Asil Syrup - Uses, Price, Side Effects, and Dosage

4.5 (10 reviews)

Silymarin (NA)

🏭 Alpic Biotech Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is asil syrup used for?

Asil Syrup contains Silymarin, a hepatoprotective agent derived from milk thistle. It is used to treat liver disorders such as fatty liver, jaundice, and cirrhosis. Silymarin works by stabilizing liver cell membranes, promoting liver regeneration, and reducing inflammation. It is commonly prescribed for liver detoxification and to protect the liver from toxins.

Generic Name: Silymarin
Manufacturer: Alpic Biotech Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 asil syrup Uses & Benefits

Alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), drug-induced liver injury, viral hepatitis (as adjunct), cirrhosis, Amanita phalloides mushroom poisoning.

Off-label uses: Acne vulgaris, psoriasis, hyperlipidemia, diabetes mellitus, and as an adjuvant in cancer therapy.

📋 Drug Information

Generic Name(s)	Silymarin
Brand Name	Asil Syrup
Manufacturer	Alpic Biotech Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GASTRO INTESTINAL
Action Class	Hepatoprotectives
Route of Administration	Oral (syrup).
Storage	Store at room temperature (20-25°C), protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionPoorly absorbed orally; bioavailability is low due to extensive first-pass metabolism.

DistributionDistributes mainly to liver, kidneys, and intestines; crosses placenta.

Protein Binding80-90% bound to plasma proteins, mainly albumin.

MetabolismExtensively metabolized in the liver via conjugation (glucuronidation and sulfation); also undergoes enterohepatic recirculation.

Half-LifeApproximately 6-8 hours for silibinin, the major active component.

ExcretionPrimarily excreted in bile (80%) and feces; about 10% excreted in urine.

BioavailabilityLow (23-47%) due to poor absorption and first-pass metabolism.

Onset of ActionNot well-defined; effects on liver enzymes may take days to weeks.

Peak Plasma Time1-2 hours after oral administration.

Duration of ActionNot well-defined; hepatoprotective effects may persist for several hours.

How It Works

Antioxidant, anti-inflammatory, antifibrotic; inhibits lipid peroxidation, stabilizes hepatocyte membranes, stimulates protein synthesis, and modulates immune response.

Mechanism Steps

1Scavenges free radicals and reactive oxygen species, reducing oxidative stress.

2Inhibits lipid peroxidation in hepatocyte membranes.

3Stabilizes hepatocyte membranes by preventing loss of glutathione.

💡 How to Take asil syrup

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of asil syrup

✅ Common Side Effects

Nausea
Diarrhea
Bloating
Dyspepsia
Headache
Skin rash

🚨 Serious Side Effects

Allergic reaction (anaphylaxis)
Severe skin reactions (Stevens-Johnson syndrome)
Hepatitis (rare)

⚠️ Rare Side Effects

Interstitial nephritis
Thyroid dysfunction
Gynecomastia (due to weak estrogenic activity)

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Moderate	May decrease anticoagulant effect
Oral Contraceptives	Minor	May reduce effectiveness of silymarin

🚨 Major Interactions

Warfarin
Indinavir
Ritonavir
Metronidazole
Cisplatin

⚡ Moderate Interactions

Oral contraceptives
Statins (e.g., atorvastatin)
Benzodiazepines (e.g., diazepam)
Losartan
Tacrolimus

ℹ️ Minor Interactions

Caffeine
Theophylline
Alcohol

🍽️ Food Interactions

Grapefruit juice may increase absorption; high-fat meals may decrease absorption.

🍷 Alcohol Interaction

May reduce alcohol-induced hepatotoxicity; concurrent use may alter metabolism of alcohol.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to silymarin or any component; caution in patients with hormone-sensitive cancers due to weak estrogenic activity.

📊 Monitoring Parameters

Liver function tests (ALT, AST, bilirubin), renal function, and prothrombin time if on warfarin.

🤱 Lactation Safety

Excreted in breast milk in small amounts; generally considered safe but consult physician.

💊 Overdose Management

No specific antidote; symptomatic and supportive care; induce vomiting or gastric lavage if recent ingestion.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for asil syrup

View All

Alternative brands with exact same active ingredient (Silymarin (NA)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.