anefol xt injection - Ferrous Ascorbate (NA) + Folic Acid (NA) medicine

Anefol XT Injection - Uses, Price, Side Effects

4.5 (11 reviews)
๐Ÿญ Mac Millon Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is anefol xt injection used for?

Anefol XT Injection is used to treat iron and folate deficiency anemia. It contains Ferrous Ascorbate, which provides iron for hemoglobin production, and Folic Acid, which supports red blood cell formation. It is administered by a healthcare professional and helps improve energy levels and reduce fatigue associated with anemia.

  • Generic Name: Ferrous Ascorbate + Folic Acid
  • Manufacturer: Mac Millon Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š anefol xt injection Uses & Benefits

Iron deficiency anemia, Megaloblastic anemia due to folate deficiency, Anemia of chronic disease, Pregnancy and lactation supplementation

Off-label uses: Restless legs syndrome, Attention deficit hyperactivity disorder (iron deficiency)

๐Ÿ“‹ Drug Information

Generic Name(s)Ferrous Ascorbate + Folic Acid
Brand NameApale Tablet
ManufacturerMac Millon Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassHematinic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionFerrous ascorbate is well absorbed from the gastrointestinal tract; folic acid is absorbed primarily in the proximal small intestine.
DistributionIron is distributed to bone marrow, liver, and spleen; folic acid is distributed to all body tissues.
Protein BindingFerrous ascorbate: >90% bound to transferrin; Folic acid: ~50-60% bound to plasma proteins.
MetabolismFerrous ascorbate: absorbed iron is incorporated into hemoglobin; Folic acid: metabolized in the liver to active forms.
Half-LifeFerrous ascorbate: ~6 hours; Folic acid: ~3-4 hours.
ExcretionIron: primarily excreted in feces; Folic acid: excreted in urine and feces.
BioavailabilityFerrous ascorbate: ~20-30%; Folic acid: ~50-90%.
Onset of ActionFerrous ascorbate: 3-7 days for reticulocyte response; Folic acid: 1-2 days for hematologic response
Peak Plasma TimeFerrous ascorbate: 2-4 hours; Folic acid: 1-2 hours.
Duration of ActionFerrous ascorbate: up to 24 hours; Folic acid: up to 24 hours.

How It Works

Ferrous ascorbate provides iron for hemoglobin synthesis; folic acid is essential for DNA synthesis and red blood cell maturation.

Mechanism Steps

1Ferrous ascorbate dissociates to release ferrous iron and ascorbic acid.
2Ferrous iron is absorbed in the duodenum via DMT1 transporter.
3Ascorbic acid enhances iron absorption by reducing ferric to ferrous iron.

๐Ÿ’ก How to Take anefol xt injection

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of anefol xt injection

โœ… Common Side Effects

  • Nausea
  • Constipation
  • Diarrhea
  • Dark stools
  • Abdominal pain
  • Heartburn

๐Ÿšจ Serious Side Effects

  • Iron overload (hemochromatosis)
  • Allergic reactions
  • Gastrointestinal bleeding
  • Metallic taste

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Antacids Moderate Reduced absorption of ferrous ascorbate
Tetracyclines Moderate Decreased antibiotic efficacy
Levodopa Minor Reduced levodopa absorption

๐Ÿšจ Major Interactions

  • Antacids
  • Tetracyclines
  • Fluoroquinolones
  • Methotrexate
  • Penicillamine

โšก Moderate Interactions

  • Chloramphenicol
  • Proton pump inhibitors
  • H2 receptor antagonists
  • Sulfasalazine

โ„น๏ธ Minor Interactions

  • Vitamin C
  • Calcium supplements
  • Zinc supplements

๐Ÿฝ๏ธ Food Interactions

Dairy products reduce iron absorption, Tea and coffee reduce iron absorption, Vitamin C enhances iron absorption

๐Ÿท Alcohol Interaction

Alcohol may reduce folic acid absorption and increase folate requirements.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hemochromatosis, Iron overload syndromes, Pernicious anemia, Folate-dependent tumors, Hypersensitivity to any component

๐Ÿ“Š Monitoring Parameters

Hemoglobin, Hematocrit, Reticulocyte count, Serum iron, Ferritin, Total iron-binding capacity, Folate levels

๐Ÿคฑ Lactation Safety

Safe; iron and folic acid are excreted in breast milk in small amounts.

๐Ÿ’Š Overdose Management

Gastric lavage, supportive care, deferoxamine for severe iron toxicity.

โฐ Missed Dose

Take as soon as remembered unless almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

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