apred 5mg tablet - Prednisolone (5mg) medicine

Apred 5mg Tablet - Uses, Price, Side Effects

4.7 (19 reviews)

Prednisolone (5mg)

🏭 Acron Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is apred 5mg tablet used for?

Apred 5mg Tablet contains Prednisolone, a corticosteroid that reduces inflammation and suppresses the immune system. It is used to treat conditions like allergies, asthma, rheumatoid arthritis, and skin disorders. It works by blocking the release of substances that cause inflammation.

Generic Name: Prednisolone
Manufacturer: Acron Pharmaceuticals
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 apred 5mg tablet Uses & Benefits

Allergic conditions, Asthma, Rheumatoid arthritis, Inflammatory bowel disease, Ophthalmic inflammation, Otological inflammation

Off-label uses: COVID-19 (severe cases), Acute respiratory distress syndrome, Adrenal insufficiency (off-label dosing)

📋 Drug Information

Generic Name(s)	Prednisolone
Brand Name	Acticort 10mg Tablet
Manufacturer	Acron Pharmaceuticals
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	OPHTHAL OTOLOGICALS
Action Class	Glucocorticoids
Route of Administration	Oral
Storage	Store at room temperature (20-25°C), protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract after oral administration.

DistributionWidely distributed into tissues; crosses placenta and enters breast milk.

Protein Binding70-90% bound to corticosteroid-binding globulin and albumin.

MetabolismHepatic metabolism primarily via CYP3A4 to inactive metabolites.

Half-Life2-4 hours (plasma half-life); biological half-life 18-36 hours.

ExcretionRenal excretion of metabolites; less than 1% unchanged drug.

Bioavailability70-90% after oral administration.

Onset of ActionWithin 1-2 hours for anti-inflammatory effects.

Peak Plasma Time1-2 hours after oral dose.

Duration of Action18-36 hours (biological effects).

How It Works

Binds to glucocorticoid receptors, modulating gene expression to reduce inflammation and immune response.

Mechanism Steps

1Prednisolone diffuses across cell membrane and binds to glucocorticoid receptor (GR) in cytoplasm.

2Receptor-ligand complex translocates to nucleus and binds to glucocorticoid response elements (GREs) on DNA.

3Modulates gene transcription: increases anti-inflammatory proteins (e.g., lipocortin-1) and decreases pro-inflammatory cytokines (e.g., IL-1, TNF-α).

💡 How to Take apred 5mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of apred 5mg tablet

✅ Common Side Effects

Increased appetite
Weight gain
Insomnia
Mood changes
Fluid retention
Hypertension
Hyperglycemia

🚨 Serious Side Effects

Adrenal suppression
Osteoporosis
Peptic ulcer
Pancreatitis
Psychiatric disturbances
Increased infection risk

⚠️ Rare Side Effects

Avascular necrosis of femoral head
Cushing's syndrome
Glaucoma
Cataracts
Thromboembolism

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Aspirin	Moderate	Increased gastrointestinal ulcer risk
Phenytoin	Moderate	Decreased phenytoin levels

🚨 Major Interactions

Warfarin
CYP3A4 inducers (e.g., rifampin)
CYP3A4 inhibitors (e.g., ketoconazole)
NSAIDs
Antidiabetic agents

⚡ Moderate Interactions

Diuretics
Amphotericin B
Vaccines (live attenuated)
Anticholinesterases

ℹ️ Minor Interactions

Oral contraceptives
Estrogens
Antacids

🍽️ Food Interactions

Grapefruit juice may increase levels; avoid high sodium foods.

🍷 Alcohol Interaction

May increase risk of gastrointestinal bleeding; avoid concurrent use.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Systemic fungal infections, Hypersensitivity to prednisolone, Live virus vaccination, Peptic ulcer disease (relative)

📊 Monitoring Parameters

Blood glucose, Blood pressure, Serum potassium, Bone density (long-term), Ophthalmic exam (long-term)

🤱 Lactation Safety

Excreted in breast milk; caution advised; use only if clearly needed.

💊 Overdose Management

No specific antidote; supportive care; monitor electrolytes and glucose.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for apred 5mg tablet

View All

Alternative brands with exact same active ingredient (Prednisolone (5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.