breath syrup - Bromhexine (2mg) + Salbutamol (1mg) medicine

Breath Syrup - Uses, Price, Side Effects

4.5 (18 reviews)
๐Ÿญ Hippo Labs Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is breath syrup used for?

Breath Syrup contains Bromhexine (2mg) and Salbutamol (1mg). Bromhexine is an expectorant that thins mucus, making it easier to cough up, while Salbutamol is a bronchodilator that relaxes airway muscles to relieve wheezing and breathlessness. It is used for cough with phlegm and respiratory conditions like asthma and bronchitis.

  • Generic Name: Bromhexine + Salbutamol
  • Manufacturer: Hippo Labs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š breath syrup Uses & Benefits

Bronchial asthma, Chronic bronchitis, COPD, Mucolytic therapy

Off-label uses: Cystic fibrosis, Bronchiectasis

๐Ÿ“‹ Drug Information

Generic Name(s)Bromhexine + Salbutamol
Brand NameAsmatide BR 8 mg/4 mg/200 mg Tablet
ManufacturerHippo Labs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Bronchodilator
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionBromhexine: Rapidly absorbed from GI tract; Salbutamol: Well absorbed after oral administration.
DistributionBromhexine: Widely distributed; Salbutamol: Crosses placenta, distributed to breast milk.
Protein BindingBromhexine: 90-99%; Salbutamol: 10-15%.
MetabolismBromhexine: Hepatic via CYP450; Salbutamol: Hepatic via conjugation.
Half-LifeBromhexine: 12-24 hours; Salbutamol: 4-6 hours.
ExcretionBromhexine: Renal (70% as metabolites); Salbutamol: Renal (60-70% unchanged and metabolites).
BioavailabilityBromhexine: 75-80%; Salbutamol: 50-60%.
Onset of ActionBromhexine: 1-2 hours; Salbutamol: 30 minutes.
Peak Plasma TimeBromhexine: 1-2 hours; Salbutamol: 2-3 hours.
Duration of ActionBromhexine: 6-8 hours; Salbutamol: 4-6 hours.

How It Works

Bromhexine increases respiratory tract secretions and reduces mucus viscosity; Salbutamol stimulates beta-2 adrenergic receptors causing bronchodilation.

Mechanism Steps

1Bromhexine stimulates secretion of respiratory tract fluid and reduces mucus viscosity.
2Salbutamol selectively binds to beta-2 adrenergic receptors on bronchial smooth muscle.
3Activation of adenylate cyclase increases intracellular cAMP.

๐Ÿ’ก How to Take breath syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of breath syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Tremor
  • Palpitations

๐Ÿšจ Serious Side Effects

  • Hypokalemia
  • Cardiac arrhythmias
  • Paradoxical bronchospasm
  • Hypersensitivity reactions

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Nephrotoxicity
  • Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Beta-blockers Moderate May reduce bronchodilator effect
MAOIs Major Increased risk of hypertensive crisis
Diuretics Moderate Hypokalemia risk

๐Ÿšจ Major Interactions

  • MAOIs
  • Tricyclic antidepressants
  • Beta-blockers
  • Diuretics
  • Digoxin

โšก Moderate Interactions

  • Corticosteroids
  • Xanthine derivatives
  • Anticholinergics

โ„น๏ธ Minor Interactions

  • Antihistamines
  • Decongestants

๐Ÿฝ๏ธ Food Interactions

No significant food interactions reported.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS depression.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Moderate
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, Cardiac arrhythmias, Hypertension, Hyperthyroidism, Pheochromocytoma

๐Ÿ“Š Monitoring Parameters

Respiratory function, Heart rate, Blood pressure, Serum potassium

๐Ÿคฑ Lactation Safety

Caution; Salbutamol excreted in breast milk.

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, supportive care; monitor cardiac function and electrolytes.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

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