anihist syrup - Bromhexine (2mg) + Guaifenesin (50mg) medicine

Anihist Syrup: Complete Guide to Uses, Dosage, and Safety

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🏭 Anikem Laboratories 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for common uses; limited for off-label uses.
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or shortness of breath
  • Swelling of the face, lips, tongue, or throat
  • Severe rash, itching, or hives
  • Chest pain or fast heartbeat
  • Coughing up blood
  • High fever with chills
  • Symptoms lasting more than 7 days or worsening

If experiencing severe symptoms, call emergency services immediately.

What is anihist syrup used for?

This medicine is a combination of bromhexine and guaifenesin, used to treat productive cough by loosening mucus and making it easier to cough out. It is taken orally as a syrup, usually 5-10 mL three to four times a day for adults, but follow your doctor's advice.

  • Generic Name: Bromhexine + Guaifenesin
  • Manufacturer: Anikem Laboratories
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 anihist syrup के बारे में (Hindi Summary)

उपयोग: यह दवा ब्रोमहेक्सिन और गुआइफेनेसिन का संयोजन है, जिसका उपयोग कफ और बलगम को ढीला करने और बाहर निकालने में मदद करने के लिए किया जाता है। यह गीली खांसी, छाती में जकड़न और बलगम वाली खांसी के लिए प्रभावी है। यह बलगम को पतला करती है जिससे खांसी आसानी से आती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट खराब, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको एलर्जी, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर गंभीर दाने हों तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अधिक मात्रा में न लें। दवा लेते समय खूब पानी पिएं। यदि आपको चक्कर या नींद आती है तो वाहन चलाने या मशीन चलाने से बचें। सूखी खांसी के लिए इस दवा का उपयोग न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 anihist syrup Uses & Benefits

[{"condition":"Productive cough (wet cough)","description":"Helps loosen thick mucus in the airways, making it easier to cough out and relieving chest congestion.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Used to reduce mucus viscosity and improve clearance in acute inflammation of the bronchi.","evidence":"Moderate"},{"condition":"Chronic bronchitis","description":"May help manage chronic mucus hypersecretion and improve symptoms in chronic bronchitis.","evidence":"Moderate"},{"condition":"COPD (chronic obstructive pulmonary disease)","description":"Sometimes used as an adjunct to help with mucus clearance in COPD patients with thick secretions.","evidence":"Limited"}]

Off-label uses: [{"condition":"Sinusitis","description":"May be used off-label to help thin mucus in sinus congestion, but evidence is limited.","evidence":"Limited"},{"condition":"Otitis media with effusion","description":"Occasionally used off-label to help clear middle ear fluid, but not routinely recommended.","evidence":"Limited"}]

Primary treatment for: Productive cough

Also treats: Acute bronchitis, Chronic bronchitis, COPD

📋 Drug Information

Generic Name(s)Bromhexine + Guaifenesin
Brand NameAscoril Plus Expectorant
ManufacturerAnikem Laboratories
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic and Expectorant
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture, unless otherwise stated on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or a snack to reduce the chance of stomach upset.
2
Drink plenty of water throughout the day to help loosen mucus and make coughing more productive.
3
Do not use this medicine for a dry cough or for more than 7 days without consulting a doctor.
4
Avoid driving or operating heavy machinery if you feel dizzy or drowsy after taking this medicine.
5
Do not combine this medicine with cough suppressants unless specifically told to do so by your doctor.
6
If you are pregnant, breastfeeding, or have kidney or liver disease, consult your doctor before using this medicine.
7
Keep track of your symptoms and inform your doctor if they do not improve or worsen.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not effective for dry cough and may be harmful.
Not Primary
✅
Chest congestion
This medicine helps loosen mucus and relieve congestion.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionNot established from the available information.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine combines two active ingredients with complementary actions. Bromhexine is a mucolytic that breaks down the structure of mucus by depolymerizing mucopolysaccharide fibers, reducing mucus viscosity. Guaifenesin is an expectorant that increases the volume and reduces the viscosity of secretions in the respiratory tract, likely by stimulating gastric reflexes and increasing water content in mucus. Together, they make cough more productive and help clear airways.

Mechanism Steps

1
Bromhexine breaks down mucus structure: Bromhexine depolymerizes mucopolysaccharide fibers in mucus, reducing its thickness and stickiness.
2
Guaifenesin increases mucus water content: Guaifenesin stimulates secretions and increases hydration of mucus, making it less viscous.
3
Enhanced mucociliary clearance: The combined effect allows cilia in the airways to move loosened mucus more effectively toward the throat for expulsion.
4
Productive cough: The loosened mucus is coughed out more easily, relieving chest congestion.

💡 How to Take anihist syrup

Strength: Each 5 mL of syrup contains bromhexine 2 mg and guaifenesin 50 mg.

1Shake the bottle well before each use.
2Use a measuring cup or spoon provided with the medicine to measure the correct dose.
3Take the medicine orally, with or without food. If it upsets your stomach, take it with a meal or snack.
4Drink a glass of water after taking the medicine to help loosen mucus.
5Do not take more than the recommended dose.
6Wash the measuring cup after each use.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5-10 mL (one to two teaspoons) taken three to four times a day, or as directed by your doctor. The dose may vary depending on the severity of your condition and your response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, such as dizziness and drowsiness. Use with caution and follow your doctor's advice. Dose adjustment may be needed based on kidney and liver function.
Renal ImpairmentNo specific dose adjustment guidelines are available for patients with kidney disease. Consult your doctor for appropriate dosing.
Hepatic ImpairmentNo specific dose adjustment guidelines are available for patients with liver disease. Consult your doctor for appropriate dosing.
Maximum Daily DoseThe maximum daily dose should not exceed the amount recommended by your doctor. Typically, do not exceed 40 mL (8 teaspoons) in 24 hours for adults, but this may vary. Always follow your doctor's instructions.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals or snacks
Reduces stomach upset and nausea.
Water
Drink plenty of water
Helps loosen mucus and makes coughing more productive.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of anihist syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated with small sips of water. If vomiting is severe or persistent, contact your doctor.
Diarrhea (Common (5-10%))
Drink plenty of fluids to prevent dehydration. If diarrhea lasts more than 2 days, consult your doctor.
Stomach upset (Common (5-10%))
Take the medicine with a meal or snack. Avoid spicy foods.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you feel normal. If dizziness persists, consult your doctor.
Drowsiness (Uncommon (1-5%))
Avoid activities requiring alertness. If drowsiness is bothersome, talk to your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical help if you experience rash, itching, swelling of face, lips, or throat, or difficulty breathing.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Rare (<0.1%))
Stop the medicine and seek immediate medical attention if you develop a severe rash with blisters or peeling skin.
Kidney problems (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.

⚠️ Rare Side Effects

Blood disorders (e.g., thrombocytopenia)
Seek medical attention if you notice unusual bleeding or bruising.
Liver enzyme elevation
Report yellowing of skin or eyes, dark urine, or abdominal pain to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Codeine Major
Dextromethorphan Major
Amoxicillin Moderate
Cefuroxime Moderate
Atropine Moderate
Hyoscyamine Moderate
Furosemide Minor

🚨 Major Interactions

  • Cough suppressants (e.g., codeine, dextromethorphan)

⚡ Moderate Interactions

  • Antibiotics (e.g., amoxicillin, cefuroxime)
  • Anticholinergic drugs (e.g., atropine, hyoscyamine)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and stomach upset while taking this medicine. It is best to avoid alcohol during treatment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity or allergy to bromhexine, guaifenesin, or any component of the formulation","Children under the age recommended by the manufacturer or doctor (typically under 2 years, but consult a pediatrician)","Use in patients with severe liver or kidney impairment without medical supervision"]

⚠️ Warnings & Precautions

["Do not use for a dry cough or for cough lasting more than 7 days without medical advice.","Drink plenty of water to help loosen mucus.","Avoid driving or operating machinery if you experience dizziness or drowsiness.","Consult a doctor before use if you have a history of kidney or liver disease.","Do not exceed the recommended dose.","Keep out of reach of children.","If symptoms worsen or do not improve, seek medical advice."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

If you suspect an overdose, seek immediate medical attention or contact a poison control center. Symptoms of overdose may include severe nausea, vomiting, diarrhea, and dizziness. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose. Drink plenty of water while taking this medicine to help loosen mucus. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Do not use this medicine for a dry cough or for more than the recommended duration without consulting a doctor. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of reach of children. Do not use it after the expiry date. If your symptoms do not improve within a few days or if they worsen, contact your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. They may also have reduced kidney or liver function, which can affect drug clearance. Use with caution and follow your doctor's advice.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this medicine during pregnancy is not well established, and it should only be used if clearly needed.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before using this medicine. It may interact with other medications or affect recovery. Do not self-medicate.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It is generally safe, but your dentist may want to know about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of water and warm fluids.
🥗
Use a humidifier or take steamy showers to help loosen mucus.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to help your body recover.
🧘
Avoid cold drinks and icy foods that can worsen cough.
🌞
Practice good hand hygiene to prevent infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have a cough or difficulty breathing. Light activity like walking is fine if you feel up to it. If you experience dizziness or shortness of breath, stop and rest.

🥗 Diet Recommendations

Drink warm fluids like herbal tea, soup, and warm water with honey.
Include foods rich in vitamin C (citrus fruits, bell peppers) to support immunity.
Avoid dairy products if they seem to thicken mucus for you.
Eat light, easily digestible meals.
Avoid spicy and oily foods that can irritate the throat.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. If affected, avoid driving, operating machinery, or performing tasks that require alertness. Otherwise, it should not significantly impact your daily activities. Take it as prescribed and rest when needed.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your cough does not improve within 7 days, if it worsens, or if you experience any severe side effects. Do not stop abruptly if you have been on it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to unnecessary side effects and may mask underlying conditions. If you need to use it for more than 7 days, consult your doctor to determine the cause of your cough and appropriate treatment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Inhaling steam can help loosen mucus and relieve congestion.

Evidence: Well-established
Saline nasal irrigation

Using saline sprays or rinses can help clear nasal passages and reduce postnasal drip.

Evidence: Moderate
Honey and warm fluids

Honey can soothe the throat and warm fluids help thin mucus.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccination, inform your healthcare provider that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container with cap tightly closed

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, continue taking the medicine at your usual intervals, but adjust as advised by your doctor. Do not leave it in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He had a persistent wet cough with thick mucus for several days. His doctor prescribed this medicine. After taking it for 3 days, he noticed that his cough became more productive and his chest felt less congested. He made sure to drink plenty of water and took the syrup with meals to avoid stomach upset.
💡 Lesson: Taking this medicine as prescribed and staying hydrated can significantly improve mucus clearance and relieve chest congestion.
👤 A 60-year-old woman with chronic bronchitis
She experienced frequent episodes of thick mucus and difficulty breathing. Her doctor added this medicine to her treatment plan. She found that it helped loosen the mucus, making it easier to cough out. She also used a humidifier at home and avoided cold drinks.
💡 Lesson: This medicine can be helpful in chronic conditions when used as part of a comprehensive treatment plan, including lifestyle measures.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts to loosen mucus within a few hours, but noticeable relief may take 1-2 days. If symptoms persist beyond 7 days, consult your doctor.

Q: Can I take this medicine for dry cough?

A: No, this medicine is for productive (wet) cough with mucus. It is not effective for dry cough and may be harmful if used incorrectly.

Q: Is it safe to take with antibiotics?

A: Bromhexine may increase the concentration of some antibiotics in lung tissue, which can be beneficial. However, always inform your doctor about all medicines you are taking.

Q: Can I take this medicine during pregnancy?

A: Consult your doctor before using this medicine if you are pregnant or planning to become pregnant. The safety profile is not well established.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe for children?
  • Can I take it with antibiotics?

🔄 Substitutes for anihist syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is only for productive (wet) cough with mucus. It is not effective for dry cough and may be harmful if used incorrectly.
  • Myth: More syrup means faster relief.
    Fact: Taking more than the recommended dose does not speed up recovery and can increase side effects. Always follow the prescribed dose.
  • Myth: It is safe to take this medicine with any other cough medicine.
    Fact: Combining with cough suppressants can be dangerous as it may lead to mucus buildup. Always consult a doctor before combining medicines.

🔄 Alternative Options

Generic Alternatives

  • Bromhexine + Guaifenesin syrup (generic)

Brand Alternatives

  • Anihist Syrup

📊 Comparison with Similar Medicines

[{"medicine":"Anihist Syrup","active_ingredients":"Bromhexine 2mg + Guaifenesin 50mg","primary_use":"Productive cough","route":"Oral"},{"medicine":"Ambroxol + Guaifenesin","active_ingredients":"Ambroxol + Guaifenesin","primary_use":"Productive cough","route":"Oral"},{"medicine":"Bromhexine + Dextromethorphan","active_ingredients":"Bromhexine + Dextromethorphan","primary_use":"Cough (mixed)","route":"Oral"}]

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