment | No specific dose adjustment data are available. Use with caution in patients with renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 8 mg of loperamide and 400 mg of furazolidone (four capsules per day). Do not exceed this unless directed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of avistep 2mg/100mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| MAO inhibitors | Major | |
| CYP3A4 inhibitors | Major | |
| Warfarin | Moderate | |
| Anticholinergics | Moderate | |
| CYP3A4 inducers | Moderate | |
| Antacids | Minor | |
| Laxatives | Minor |
🚨 Major Interactions
- Alcohol
- MAO inhibitors
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
⚡ Moderate Interactions
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
- Anticholinergic drugs
- Warfarin
🍷 Alcohol Interaction
Alcohol must be strictly avoided while taking this medicine and for at least 3 days after stopping. Furazolidone can cause a disulfiram-like reaction with alcohol, leading to flushing, severe nausea, vomiting, palpitations, and low blood pressure. This reaction can be dangerous and requires immediate medical attention if it occurs.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to loperamide, furazolidone, or any component","Bloody diarrhoea or suspected invasive bacterial infection","Acute ulcerative colitis","Bacterial enterocolitis caused by invasive organisms","Children under 12 years","Pregnancy and breastfeeding","Severe liver disease","Use with MAO inhibitors"]
⚠️ Warnings & Precautions
["Do not use for more than 2 days without medical advice.","Avoid alcohol completely during and for 3 days after treatment.","May cause drowsiness; avoid driving or operating machinery.","Stop use and consult doctor if diarrhoea persists beyond 48 hours.","Use with caution in elderly patients.","Not for use in children under 12 years.","May interact with many medicines; inform your doctor about all medications."]
🤱 Lactation Safety
Not established from the available information. It is not known whether loperamide or furazolidone passes into breast milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose may cause severe constipation, ileus, drowsiness, or respiratory depression due to loperamide. Seek immediate medical attention. Treatment is supportive and symptomatic. Naloxone may be used for loperamide toxicity. Do not induce vomiting unless advised by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Avoid alcohol completely while taking this medicine and for at least 3 days after stopping, as it can cause a severe reaction. Do not use this medicine for bloody diarrhoea, high fever, or if you have a history of bowel obstruction. Stay well hydrated with oral rehydration solutions to replace lost fluids and electrolytes. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Keep this medicine out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to dehydration, electrolyte imbalance, and side effects like drowsiness and constipation. Use with caution and monitor closely. Dose adjustment may be needed based on kidney and liver function.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for safe alternatives if you are trying to conceive or are pregnant.
🏥 Post-Surgery Considerations
Not established from the available information. Consult your surgeon before taking this medicine after surgery, as it may affect bowel movements.
🦷 Dental Procedures
Not established from the available information. Inform your dentist if you are taking this medicine before any dental procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while you have diarrhoea, as it can worsen dehydration. Light activity is fine once you feel better. Stay hydrated before, during, and after exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Take rest and stay hydrated to recover faster.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if diarrhoea persists beyond 48 hours, if you develop bloody stools, high fever, severe abdominal pain, or signs of an allergic reaction. Do not stop abruptly if you are on a prescribed course without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of loperamide can lead to dependence, severe constipation, and cardiac arrhythmias. Furazolidone may cause blood disorders and neurotoxicity with extended use. Use only for short-term treatment under medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Replaces lost fluids and electrolytes and is the cornerstone of diarrhoea management.
Evidence: Well-establishedRecommended in children with diarrhoea to reduce duration and severity.
Evidence: Well-establishedMay help restore gut flora and reduce duration of diarrhoea.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There are no specific vaccine interactions reported with this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue your regular dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines. Always carry oral rehydration salts as well.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Loperamide starts reducing diarrhoea within 1 to 2 hours. The antimicrobial effect of furazolidone takes longer, depending on the infection.
A: It can interact with several medicines, including MAO inhibitors, CYP3A4 inhibitors, and warfarin. Always inform your doctor about all medicines you are taking.
A: This medicine is not recommended during pregnancy unless clearly needed and prescribed by a doctor.
A: Take it as soon as you remember if less than half the dosing interval has passed. Otherwise, skip it and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of diarrhoea.
Fact: It is not suitable for bloody diarrhoea or diarrhoea with high fever, as it can worsen the condition. - Myth: It is safe to take alcohol with this medicine.
Fact: Alcohol can cause a severe disulfiram-like reaction with furazolidone and must be avoided. - Myth: This medicine can be given to children.
Fact: It is not recommended for children under 12 years due to safety concerns.