Ethambutol 800 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blurred vision or decreased colour vision
- Loss of vision or eye pain
- Numbness or tingling in hands or feet
- Yellowing of skin or eyes (jaundice)
- Dark urine or pale stools
- Severe abdominal pain
- Swelling of face, lips, or throat
- Difficulty breathing
- Unusual bleeding or bruising
- Fever with sore throat or mouth ulcers
If experiencing severe symptoms, call emergency services immediately.
What is antol 800mg tablet used for?
This medicine contains Ethambutol 800 mg, an antitubercular drug used to treat tuberculosis. It works by stopping the growth of TB bacteria. It is always used in combination with other TB medicines. The most important side effect is eye problems, so regular eye check-ups are essential.
- Generic Name: Ethambutol (800mg)
- Manufacturer: Aan Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 antol 800mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एथाम्बुटोल 800 मिलीग्राम की एक गोली है, जिसका उपयोग तपेदिक (टीबी) के इलाज के लिए किया जाता है। यह टीबी के बैक्टीरिया की कोशिका भित्ति को नष्ट करके उनकी वृद्धि को रोकती है। यह दवा हमेशा अन्य टीबी की दवाओं जैसे आइसोनियाजिड, रिफैम्पिसिन और पायराजिनामाइड के साथ मिलकर दी जाती है। अकेले इस दवा का उपयोग नहीं किया जाना चाहिए क्योंकि इससे बैक्टीरिया में प्रतिरोधक क्षमता विकसित हो सकती है। यह दवा निमोनिया, सर्दी-जुकाम या अन्य सामान्य संक्रमणों के लिए नहीं है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, भूख न लगना, सिरदर्द, चक्कर आना और जोड़ों में दर्द शामिल हैं। सबसे महत्वपूर्ण दुष्प्रभाव आंखों से जुड़ा है - इस दवा से धुंधली दृष्टि, रंगों में अंतर करने में कठिनाई (विशेषकर लाल और हरे रंग में), या दृष्टि की तीक्ष्णता में कमी हो सकती है। ये आंखों के प्रभाव आमतौर पर दवा बंद करने पर ठीक हो जाते हैं, लेकिन अगर इलाज जारी रहे तो स्थायी नुकसान हो सकता है। अन्य गंभीर दुष्प्रभावों में हाथ-पैरों में सुन्नपन या झुनझुनी, गंभीर एलर्जी प्रतिक्रिया, और लीवर की समस्या (पीलिया, गहरे रंग का पेशाब) शामिल हैं। आंखों में कोई भी बदलाव तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: इस दवा को शुरू करने से पहले अपने डॉक्टर को आंखों की समस्या, गुर्दे की बीमारी, लीवर की बीमारी, मधुमेह, या शराब की लत के बारे में बताएं। इलाज से पहले और इलाज के दौरान नियमित रूप से आंखों की जांच करवानी चाहिए। अगर आपको चक्कर आते हैं या धुंधला दिखता है तो वाहन चलाने या मशीन चलाने से बचें। इस दवा के साथ शराब का सेवन पूरी तरह बंद कर दें क्योंकि इससे लीवर और नसों को नुकसान का खतरा बढ़ जाता है। पेट की परेशानी कम करने के लिए इस दवा को भोजन के साथ लें। बेहतर महसूस होने पर भी डॉक्टर की सलाह के बिना दवा बंद न करें। नियमित जांच और आंखों की जांच के लिए अपॉइंटमेंट लेते रहें।
💊 antol 800mg tablet Uses & Benefits
[{"condition":"Pulmonary tuberculosis","description":"Used as part of a multi-drug regimen to treat active tuberculosis infection of the lungs.","evidence":"Well-established"},{"condition":"Extrapulmonary tuberculosis","description":"Used in combination therapy for TB affecting lymph nodes, bones, joints, urinary tract, or other organs.","evidence":"Well-established"},{"condition":"Tuberculous meningitis","description":"Included in treatment regimens for TB infection of the membranes covering the brain and spinal cord.","evidence":"Well-established"},{"condition":"Mycobacterium avium complex (MAC) infection","description":"Sometimes used in combination with other drugs for MAC infections, especially in immunocompromised patients.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Atypical mycobacterial infections","description":"Occasionally used for infections caused by other non-tuberculous mycobacteria under specialist guidance.","evidence":"Limited"}]
Primary treatment for: Tuberculosis
Also treats: Mycobacterium avium complex infection, Atypical mycobacterial infections
📋 Drug Information
| Generic Name(s) | Ethambutol (800mg) |
| Brand Name | antol 800mg tablet |
| Manufacturer | Aan Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Mycobacterial cell wall inhibitors-Ethambutol |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container, tightly closed. Do not refrigerate unless specified by the manufacturer. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | The World Health Organization recommends ethambutol as part of first-line treatment for drug-susceptible tuberculosis in combination with isoniazid, rifampicin, and pyrazinamide. It is also used in certain drug-resistant TB regimens. Always follow national TB program guidelines. |
| ICMR Guideline | The Indian Council of Medical Research and the Revised National Tuberculosis Control Program (RNTCP) recommend ethambutol as a first-line antitubercular drug in combination therapy for tuberculosis. Doses are weight-based and must be adjusted in renal impairment. Regular monitoring for optic neuritis is advised. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the synthesis of arabinogalactan, a key component of the mycobacterial cell wall. Specifically, it interferes with the enzyme arabinosyl transferase, which is responsible for polymerizing arabinose into the cell wall. Without a proper cell wall, the bacteria cannot grow and multiply, and they become more susceptible to the body's immune defenses and other antitubercular drugs. This medicine is bacteriostatic at usual doses, meaning it stops bacterial growth rather than directly killing the bacteria. However, when combined with other drugs like isoniazid and rifampicin, it helps achieve a bactericidal effect and prevents the emergence of resistant strains.
Mechanism Steps
💡 How to Take antol 800mg tablet
Strength: Ethambutol 800 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 15 to 25 mg per kg of body weight, taken once daily. For a 800 mg tablet, this typically corresponds to one tablet daily for patients weighing around 40 to 50 kg, but the exact dose depends on the patient's weight, kidney function, and the specific treatment regimen. This medicine is always used in combination with other antitubercular drugs. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 13 years of age unless specifically prescribed by a specialist. |
| Elderly Dosage | Elderly patients may have reduced kidney function and are at higher risk of side effects, especially optic neuritis. Dose should be adjusted based on renal function. Regular eye examinations are essential. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine should be reduced. For creatinine clearance 10-50 mL/min, the usual dose is 15-25 mg/kg every 24-36 hours. For creatinine clearance less than 10 mL/min, the dose is 15-25 mg/kg every 48 hours. Dose must be individualized by a qualified clinician based on renal function and monitoring. |
| Hepatic Impairment | No specific dosage adjustment is established for hepatic impairment, but this medicine is partially metabolized in the liver. Use with caution in patients with severe liver disease. Monitor liver function tests regularly. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 25 mg per kg of body weight, not to exceed 2.5 grams per day. Doses above this increase the risk of optic neuritis. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of antol 800mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aluminium hydroxide | Major | |
| Isoniazid | Major | |
| Rifampicin | Moderate | |
| Aminoglycosides | Moderate | |
| Ethionamide | Moderate | |
| Disulfiram | Minor | |
| Warfarin | Minor | |
| Phenytoin | Minor | |
| Carbamazepine | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Aluminium hydroxide (antacids)
- Other antitubercular drugs (isoniazid, rifampicin, pyrazinamide)
⚡ Moderate Interactions
- Aminoglycosides (e.g., gentamicin, amikacin)
- Ethionamide
🍷 Alcohol Interaction
Avoid alcohol completely while taking this medicine. Alcohol increases the risk of liver damage and can worsen nerve-related side effects such as peripheral neuropathy. It may also reduce the effectiveness of tuberculosis treatment and increase the risk of treatment failure.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to ethambutol","Active optic neuritis (inflammation of the eye nerve)","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["This medicine can cause optic neuritis, which may lead to permanent vision loss if not detected early. Baseline and regular eye exams are mandatory.","Use with caution in patients with renal impairment. Dose adjustment is required.","Use with caution in patients with liver disease. Monitor liver function.","Avoid alcohol during treatment to reduce risk of liver and nerve toxicity.","This medicine should never be used alone for tuberculosis; it must be part of a combination regimen.","Patients with diabetes may experience difficulty in recognizing symptoms of hypoglycemia due to blurred vision.","Elderly patients are at higher risk of optic neuritis and should be monitored closely.","This medicine may impair your ability to drive or operate machinery if you experience dizziness or vision changes.","Do not share this medicine with anyone else, even if they have similar symptoms.","Complete the full course of treatment as prescribed, even if you feel better."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. The amount is generally considered small, but because of potential serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe optic neuritis, nausea, vomiting, dizziness, and hallucinations. There is no specific antidote. Treatment is supportive and symptomatic. Immediate medical attention is required. If overdose is suspected, contact a poison control center or emergency room immediately. Gastric lavage may be considered if ingestion is recent. Hemodialysis may be beneficial in severe cases, especially in patients with renal failure.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Before starting this medicine, tell your doctor if you have any eye problems, kidney disease, liver disease, diabetes, or alcohol use disorder. You must have a baseline eye examination before treatment and regular eye check-ups during treatment, especially if you are on higher doses or long-term therapy. Do not drive or operate heavy machinery if you experience dizziness or blurred vision. Avoid alcohol completely while taking this medicine because it increases the risk of liver damage and nerve problems. Take this medicine with food to reduce stomach upset. Do not stop taking this medicine without your doctor's advice, even if you feel better, because stopping early can cause the infection to return and become resistant. Keep all follow-up appointments for blood tests and eye exams. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. This medicine passes into breast milk, so breastfeeding should be discussed with your doctor. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of optic neuritis and peripheral neuropathy. Kidney function declines with age, so dose adjustment may be necessary. Regular eye exams and monitoring of kidney function are essential. Falls risk may increase if dizziness or vision problems occur.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before starting or continuing this medicine. Tuberculosis treatment is essential during pregnancy, but the regimen may need to be adjusted. This medicine crosses the placenta, and its safety in pregnancy is not fully established. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
If you are undergoing surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medications used during surgery. Your doctor may advise temporary discontinuation or adjustment. Do not stop the medicine without medical advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There are no specific contraindications, but your dentist may take precautions if you have bleeding problems or are on other medications. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine, but avoid strenuous activities if you feel dizzy or have vision changes. Consult your doctor before starting any new exercise program. If you experience numbness or tingling in your feet, avoid activities that require good balance.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or vision changes, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how this medicine affects you. If your job requires good vision, inform your employer and take necessary precautions. Most people can continue their normal work activities with some adjustments.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as vision changes, severe allergic reactions, or liver problems, contact your doctor immediately. Your doctor may stop the medicine or adjust the dose. Stopping treatment early can lead to treatment failure and drug resistance.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of optic neuritis, which may become permanent if not detected early. Peripheral neuropathy may also develop with prolonged use. Regular monitoring of vision, liver function, and kidney function is required. The duration of treatment is usually 6 months or longer for tuberculosis, but must be determined by your doctor. Do not use for longer than prescribed without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
If this medicine is not suitable due to side effects, your doctor may switch to alternative drugs like streptomycin or fluoroquinolones.
Evidence: Well-establishedA healthy diet and vitamin supplementation can help manage side effects and support recovery.
Evidence: Supportive💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, live vaccines should be avoided in immunocompromised patients. Consult your doctor before receiving any vaccinations while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, consult your doctor about adjusting the timing of your doses. Carry enough supply for the entire trip. Check customs regulations for carrying prescription medicines. Do not miss any doses while traveling.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within hours, but you may not notice symptom improvement for a few weeks. It is important to complete the full course as prescribed.
A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Yes, this medicine can cause vision problems such as blurred vision or decreased colour vision. Regular eye exams are essential. Report any vision changes immediately.
A: No, you must complete the full course as prescribed by your doctor, even if you feel better. Stopping early can lead to treatment failure and resistance.
🤔 Common Patient Concerns
🔄 Substitutes for antol 800mg tablet
View AllAlternative brands with exact same active ingredient:
-
colubutol 800mg tabletInd Swift Laboratories Ltd ₹23.81 23.2% CHEAPER
-
Tibitol 800mg TabletPCI Pharmaceuticals ₹27.38 11.7% CHEAPER
-
anacox-e 800mg tabletAjanta Pharma Ltd ₹29.00 6.5% CHEAPER
-
cibutol 800mg tabletMediwin Pharmaceuticals ₹29.00 6.5% CHEAPER
-
ulticox 800mg tabletConcept Pharmaceuticals Ltd ₹29.76 4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Ethambutol can be taken alone to treat tuberculosis.
Fact: Ethambutol must always be used in combination with other antitubercular drugs to prevent resistance. - Myth: You can stop taking ethambutol once you feel better.
Fact: You must complete the full course as prescribed, even if symptoms improve, to prevent relapse and resistance. - Myth: Ethambutol is safe for everyone.
Fact: Ethambutol is not safe for people with optic neuritis or severe kidney disease, and requires monitoring in others. - Myth: Ethambutol causes permanent vision loss in everyone.
Fact: Vision problems are uncommon and usually reversible if detected early. Regular eye exams help prevent permanent damage.
🔄 Alternative Options
Generic Alternatives
- Ethambutol 800 mg tablet (various manufacturers)
Brand Alternatives
- Mycobutol 800 tablet