Azoprine 50mg Tablet - Uses, Price, Side Effects
What is azoprine 50mg tablet used for?
Azoprine 50mg Tablet contains Azathioprine, an immunosuppressant that works by inhibiting DNA synthesis in rapidly dividing cells, thereby suppressing the immune system. It is primarily used to prevent organ transplant rejection and to treat autoimmune diseases such as rheumatoid arthritis and lupus.
- Generic Name: Azathioprine
- Manufacturer: Vhb Life Sciences Inc
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ azoprine 50mg tablet Uses & Benefits
Prevention of organ transplant rejection, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease (Crohn's disease, ulcerative colitis), autoimmune hepatitis.
Off-label uses: Behรงet's disease, myasthenia gravis, pemphigus vulgaris, atopic dermatitis, multiple sclerosis.
๐ Drug Information
| Generic Name(s) | Azathioprine |
| Brand Name | Azoran Tablet |
| Manufacturer | Vhb Life Sciences Inc |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Immunosuppressant- Purine analogs |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Azathioprine is a purine analog that inhibits DNA and RNA synthesis, suppressing immune cell proliferation.
Mechanism Steps
๐ก How to Take azoprine 50mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of azoprine 50mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Leukopenia
- Anemia
- Thrombocytopenia
- Increased liver enzymes
๐จ Serious Side Effects
- Severe bone marrow suppression
- Hepatotoxicity
- Pancreatitis
- Serious infections
- Lymphoma
- Skin cancer
โ ๏ธ Rare Side Effects
- Pulmonary fibrosis
- Venocclusive disease of liver
- Alopecia
- Rash
- Arthralgia
- Hypersensitivity reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Allopurinol | Major | Increased azathioprine toxicity |
| Ribavirin | Major | Increased myelosuppression |
๐จ Major Interactions
- Allopurinol
- Warfarin
- Ribavirin
- Febuxostat
- Co-trimoxazole
โก Moderate Interactions
- ACE inhibitors
- Methotrexate
- Cyclosporine
- Infliximab
- Mycophenolate
โน๏ธ Minor Interactions
- Antacids
- Oral contraceptives
- Cimetidine
- Furosemide
- Indomethacin
๐ฝ๏ธ Food Interactions
Grapefruit may increase levels; avoid.
๐ท Alcohol Interaction
Alcohol may increase hepatotoxicity risk; avoid or limit.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to azathioprine, severe infections, pregnancy (unless essential), lactation, severe bone marrow suppression.
๐ Monitoring Parameters
Complete blood count (CBC), liver function tests (LFTs), renal function, TPMT genotype before therapy.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk; may cause immunosuppression in infant.
๐ Overdose Management
Induce vomiting or gastric lavage; monitor for myelosuppression; supportive care; consider hemodialysis.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for azoprine 50mg tablet
View AllAlternative brands with exact same active ingredient (Azathioprine (50mg)):
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davaindia azathioprine 50mg tabletDavaindia Generic Pharmacy โน30.00 63.4% CHEAPER
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imuzat 50mg tabletElder Pharmaceuticals Ltd โน55.12 32.8% CHEAPER
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azithioprine 50mg tabletAlkem Laboratories Ltd โน58.50 28.7% CHEAPER
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a pin 50mg tabletParry Pharma Pvt Ltd โน60.00 26.8% CHEAPER
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transimune 50mg tabletTroikaa Pharmaceuticals Ltd โน67.26 18% CHEAPER
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azap 50 tabletChandra Bhagat Pharma Pvt Ltd โน75.00 8.5% CHEAPER
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azimune 50mg tabletSun Pharmaceutical Industries Ltd โน79.80 2.7% CHEAPER
-
zesoris-az 50mg tabletTas Med India Pvt Ltd โน80.00 2.4% CHEAPER
-
neoprine 50mg tabletEumedica Pharmaceuticals โน82.50 0.6% COSTLIER
-
autorin 50mg tabletFuture Dermacare Pvt Ltd โน85.00 3.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.