Ethambutol 800 mg Tablet: Comprehensive Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden vision loss or blurred vision
- Decreased ability to see red and green colors
- Numbness or tingling in hands or feet
- Severe skin rash or blistering
- Yellowing of eyes or skin
- Dark urine or severe abdominal pain
- Difficulty breathing or swelling of face or throat
If experiencing severe symptoms, call emergency services immediately.
What is anacox-e 800mg tablet used for?
Ethambutol 800 mg tablet is an antitubercular medicine used in combination with other drugs to treat tuberculosis. It works by stopping the growth of TB bacteria. It is taken orally, usually once daily, and requires regular eye check-ups.
- Generic Name: Ethambutol
- Manufacturer: Ajanta Pharma Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 anacox-e 800mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एथाम्बुटोल (800 मिलीग्राम) युक्त है और मुख्य रूप से तपेदिक (टीबी) के इलाज के लिए अन्य दवाओं के साथ मिलाकर उपयोग की जाती है। यह टीबी के बैक्टीरिया की कोशिका भित्ति को नष्ट करके उनकी वृद्धि को रोकती है। यह दवा अकेले नहीं ली जानी चाहिए क्योंकि इससे दवा प्रतिरोध हो सकता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, भूख न लगना, सिरदर्द, चक्कर आना और जोड़ों में दर्द शामिल हैं। गंभीर दुष्प्रभावों में दृष्टि में बदलाव (धुंधला दिखना, रंगों में फर्क), हाथ-पैरों में झुनझुनी, एलर्जी, और लिवर की समस्या शामिल हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। बीच में न छोड़ें। खाने के साथ या बिना खाने के ले सकते हैं, लेकिन पेट खराब हो तो खाने के साथ लें। शराब न पिएं। गुर्दे या आंखों की बीमारी हो तो डॉक्टर को बताएं। नियमित आंखों की जांच कराएं।
💊 anacox-e 800mg tablet Uses & Benefits
[{"condition":"Tuberculosis (TB)","description":"Used in combination with other antitubercular drugs for the treatment of active pulmonary and extrapulmonary tuberculosis.","evidence":"Well-established"},{"condition":"Mycobacterium avium complex (MAC) infection","description":"Sometimes used as part of a combination regimen for MAC infections in immunocompromised patients.","evidence":"Established in specific settings"}]
Off-label uses: [{"condition":"Atypical mycobacterial infections","description":"May be used off-label for other nontuberculous mycobacterial infections under specialist guidance.","evidence":"Limited"}]
Primary treatment for: Tuberculosis
Also treats: Mycobacterium avium complex infection
📋 Drug Information
| Generic Name(s) | Ethambutol |
| Brand Name | Actol 800mg Tablet |
| Manufacturer | Ajanta Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Mycobacterial cell wall inhibitors-Ethambutol |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Ethambutol is included in WHO guidelines for the treatment of drug-susceptible tuberculosis as part of combination therapy. |
| ICMR Guideline | ICMR guidelines recommend ethambutol as part of the intensive phase of antitubercular therapy for drug-susceptible TB. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Ethambutol inhibits the enzyme arabinosyl transferase, which is involved in the polymerization of arabinogalactan, a key component of the mycobacterial cell wall. This disruption weakens the cell wall, making the bacteria more susceptible to other drugs and leading to cell death. It is bacteriostatic at usual doses but can be bactericidal at higher concentrations.
Mechanism Steps
💡 How to Take anacox-e 800mg tablet
Strength: Ethambutol 800 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of Ethambutol for tuberculosis is 15-25 mg/kg body weight once daily, depending on the treatment regimen and patient factors. For the 800 mg tablet, the dose may be adjusted based on body weight. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function; dose adjustment may be necessary. Monitor renal function and vision closely. |
| Renal Impairment | Dose reduction is required in patients with renal impairment. The dose should be adjusted based on creatinine clearance. Consult a clinician for individualized dosing. |
| Hepatic Impairment | No specific dose adjustment is recommended for hepatic impairment, but monitor liver function if used with other hepatotoxic drugs. |
| Maximum Daily Dose | The maximum recommended daily dose is 25 mg/kg, but should not exceed 2.5 g per day. Individualized by clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of anacox-e 800mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aluminum hydroxide | Major | |
| Isoniazid | Moderate | |
| Rifampicin | Moderate | |
| Ethionamide | Minor |
🚨 Major Interactions
- Aluminum hydroxide (antacids)
⚡ Moderate Interactions
- Isoniazid
- Rifampicin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine as it may increase the risk of liver toxicity and worsen side effects such as dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ethambutol","Pre-existing optic neuritis","Inability to report visual symptoms (e.g., young children, unconscious patients)","Severe renal impairment without dose adjustment"]
⚠️ Warnings & Precautions
["Optic neuritis: May cause vision changes; baseline and periodic eye exams are recommended.","Renal impairment: Dose reduction needed; monitor renal function.","Peripheral neuropathy: Report numbness or tingling.","Hepatotoxicity: Rare but possible; monitor liver enzymes if combined with other hepatotoxic drugs.","Use in children: Not recommended for young children who cannot report visual symptoms.","Pregnancy: Use only if clearly needed; consult doctor.","Breastfeeding: Excreted in breast milk; consult doctor."]
🤱 Lactation Safety
Ethambutol is excreted in breast milk in small amounts. It is considered safe during breastfeeding, but consult your doctor.
💊 Overdose Management
Overdose may cause nausea, vomiting, dizziness, and visual disturbances. Seek immediate medical attention. Treatment is supportive and symptomatic. Gastric lavage may be considered if ingestion is recent. Hemodialysis may be beneficial in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, as this can lead to treatment failure and drug resistance. Take the tablet with or without food, but if it causes stomach upset, take it with a meal. Avoid alcohol while on this medicine to reduce the risk of liver problems. Inform your doctor if you have kidney disease, eye problems, or diabetes, as dose adjustments may be needed. Regular eye check-ups and kidney function tests are important. Use effective contraception during treatment if you are of childbearing age. Do not share this medicine with others. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced renal function and are at higher risk of side effects. Dose adjustment may be needed. Regular monitoring of vision and kidney function is important.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor. Ethambutol is considered safe in pregnancy when prescribed for TB. Use effective contraception if you are taking other drugs that may harm the fetus.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking Ethambutol. It is generally safe to continue during surgery, but your doctor will advise.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. No specific precautions are usually needed, but maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but if you experience dizziness or fatigue, avoid strenuous activities. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities, but listen to your body and rest when needed.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping early can lead to treatment failure and drug resistance. If you experience serious side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use of Ethambutol is generally well-tolerated when monitored appropriately. The main concern is optic neuritis, which is dose- and duration-dependent. Regular eye exams are recommended. Renal function should be monitored, especially in patients with kidney disease. Peripheral neuropathy may occur with prolonged use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A strategy where a healthcare worker observes the patient taking each dose to ensure adherence.
Evidence: Well-establishedAdequate nutrition helps improve treatment outcomes in TB.
Evidence: Established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
BCG vaccination is recommended for prevention of severe forms of TB in children. Ethambutol treatment does not interfere with vaccines, but consult your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from direct sunlight. If traveling across time zones, consult your doctor about adjusting the timing of doses. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: It may take several weeks to see improvement in TB symptoms. Complete the full course as prescribed.
A: No, you must complete the full course to prevent relapse and drug resistance.
A: Contact your doctor immediately. Vision changes may indicate optic neuritis, which requires prompt evaluation.
🤔 Common Patient Concerns
🔄 Substitutes for anacox-e 800mg tablet
View AllAlternative brands with exact same active ingredient:
-
colubutol 800mg tabletInd Swift Laboratories Ltd ₹23.81 17.9% CHEAPER
-
Tibitol 800mg TabletPCI Pharmaceuticals ₹27.38 5.6% CHEAPER
-
cibutol 800mg tabletMediwin Pharmaceuticals ₹29.00 SAME PRICE
-
ulticox 800mg tabletConcept Pharmaceuticals Ltd ₹29.76 2.6% COSTLIER
-
antol 800mg tabletAan Pharma Pvt Ltd ₹31.00 6.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Ethambutol can be taken alone for TB.
Fact: Ethambutol must always be used in combination with other antitubercular drugs to prevent resistance. - Myth: Ethambutol causes blindness in everyone.
Fact: Optic neuritis is a rare side effect; regular monitoring helps detect it early. - Myth: You can stop ethambutol once you feel better.
Fact: You must complete the full course as prescribed to cure TB and prevent resistance.
🔄 Alternative Options
Generic Alternatives
- Ethambutol 800 mg tablet (generic)
Brand Alternatives
- Combutol 800 Tablet