artamin 250mg capsule allopathy (Penicillamine (250mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
artamin 250mg capsule allopathy (Penicillamine (250mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Vhb Life Sciences Inc. Contains Penicillamine (250mg).

artamin 250mg capsule - Uses, Price, Side Effects & Substitutes

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Penicillamine (250mg) (Click to see all medicines with same salt)
🏭 Vhb Life Sciences Inc 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is artamin 250mg capsule used for?

Artamin (Penicillamine) is used to treat Rheumatoid arthritis. It contains Penicillamine (250mg), which Chelates heavy metals, reduces sulfhydryl groups, and inhibits collagen cross-li. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Penicillamine
  • Manufacturer: Vhb Life Sciences Inc
  • Medicine Form: Allopathy
  • Pregnancy Category: D

🇮🇳 artamin 250mg capsule के बारे में संक्षिप्त जानकारी (Hindi Summary)

artamin 250mg capsule का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Penicillamine (250mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Artamin 250mg Capsule is used in the treatment of rheumatoid arthritis and Wilson's disease. It slows the progression of rheumatoid arthritis and prov... Read more below.

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

📋 Drug Information

Generic Name(s)Penicillamine
Brand NameArtamin
ManufacturerVhb Life Sciences Inc
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassDisease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally, approximately 40-70% absorbed from the gastrointestinal tract.
DistributionDistributes widely into body tissues and fluids, including synovial fluid.
Protein BindingApproximately 80% bound to plasma proteins, mainly albumin.
MetabolismExtensively metabolized in the liver to disulfide metabolites.
Half-Life1.5-2 hours, but may be prolonged in renal impairment.
ExcretionPrimarily excreted in urine as metabolites and unchanged drug.
Bioavailability40-70%
Onset of ActionSeveral weeks to months for therapeutic effect in rheumatoid arthritis.
Peak Plasma Time1-2 hours
Duration of ActionNot well defined; effects persist with continued dosing.

Pharmacodynamics

Mechanism of ActionChelates heavy metals, reduces sulfhydryl groups, and inhibits collagen cross-linking; in rheumatoid arthritis, it may suppress immune complex formation and reduce rheumatoid factor.
Target ReceptorNot a specific receptor; acts as a chelating agent and immunomodulator.
Pharmacodynamic EffectsReduces rheumatoid factor, immune complexes, and inflammatory markers; promotes urinary excretion of copper and other heavy metals.

💡 How and when to take artamin 250mg capsule?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from light and moisture.

⚙️ How artamin 250mg capsule Works

Chelates heavy metals, reduces sulfhydryl groups, and inhibits collagen cross-linking; in rheumatoid arthritis, it may suppress immune complex formation and reduce rheumatoid factor.

1 Chelates heavy metals (e.g., copper, mercury, lead) forming soluble complexes excreted in urine.
⬇️
2 Reduces disulfide bonds in collagen, inhibiting cross-linking and reducing fibrosis.
⬇️
3 Suppresses immune complex formation and reduces rheumatoid factor in rheumatoid arthritis.
⬇️
4 Inhibits T-cell function and reduces inflammatory cytokine production.

💊 artamin 250mg capsule Uses in Hindi (Ke Fayde), Benefits & Indications

Rheumatoid arthritis, Wilson's disease, cystinuria, heavy metal poisoning.

Off-label uses: Scleroderma, primary biliary cirrhosis, psoriasis.

⚠️ What are the side effects of artamin 250mg capsule?

✅ Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Anorexia
  • Loss of taste
  • Rash
  • Oral ulcers

🚨 Serious Side Effects

  • Bone marrow suppression (agranulocytosis, aplastic anemia)
  • Proteinuria
  • Nephrotic syndrome
  • Myasthenia gravis-like syndrome
  • Goodpasture's syndrome
  • Systemic lupus erythematosus

⚠️ Rare Side Effects

  • Hepatotoxicity
  • Pancreatitis
  • Peripheral neuropathy
  • Thrombocytopenia
  • Leukopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Gold compounds Major Increased risk of hematologic and renal toxicity
Antimalarials Major Additive immunosuppression
Immunosuppressants Major Increased risk of infection and bone marrow suppression
Cytotoxic drugs Major Enhanced toxicity
Iron supplements Moderate Reduced absorption of penicillamine
Digoxin Moderate Possible decreased digoxin levels
Antacids Moderate Reduced absorption of penicillamine
Zinc supplements Minor Reduced absorption of penicillamine
Vitamin B6 Minor May counteract penicillamine-induced pyridoxine deficiency

🚨 Major Interactions

  • Gold compounds
  • Antimalarials
  • Immunosuppressants
  • Cytotoxic drugs

⚡ Moderate Interactions

  • Iron supplements
  • Digoxin
  • Antacids

ℹ️ Minor Interactions

  • Zinc supplements
  • Vitamin B6

🍽️ Food Interactions

Food reduces absorption; take on empty stomach.

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to penicillamine, history of agranulocytosis or aplastic anemia, severe renal insufficiency, pregnancy.

📊 Monitoring Parameters

Complete blood count, urinalysis, liver function tests, renal function tests, and skin examination.

🤱 Lactation Safety

Contraindicated; excreted in breast milk.

💊 Overdose Management

Induce emesis or gastric lavage; administer activated charcoal; monitor for bone marrow suppression and renal function.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🛑 Myths vs. Facts about artamin 250mg capsule

  • Myth: Generic substitutes of artamin 250mg capsule are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Penicillamine (250mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of artamin 250mg capsule can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

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