lignocad gel - Lidocaine (2% w/v) medicine

Lox 2% Jelly: Complete Medicine Guide

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🏭 Zydus Cadila 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swallowing
  • Swelling of the face, lips, tongue, or throat
  • Severe dizziness or fainting
  • Irregular heartbeat or palpitations
  • Seizures or convulsions
  • Bluish discolouration of lips or skin
  • Severe skin rash or blistering at the application site

If experiencing severe symptoms, call emergency services immediately.

What is lignocad gel used for?

This medicine is a topical jelly containing lidocaine 2% w/v, used to numb the skin or mucous membranes before minor procedures and to relieve pain, itching, and discomfort from conditions such as haemorrhoids, minor burns, and insect bites. It works by blocking nerve signals in the applied area.

  • Generic Name: Lidocaine (2% w/v)
  • Manufacturer: Zydus Cadila
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 lignocad gel के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल जेली है जिसमें लिडोकेन 2% w/v होता है। इसका उपयोग त्वचा या श्लेष्मा झिल्ली को सुन्न करने के लिए किया जाता है, खासकर छोटी प्रक्रियाओं से पहले, और बवासीर, मामूली जलन, कीड़े के काटने और मुंह के छालों से होने वाले दर्द और खुजली को कम करने के लिए। यह दवा केवल बाहरी उपयोग के लिए है और इसे निगलना नहीं चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर हल्की जलन, चुभन, लालिमा या खुजली शामिल हैं। ये आमतौर पर अस्थायी होते हैं और अपने आप ठीक हो जाते हैं। कभी-कभी चक्कर आना, नींद आना या धुंधली दृष्टि हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई, या अनियमित दिल की धड़कन हो सकती है। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को अपनी एलर्जी और दवाओं के बारे में बताएं। इसे बड़े क्षेत्रों, खुले घावों या जलने पर बिना डॉक्टर की सलाह के न लगाएं। आंखों, कानों और मुंह के संपर्क से बचें। मुंह में लगाने के बाद एक घंटे तक कुछ न खाएं-पिएं। 2 साल से छोटे बच्चों को बिना डॉक्टर की सलाह के न दें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 lignocad gel Uses & Benefits

[{"condition":"Local anaesthesia for minor procedures","description":"This medicine is applied to the skin or mucous membranes to numb the area before minor surgical procedures, such as suturing, incision and drainage, or insertion of a urinary catheter.","evidence":"Well-established"},{"condition":"Symptomatic relief of haemorrhoids","description":"This medicine helps relieve pain, itching, and discomfort associated with haemorrhoids when applied topically to the anal area.","evidence":"Well-established"},{"condition":"Minor burns and insect bites","description":"This medicine provides temporary relief of pain and itching from minor burns, sunburn, and insect bites.","evidence":"Well-established"},{"condition":"Painful oral lesions","description":"This medicine can be applied to mouth ulcers or other painful oral lesions to provide temporary numbing and pain relief.","evidence":"Limited"}]

Off-label uses: [{"condition":"Premature ejaculation","description":"Some clinicians may recommend topical lidocaine to reduce penile sensitivity and prolong intercourse, but this is not an approved indication for this medicine.","evidence":"Limited"},{"condition":"Itching due to eczema or dermatitis","description":"This medicine may be used off-label to relieve itching associated with certain skin conditions, but it should not replace specific treatment for the underlying condition.","evidence":"Limited"}]

Primary treatment for: Local pain and discomfort

Also treats: Haemorrhoids, Minor burns, Insect bites, Oral ulcers

📋 Drug Information

Generic Name(s)Lidocaine (2% w/v)
Brand Namelignocad gel
ManufacturerZydus Cadila
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassLocal anaesthetic (Amides)
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from direct sunlight and moisture. Keep the tube tightly closed when not in use. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine exactly as prescribed by your doctor; do not use more or less than directed.
2
Wash your hands before and after applying this medicine to prevent contamination and accidental exposure.
3
Avoid applying this medicine to large areas of skin or mucous membranes unless specifically instructed.
4
If you are using this medicine for haemorrhoids, apply it after a bowel movement and gently pat the area dry first.
5
Do not use this medicine for more than 7 days without consulting your doctor.
6
If you experience any signs of allergic reaction, stop using this medicine and seek medical help immediately.
7
Keep this medicine away from children and pets.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Local pain
This medicine is commonly used for temporary relief of local pain.
Likely Use
Itching
This medicine can relieve itching associated with minor skin conditions.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Headache
This medicine is not intended for headache relief.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLidocaine is absorbed through intact skin and mucous membranes, but the extent of absorption depends on the surface area, duration of application, and condition of the skin. Systemic absorption is generally low with topical application to intact skin but can be significant when applied to large areas, broken skin, or mucous membranes.
DistributionAfter systemic absorption, lidocaine is distributed widely throughout the body. It crosses the blood-brain barrier and the placenta. The volume of distribution is approximately 1.1 to 2.1 L/kg in adults.
Protein BindingLidocaine is approximately 60% to 80% bound to plasma proteins, primarily alpha-1-acid glycoprotein and albumin.
MetabolismLidocaine is extensively metabolised in the liver by cytochrome P450 enzymes, primarily CYP3A4 and CYP1A2. The main metabolites are monoethylglycinexylidide (MEGX) and glycinexylidide (GX), which have some pharmacological activity.
Half-LifeThe elimination half-life of lidocaine is approximately 1.5 to 2 hours in healthy adults. It may be prolonged in patients with hepatic impairment or reduced hepatic blood flow.
ExcretionLidocaine and its metabolites are excreted primarily in the urine. Less than 10% of the drug is excreted unchanged in the urine.
BioavailabilityThe bioavailability of lidocaine after topical application varies depending on the site and condition of the skin. For this medicine, systemic bioavailability is generally low but can increase with application to mucous membranes or damaged skin.
Onset of ActionThe onset of anaesthetic effect after topical application of this medicine is typically within 2 to 5 minutes, depending on the site of application and the thickness of the skin or mucosa.
Peak Plasma TimePeak plasma concentrations after topical application are usually reached within 1 to 2 hours, but this can vary with the extent of absorption.
Duration of ActionThe anaesthetic effect of this medicine lasts for approximately 30 to 60 minutes after application, although this can vary depending on the individual and the site of application.

How It Works

This medicine works by blocking voltage-gated sodium channels in nerve cell membranes. When applied topically, lidocaine penetrates the skin or mucous membrane and reversibly inhibits the influx of sodium ions into nerve fibres. This action prevents the generation and conduction of nerve impulses, leading to a temporary loss of sensation in the treated area. The effect is localised and reversible, and normal nerve function returns once the medicine is removed or metabolised.

Mechanism Steps

1
Penetration through skin or mucosa: This medicine is applied topically, and lidocaine diffuses through the skin or mucous membrane to reach the underlying nerve fibres.
2
Binding to sodium channels: Lidocaine binds to the intracellular side of voltage-gated sodium channels in the nerve membrane.
3
Blockade of sodium influx: By blocking sodium channels, lidocaine prevents the rapid influx of sodium ions that is necessary for nerve depolarisation.
4
Inhibition of nerve impulse conduction: Without depolarisation, the nerve cannot generate or transmit action potentials, resulting in loss of sensation in the area.
5
Reversible effect: The blockade is reversible, and normal nerve function returns as the medicine is absorbed and metabolised.

💡 How to Take lignocad gel

Strength: Lidocaine 2% w/v topical jelly

1Wash your hands thoroughly before and after applying this medicine.
2Clean and dry the area to be treated.
3Apply a thin layer of the jelly to the affected area using a clean finger or a cotton swab.
4Do not rub the jelly into the skin vigorously; allow it to remain on the surface.
5If applying to the mouth or throat, use a cotton swab and avoid swallowing the jelly.
6Do not cover the area with an airtight dressing unless instructed by a doctor.
7Wash your hands immediately after application to avoid accidental contact with eyes or other mucous membranes.

Dosage Information

Adult DosageThe dosage of this medicine depends on the indication and the area to be treated. For topical anaesthesia of intact skin, apply a thin layer to the affected area as directed by your doctor, usually not more than 3 to 4 times daily. For mucous membranes, use only as instructed by a healthcare professional. The maximum recommended dose for adults is generally not more than 200 mg of lidocaine per application, but this must be individualised by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or frequency.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of lidocaine, especially if they have hepatic or renal impairment. Use with caution and follow the advice of a qualified clinician. Dose adjustment may be necessary based on individual factors.
Renal ImpairmentRenal impairment may prolong the elimination of lidocaine metabolites. However, topical application at recommended doses is unlikely to require dose adjustment. Consult a doctor for guidance if you have severe renal impairment.
Hepatic ImpairmentHepatic impairment can reduce the clearance of lidocaine, increasing the risk of systemic toxicity. Use with caution and under medical supervision. Dose reduction may be necessary in severe hepatic impairment.
Maximum Daily DoseThe maximum daily dose of lidocaine from this medicine depends on the area of application and the concentration. Generally, do not exceed 200 mg of lidocaine per day from topical products without medical supervision. For this 2% w/v jelly, this corresponds to a maximum of 10 grams of jelly per day, but individual limits must be set by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Not applicable
This medicine is for topical use and does not interact with food.
Grapefruit
Not applicable
No known interaction with topical lidocaine.

⏰ What to Do If You Miss a Dose

📌 If you are using this medicine on a scheduled basis and miss a dose
→ Apply the missed dose as soon as you remember.
💡 If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
📌 If you miss more than one dose
→ Do not apply extra medicine to make up for missed doses.
💡 Resume your normal schedule and consult your doctor if you have concerns.

⚠️ Side Effects of lignocad gel

✅ Common Side Effects

Application site burning (Common (1-10%))
This usually resolves on its own. If it persists or worsens, consult your doctor.
Application site stinging (Common (1-10%))
Usually temporary. Avoid applying to broken skin unless directed.
Application site redness (Common (1-10%))
May indicate irritation. Discontinue if severe and consult a doctor.
Itching (Common (1-10%))
If itching is severe or accompanied by rash, stop use and seek medical advice.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling of face, lips, or throat, difficulty breathing, or dizziness.
Systemic toxicity (e.g., seizures, cardiac arrest) (Rare (<0.1%))
This can occur with excessive application or application to large areas. Seek emergency medical help if you experience confusion, seizures, slow heartbeat, or fainting.
Methaemoglobinaemia (Rare (<0.1%))
Symptoms include bluish discolouration of lips and skin, shortness of breath, and fatigue. Seek immediate medical attention.

⚠️ Rare Side Effects

Contact dermatitis
Discontinue use and consult a doctor if you develop a persistent rash at the application site.
Blurred vision
Avoid driving or operating machinery until vision clears. If persistent, consult a doctor.
Drowsiness
Do not drive or operate machinery if you feel drowsy. Consult a doctor if it persists.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Cimetidine Major
Beta-blockers Moderate
Class I antiarrhythmics Major
CYP3A4 inhibitors Moderate

🚨 Major Interactions

  • Class I antiarrhythmics (e.g., tocainide, mexiletine)
  • Cimetidine

⚡ Moderate Interactions

  • Beta-blockers (e.g., propranolol, metoprolol)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

🍷 Alcohol Interaction

Alcohol may increase the central nervous system depressant effects of lidocaine if significant systemic absorption occurs. It is advisable to avoid alcohol while using this medicine, especially on large areas or mucous membranes.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to lidocaine or other amide-type local anaesthetics.","Application to large areas of broken skin or burns without medical supervision.","Use in children under 2 years of age unless prescribed by a doctor.","Avoid use in the presence of severe infection or inflammation at the application site unless directed by a doctor."]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes, ears, and mucous membranes unless specifically instructed.","Do not apply to large areas of skin or for prolonged periods without medical advice.","If used in the mouth or throat, do not eat or drink for at least one hour after application due to risk of choking.","Keep out of reach of children.","Consult a doctor if symptoms persist or worsen.","Do not use if the packaging is damaged or the product has expired."]

🤱 Lactation Safety

Lidocaine is excreted in breast milk in small amounts. Topical application to areas away from the breast is unlikely to affect a nursing infant. However, to minimise infant exposure, avoid applying to the breast area and consult a doctor before use.

💊 Overdose Management

Overdose with this medicine is unlikely when used as directed. However, excessive application or accidental ingestion can lead to systemic toxicity. Symptoms of overdose include dizziness, drowsiness, confusion, seizures, slow heartbeat, and difficulty breathing. If overdose is suspected, remove the product from the skin, wash the area with soap and water, and seek immediate medical attention. Treatment is supportive and may include monitoring of vital signs and administration of anticonvulsants or cardiovascular support as needed.

⏰ Missed Dose

This medicine is usually applied as needed for symptom relief. If you are using it on a scheduled basis and miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra medicine to make up for a missed dose.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you are allergic to lidocaine or any other medicines. Do not apply this medicine to large areas of skin, open wounds, or burns without medical advice. Avoid contact with the eyes, ears, and mouth unless specifically instructed by a healthcare professional. If this medicine is used in the mouth or throat, do not eat or drink for at least one hour after application to avoid choking. Do not use this medicine on children under the age of 2 years unless prescribed by a doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of the reach of children. Do not use this medicine for longer than recommended without consulting your doctor. If your symptoms do not improve or worsen, seek medical advice.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of lidocaine, especially if they have liver or kidney impairment. Use this medicine with caution and follow your doctor's advice. Monitor for signs of dizziness, drowsiness, or confusion.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Topical lidocaine is generally considered safe during pregnancy when used in small amounts, but it is best to minimise exposure and use only when necessary.

🏥 Post-Surgery Considerations

This medicine may be used after surgery to numb the surgical site and relieve pain, but only if recommended by your surgeon. Follow your surgeon's instructions for application and duration.

🦷 Dental Procedures

This medicine can be used in the mouth to numb the gums or oral mucosa before dental procedures, but it should be applied by a dental professional or as directed. Do not swallow the jelly, and avoid eating or drinking for at least one hour after application.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hygiene at the application site to prevent infection.
🥗
Avoid scratching or rubbing the treated area to prevent irritation.
😴
Wear loose-fitting clothing if applying to sensitive areas like haemorrhoids.
💧
Stay hydrated and eat a high-fibre diet to prevent constipation if using for haemorrhoids.
🧘
Follow your doctor's advice for underlying conditions that may be causing pain or discomfort.

🏋️ Exercise Considerations

There are no specific exercise restrictions while using this medicine. However, if you experience dizziness or drowsiness after application, avoid activities that require alertness, such as driving or operating machinery, until you feel normal.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables to support overall health.
If using for haemorrhoids, increase fibre intake to soften stools.
Stay well hydrated to maintain healthy skin and mucous membranes.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to work. However, if you experience drowsiness or dizziness due to systemic absorption, avoid driving or operating heavy machinery until the effects wear off.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any signs of allergic reaction or systemic toxicity. Do not stop prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is generally not recommended without medical supervision. Prolonged application over large areas may increase the risk of systemic absorption and toxicity. If you need to use this medicine for more than 7 days, consult your doctor to determine if continued use is appropriate and to monitor for any adverse effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral pain relievers

For systemic pain relief, oral medications such as paracetamol or ibuprofen may be used, but they do not provide local numbing.

Evidence: Well-established
Cold compress

Applying a cold pack can help reduce pain and swelling for minor injuries or insect bites.

Evidence: Well-established
Sitz baths

Warm sitz baths can help relieve discomfort from haemorrhoids and may complement the use of this medicine.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine as needed.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When travelling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially if travelling internationally. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. Keep it away from direct sunlight and moisture. If you are travelling across time zones, continue using it as needed for symptom relief; no specific time zone adjustment is required for topical use.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with painful haemorrhoids
He was prescribed this medicine to apply after bowel movements. He noticed significant relief in pain and itching within a few days. He learned to apply a thin layer and avoid excessive use.
💡 Lesson: Using this medicine as directed provides effective relief for haemorrhoid symptoms without systemic side effects.
👤 A 60-year-old woman before a minor skin procedure
She was advised to apply this medicine to the area 15 minutes before a small excision. The procedure was painless, and she experienced no side effects. She was reminded not to apply it to large areas.
💡 Lesson: This medicine effectively numbs the skin for minor procedures when applied correctly and in the recommended amount.

💬 Questions Patients Often Ask

Q: How long does this medicine take to work?

A: This medicine usually starts working within 2 to 5 minutes after application, with maximum effect in about 10 to 15 minutes.

Q: Can I use this medicine on my gums?

A: This medicine can be used on mucous membranes such as the gums only if instructed by a healthcare professional. Do not swallow it.

Q: Is this medicine safe for children?

A: This medicine should not be used in children under 2 years of age unless prescribed by a doctor. For older children, consult a pediatrician for appropriate use.

Q: What should I do if I miss a dose?

A: If you are using this medicine on a schedule, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How often can I apply this medicine?
  • Is it safe to use this medicine during pregnancy?
  • Can I use this medicine on broken skin?
  • What should I do if I accidentally swallow this medicine?
  • Does this medicine interact with other topical products?

🔄 Substitutes for lignocad gel

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be swallowed for stomach pain.
    Fact: This medicine is for external use only and must not be swallowed. It is not intended to treat stomach pain.
  • Myth: Applying more jelly will make it work faster.
    Fact: Applying more than the recommended amount does not speed up the effect and can increase the risk of side effects.
  • Myth: This medicine is safe to use on any part of the body.
    Fact: It should not be applied to large areas, broken skin, or mucous membranes without medical advice.

🔄 Alternative Options

Generic Alternatives

  • Lidocaine 2% w/v topical jelly (generic)

Brand Alternatives

  • Lox 2% Jelly

📊 Comparison with Similar Medicines

[{"medicine":"Lidocaine 2% jelly","strength":"2% w/v","form":"Jelly","route":"Topical","onset":"2-5 minutes","duration":"30-60 minutes"},{"medicine":"Lidocaine 5% ointment","strength":"5% w/w","form":"Ointment","route":"Topical","onset":"3-5 minutes","duration":"1-2 hours"},{"medicine":"Lidocaine 2% gel","strength":"2% w/w","form":"Gel","route":"Topical","onset":"2-5 minutes","duration":"30-60 minutes"}]

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