breath syrup - Bromhexine (2mg) + Salbutamol (1mg) medicine

Breath Syrup - Uses, Price, Side Effects

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🏭 Hippo Labs Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
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What is breath syrup used for?

Breath Syrup contains Bromhexine (2mg) and Salbutamol (1mg). Bromhexine is an expectorant that thins mucus, making it easier to cough up, while Salbutamol is a bronchodilator that relaxes airway muscles to relieve wheezing and breathlessness. It is used for cough with phlegm and respiratory conditions like asthma and bronchitis.

  • Generic Name: Bromhexine + Salbutamol
  • Manufacturer: Hippo Labs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 breath syrup Uses & Benefits

Bronchial asthma, Chronic bronchitis, COPD, Mucolytic therapy

Off-label uses: Cystic fibrosis, Bronchiectasis

📋 Drug Information

Generic Name(s)Bromhexine + Salbutamol
Brand NameAsmatide BR 8 mg/4 mg/200 mg Tablet
ManufacturerHippo Labs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Bronchodilator
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBromhexine: Rapidly absorbed from GI tract; Salbutamol: Well absorbed after oral administration.
DistributionBromhexine: Widely distributed; Salbutamol: Crosses placenta, distributed to breast milk.
Protein BindingBromhexine: 90-99%; Salbutamol: 10-15%.
MetabolismBromhexine: Hepatic via CYP450; Salbutamol: Hepatic via conjugation.
Half-LifeBromhexine: 12-24 hours; Salbutamol: 4-6 hours.
ExcretionBromhexine: Renal (70% as metabolites); Salbutamol: Renal (60-70% unchanged and metabolites).
BioavailabilityBromhexine: 75-80%; Salbutamol: 50-60%.
Onset of ActionBromhexine: 1-2 hours; Salbutamol: 30 minutes.
Peak Plasma TimeBromhexine: 1-2 hours; Salbutamol: 2-3 hours.
Duration of ActionBromhexine: 6-8 hours; Salbutamol: 4-6 hours.

How It Works

Bromhexine increases respiratory tract secretions and reduces mucus viscosity; Salbutamol stimulates beta-2 adrenergic receptors causing bronchodilation.

Mechanism Steps

1Bromhexine stimulates secretion of respiratory tract fluid and reduces mucus viscosity.
2Salbutamol selectively binds to beta-2 adrenergic receptors on bronchial smooth muscle.
3Activation of adenylate cyclase increases intracellular cAMP.
4cAMP relaxes bronchial smooth muscle and inhibits mediator release.
5Combined effect improves mucociliary clearance and bronchodilation.

💡 How to Take breath syrup

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of breath syrup

✅ Common Side Effects

Nausea
Vomiting
Diarrhea
Headache
Tremor
Palpitations

🚨 Serious Side Effects

Hypokalemia
Cardiac arrhythmias
Paradoxical bronchospasm
Hypersensitivity reactions

⚠️ Rare Side Effects

Hepatotoxicity
Nephrotoxicity
Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Beta-blockers Moderate May reduce bronchodilator effect
MAOIs Major Increased risk of hypertensive crisis
Diuretics Moderate Hypokalemia risk

🚨 Major Interactions

  • MAOIs
  • Tricyclic antidepressants
  • Beta-blockers
  • Diuretics
  • Digoxin

⚡ Moderate Interactions

  • Corticosteroids
  • Xanthine derivatives
  • Anticholinergics

🍷 Alcohol Interaction

Avoid alcohol; may increase CNS depression.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, Cardiac arrhythmias, Hypertension, Hyperthyroidism, Pheochromocytoma

🤱 Lactation Safety

Caution; Salbutamol excreted in breast milk.

💊 Overdose Management

Gastric lavage, activated charcoal, supportive care; monitor cardiac function and electrolytes.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

🔄 Substitutes for breath syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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