anescaine 2% gel - Lidocaine (2%) medicine

anescaine 2% gel - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Vhb Life Sciences Inc ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is anescaine 2% gel used for?

Anas Dee Gel (Lidocaine) is used to treat PAIN ANALGESICS. It contains Lidocaine (2%), which Blocks voltage-gated sodium channels, inhibiting neuronal depolarization and pai. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Lidocaine
  • Manufacturer: Vhb Life Sciences Inc
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š anescaine 2% gel Uses & Benefits

Topical anesthesia for minor procedures, relief of pain from hemorrhoids, sunburn, insect bites, and oral ulcers.

Off-label uses: Post-herpetic neuralgia, premature ejaculation (topical).

๐Ÿ“‹ Drug Information

Generic Name(s)Lidocaine
Brand NameAnas Dee Gel
ManufacturerVhb Life Sciences Inc
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassLocal anaesthetic (Amides)
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed through mucous membranes and damaged skin.
DistributionWidely distributed; crosses blood-brain barrier and placenta.
Protein Binding60-80% bound to plasma proteins, mainly alpha-1-acid glycoprotein.
MetabolismHepatic metabolism via CYP1A2 and CYP3A4 to active metabolites (MEGX, GX).
Half-Life1.5-2 hours (prolonged in hepatic impairment).
ExcretionRenal excretion of metabolites (<10% unchanged).
BioavailabilityLow oral bioavailability due to first-pass metabolism; topical absorption variable.
Onset of Action2-5 minutes
Peak Plasma Time30-60 minutes (topical)
Duration of Action30-60 minutes (topical)

How It Works

Blocks voltage-gated sodium channels, inhibiting neuronal depolarization and pain transmission.

Mechanism Steps

1Lidocaine diffuses across the nerve cell membrane.
2Binds to the intracellular portion of voltage-gated sodium channels.
3Blocks sodium influx, preventing depolarization.

๐Ÿ’ก How to Take anescaine 2% gel

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of anescaine 2% gel

โœ… Common Side Effects

  • Local irritation
  • Erythema
  • Edema
  • Burning sensation

๐Ÿšจ Serious Side Effects

  • Seizures
  • Cardiac arrhythmias
  • Hypotension
  • Respiratory depression

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Methemoglobinemia
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Amiodarone Major Increased risk of cardiac toxicity
Cimetidine Major Increased lidocaine levels
Propranolol Moderate Reduced lidocaine clearance
Grapefruit juice Minor Increased lidocaine absorption

๐Ÿšจ Major Interactions

  • Class III antiarrhythmics
  • CYP1A2 inhibitors (e.g., cimetidine)
  • CYP3A4 inhibitors (e.g., ketoconazole)

โšก Moderate Interactions

  • Beta-blockers
  • Other local anesthetics
  • Succinylcholine

โ„น๏ธ Minor Interactions

  • Antacids
  • Ranitidine

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase lidocaine levels.

๐Ÿท Alcohol Interaction

May enhance CNS depression.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to lidocaine or amide anesthetics, severe heart block, Adams-Stokes syndrome, porphyria.

๐Ÿ“Š Monitoring Parameters

Monitor for signs of systemic toxicity (dizziness, tinnitus, seizures, arrhythmias).

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; generally considered safe.

๐Ÿ’Š Overdose Management

Supportive care; benzodiazepines for seizures; lipid emulsion therapy for severe toxicity.

โฐ Missed Dose

Apply as needed; do not exceed recommended frequency.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for anescaine 2% gel

View All

Alternative brands with exact same active ingredient (Lidocaine (2%)):

Medical Note: Always consult your doctor before switching medications.

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