amlosafe-at 2.5mg/25mg tablet - Uses, Price, Side Effects & Substitutes
What is amlosafe-at 2.5mg/25mg tablet used for?
Amlokind-AT Tablet (Amlodipine + Atenolol) is used to treat Hypertension. It contains Amlodipine (2.5mg) + Atenolol (25mg), which Amlodipine inhibits calcium influx across cell membranes in vascular smooth musc. Always consult your doctor before use. Take as prescribed.
- Generic Name: Amlodipine + Atenolol
- Manufacturer: Aristo Pharmaceuticals Pvt Ltd
- Medicine Form: Allopathy
- Pregnancy Category: C
🇮🇳 amlosafe-at 2.5mg/25mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
amlosafe-at 2.5mg/25mg tablet का उपयोग मुख्य रूप से cardiac और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Amlodipine (2.5mg) + Atenolol (25mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Amlodipine + Atenolol |
|---|---|
| Brand Name | Amlokind-AT Tablet |
| Manufacturer | Aristo Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blocker + Beta blocker |
| Route of Administration | Oral |
| Storage | Store at 20-25°C (68-77°F), protect from light and moisture |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take amlosafe-at 2.5mg/25mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 20-25°C (68-77°F), protect from light and moisture
⚙️ How amlosafe-at 2.5mg/25mg tablet Works
Amlodipine inhibits calcium influx across cell membranes in vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced peripheral resistance. Atenolol selectively blocks beta-1 adrenergic receptors, decreasing heart rate, contractility, and cardiac output.
💊 amlosafe-at 2.5mg/25mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Hypertension, angina pectoris (chronic stable angina, vasospastic angina)
⚠️ What are the side effects of amlosafe-at 2.5mg/25mg tablet?
✅ Common Side Effects
- Edema (ankle/foot)
- Headache
- Dizziness
- Fatigue
- Nausea
- Flushing
- Palpitations
- Bradycardia
- Cold extremities
🚨 Serious Side Effects
- Severe hypotension
- Heart failure exacerbation
- Bradyarrhythmias
- Bronchospasm
- Hepatotoxicity (rare)
- Stevens-Johnson syndrome (rare)
⚠️ Rare Side Effects
- Gingival hyperplasia
- Leukopenia
- Thrombocytopenia
- Vasculitis
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
🔄 Best Substitutes for amlosafe-at 2.5mg/25mg tablet
View AllAlternative medicines with exact same composition and strength (Amlodipine (2.5mg) + Atenolol (25mg)):
- amlonova 2.5mg/25mg tabletTTK Healthcare Ltd₹25.00💰 59.9% CHEAPER
- nutin sa 2.5 mg/25 mg tabletEmcure Pharmaceuticals Ltd₹51.45💰 17.5% CHEAPER
- atpure-sa 2.5mg/25mg tabletNucron Pharmaceuticals Pvt Ltd₹60.90💰 2.4% CHEAPER
- tenolol-am 25 tabletIpca Laboratories Ltd₹61.40💰 1.6% CHEAPER
- amlosafe-at 2.5mg/25mg tabletAristo Pharmaceuticals Pvt Ltd₹62.40💰 Same price
Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | Increased risk of bradycardia, heart block, and hypotension |
| Clonidine | Major | Rebound hypertension upon clonidine withdrawal |
| NSAIDs | Moderate | Reduced antihypertensive effect |
| Grapefruit juice | Minor | Increased amlodipine levels |
🚨 Major Interactions
- Beta blockers (other)
- Calcium channel blockers (verapamil, diltiazem)
- CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir)
- Clonidine
- Digitalis glycosides
⚡ Moderate Interactions
- NSAIDs
- Antihypertensives (additive effect)
- Insulin
- Oral hypoglycemics
- Anesthetics
ℹ️ Minor Interactions
- Cimetidine
- Grapefruit juice (amlodipine)
- Antacids
🍽️ Food Interactions
Grapefruit juice may increase amlodipine levels; avoid excessive intake. Food does not significantly affect atenolol absorption.
🍷 Alcohol Interaction
Alcohol may enhance hypotensive effect; avoid excessive alcohol consumption.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to components, cardiogenic shock, severe bradycardia, heart block (2nd/3rd degree), sick sinus syndrome, severe hypotension, acute heart failure, asthma/COPD (atenolol), peripheral vascular disease (severe)
📊 Monitoring Parameters
Blood pressure, heart rate, ECG, serum electrolytes, renal function, hepatic function, blood glucose (in diabetics)
🤱 Lactation Safety
Low risk; both drugs excreted in breast milk in small amounts. Caution advised.
💊 Overdose Management
Supportive care; atropine for bradycardia, vasopressors for hypotension, calcium gluconate for calcium channel blocker overdose, glucagon for beta blocker overdose
⏰ Missed Dose
Take as soon as remembered if within 12 hours; skip if close to next dose. Do not double dose.
🛑 Myths vs. Facts about amlosafe-at 2.5mg/25mg tablet
- Myth: Generic substitutes of amlosafe-at 2.5mg/25mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Amlodipine (2.5mg) + Atenolol (25mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of amlosafe-at 2.5mg/25mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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