ambrodil-s syrup - Ambroxol (15mg/5ml) + Salbutamol (1mg/5ml) medicine

Ambrodil-S Syrup: Complete Medicine Guide

No reviews yet
🏭 Aristo Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for combination in productive cough; individual components well-established.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or worsening of breathing
  • Chest pain or irregular heartbeat
  • Severe dizziness or fainting
  • Swelling of face, lips, or throat
  • Severe skin rash or itching
  • Blood in cough or vomit
  • Muscle weakness or cramps

If experiencing severe symptoms, call emergency services immediately.

What is ambrodil-s syrup used for?

This medicine is a combination of ambroxol and salbutamol used to treat productive cough with bronchospasm. It works by thinning mucus and opening airways. It is available as a syrup and is taken orally, usually three times a day. It should be used only under medical supervision.

  • Generic Name: Ambroxol + Salbutamol
  • Manufacturer: Aristo Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ambrodil-s syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एम्ब्रोक्सोल और साल्बुटामोल का संयोजन है, जिसका उपयोग बलगम वाली खांसी और सांस की नली में सिकुड़न के इलाज के लिए किया जाता है। यह बलगम को पतला करके बाहर निकालने में मदद करती है और सांस की नली को खोलती है, जिससे सांस लेने में आसानी होती है। यह दवा ब्रोंकाइटिस, अस्थमा और सीओपीडी जैसी स्थितियों में उपयोगी है। इसका सेवन डॉक्टर के परामर्श से ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, सिरदर्द, चक्कर आना, हाथ-पैर कांपना और धड़कन तेज होना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, तेज धड़कन या छाती में दर्द हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को कम या ज्यादा न करें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही माप के लिए मापने वाला कप या चम्मच इस्तेमाल करें। यदि आपको चक्कर या कंपन महसूस हो तो वाहन चलाने या मशीन चलाने से बचें। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह या थायरॉइड की समस्या है तो डॉक्टर को बताएं। 7 दिनों से अधिक खांसी रहने पर डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 ambrodil-s syrup Uses & Benefits

[{"condition":"Productive cough with thick mucus","description":"Helps loosen and clear mucus from the airways, making cough more productive.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Relieves cough and improves airway clearance in acute bronchitis.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Used as an adjunct to relieve bronchospasm and facilitate mucus clearance.","evidence":"Moderate"},{"condition":"Asthma with mucus plugging","description":"May help in combination with other asthma medications to relieve bronchospasm and thin mucus.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of bronchopulmonary dysplasia in preterm infants","description":"Ambroxol has been studied off-label for this purpose, but evidence is not conclusive.","evidence":"Limited"}]

Primary treatment for: Productive cough with bronchospasm

Also treats: Acute bronchitis, Chronic obstructive pulmonary disease (COPD), Asthma

📋 Drug Information

Generic Name(s)Ambroxol + Salbutamol
Brand NameAmbrodil-S Syrup
ManufacturerAristo Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Beta-2 Adrenergic Agonist
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not refrigerate. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine only for productive cough with bronchospasm; avoid in dry cough.
2
Assess cardiovascular status before prescribing, especially in elderly and those with heart disease.
3
Monitor serum potassium levels if used with diuretics or corticosteroids.
4
Advise patients to avoid driving or operating machinery until they know how the medicine affects them.
5
Instruct patients not to exceed the recommended dose and to complete the prescribed course.
6
Caution patients about the risk of tremors and palpitations, and advise them to report if severe.
7
For children, calculate dose based on weight and age, and use a calibrated measuring device.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
Dry cough
This medicine is not effective for dry cough.
Not Primary
Wheezing and breathlessness
Salbutamol component helps relieve bronchospasm.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSalbutamol is rapidly absorbed from the gastrointestinal tract after oral administration. Ambroxol is also well absorbed orally. However, oral salbutamol undergoes extensive first-pass metabolism, reducing its systemic bioavailability.
DistributionSalbutamol is widely distributed in body tissues, including the lungs. Ambroxol distributes into lung tissue, bronchial secretions, and plasma. Both agents cross the placenta and are excreted in breast milk.
Protein BindingSalbutamol is approximately 10% bound to plasma proteins. Ambroxol is about 80-90% bound to plasma proteins.
MetabolismSalbutamol is metabolized in the liver primarily by conjugation to inactive sulfate esters. Ambroxol is metabolized in the liver by glucuronidation and some oxidation.
Half-LifeThe elimination half-life of salbutamol is approximately 4-6 hours. The elimination half-life of ambroxol is approximately 7-12 hours.
ExcretionSalbutamol and its metabolites are excreted mainly in the urine, with a small amount in feces. Ambroxol is excreted primarily in the urine as metabolites.
BioavailabilityOral salbutamol has a bioavailability of approximately 30% due to first-pass metabolism. Oral ambroxol bioavailability is about 70-80%.
Onset of ActionBronchodilation from salbutamol occurs within 15-30 minutes after oral administration. Ambroxol's mucolytic effect begins within 30-60 minutes.
Peak Plasma TimePeak plasma concentrations of salbutamol are reached in about 2-4 hours. Ambroxol peaks in about 1-3 hours.
Duration of ActionBronchodilation from oral salbutamol lasts about 4-6 hours. Ambroxol's mucolytic effect lasts about 6-8 hours.

How It Works

This medicine combines two active ingredients with complementary actions. Ambroxol is a mucolytic agent that reduces mucus viscosity by breaking down acidic mucopolysaccharide fibers and stimulating surfactant production, thereby facilitating mucus clearance. Salbutamol is a short-acting beta-2 adrenergic agonist that relaxes bronchial smooth muscle by stimulating beta-2 receptors, leading to bronchodilation and improved airflow. Together, they help relieve cough and improve breathing in conditions with excessive mucus and bronchospasm.

Mechanism Steps

1
Salbutamol binds beta-2 receptors: Salbutamol selectively binds to beta-2 adrenergic receptors on bronchial smooth muscle cells.
2
Activation of adenylate cyclase: This binding activates adenylate cyclase, increasing cyclic AMP levels inside the cells.
3
Bronchial smooth muscle relaxation: Increased cyclic AMP leads to relaxation of bronchial smooth muscle, resulting in bronchodilation.
4
Ambroxol reduces mucus viscosity: Ambroxol breaks down acidic mucopolysaccharide fibers in mucus, making it thinner and less sticky.
5
Enhanced mucociliary clearance: Thinner mucus is more easily moved by cilia and coughed out, improving airway clearance.

💡 How to Take ambrodil-s syrup

Strength: Each 5 ml contains Ambroxol 15 mg and Salbutamol 1 mg.

1Shake the bottle well before each use.
2Use the measuring cup or spoon provided to measure the correct dose.
3Take the medicine orally with or without food.
4Swallow the syrup directly; do not mix with other liquids unless advised.
5Rinse the measuring cup after each use.
6Close the bottle tightly after use.
7Wash your hands after handling the medicine.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 10 ml (two teaspoons) three times a day, or as prescribed by your doctor. The dose may be adjusted based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the cardiovascular effects of salbutamol. Use with caution and lower doses may be considered. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with severe renal impairment. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with severe hepatic impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 30 ml (6 teaspoons) in divided doses, or as prescribed by a doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase nervousness and palpitations.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ambrodil-s syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce stomach upset. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if severe.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Tremor (Common (5-10%))
Usually mild and temporary. Report to doctor if bothersome.
Palpitations (Common (5-10%))
Report to doctor if persistent or accompanied by chest pain.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Seek immediate medical attention if you feel palpitations, chest pain, or fainting.
Severe hypokalemia (Rare (<0.1%))
Consult doctor if you experience muscle weakness, cramps, or fatigue.

⚠️ Rare Side Effects

Bronchospasm paradoxical
Stop medicine and seek immediate medical help if breathing worsens.
Liver enzyme elevation
Report to doctor if you notice yellowing of eyes or skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Furosemide Moderate
Digoxin Moderate
Corticosteroids Moderate
Amoxicillin Minor

🚨 Major Interactions

  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide, thiazides)
  • Digoxin
  • Corticosteroids

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and cardiovascular side effects such as palpitations. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ambroxol, salbutamol, or any component of the formulation","Severe cardiovascular disease including severe heart failure, uncontrolled hypertension, and severe coronary artery disease","Thyrotoxicosis","Severe hepatic or renal impairment (relative contraindication)","Children under 2 years of age"]

⚠️ Warnings & Precautions

["Do not use for dry cough or cough lasting more than 7 days without medical advice.","Use with caution in patients with heart disease, hypertension, diabetes, hyperthyroidism, or seizure disorders.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not exceed the recommended dose; excessive use may cause tremors, palpitations, and hypokalemia.","Consult a doctor before use if pregnant, planning pregnancy, or breastfeeding.","Keep out of reach of children.","Do not use if the bottle is damaged or the syrup appears discolored."]

🤱 Lactation Safety

Salbutamol and ambroxol are excreted in breast milk. Caution is advised. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe tachycardia, tremor, palpitations, hypokalemia, and hyperglycemia. Seek immediate medical attention. Treatment is supportive and symptomatic. Monitor cardiac function and serum potassium levels. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Shake the bottle well before each use. Use a proper measuring cup or spoon to ensure accurate dosing. Avoid driving or operating heavy machinery if you feel dizzy or shaky after taking this medicine. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or liver or kidney disease. Do not use this medicine for a dry cough or for cough lasting more than 7 days without consulting a doctor. Keep out of reach of children. Store at room temperature, away from direct sunlight and moisture. Do not use after the expiry date.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular effects of salbutamol, such as tachycardia and palpitations. Use with caution and lower doses may be considered. Monitor heart rate and blood pressure regularly.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. The safety of this combination during pregnancy is not well established. Your doctor will assess the potential benefits and risks.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, especially if you have heart or lung conditions. It may interact with other medications used during surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth or interact with local anesthetics. No specific precautions are usually needed, but medical advice is recommended.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Avoid smoking and exposure to secondhand smoke.
😴
Use a humidifier to keep airways moist.
💧
Practice deep breathing exercises to improve lung function.
🧘
Get adequate rest to support recovery.
🌞
Avoid allergens and pollutants that trigger cough.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience dizziness, palpitations, or tremors after taking this medicine. Light activities like walking may be beneficial, but consult your doctor before starting any exercise routine.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas.
Avoid cold and sugary drinks that may thicken mucus.
Eat a balanced diet rich in fruits and vegetables.
Limit caffeine intake as it may increase nervousness.
Avoid spicy and oily foods that may irritate the throat.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, tremors, or palpitations, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to inform your employer if your work involves operating heavy machinery.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience severe side effects such as chest pain, irregular heartbeat, or allergic reactions. Do not stop abruptly without medical advice if you have been on long-term therapy.

📅 Long-Term Use Effects

Long-term use of this medicine without medical supervision may lead to tremors, palpitations, hypokalemia, and increased heart rate. It is not recommended for prolonged use unless advised by a doctor. Regular monitoring of heart rate, blood pressure, and serum potassium may be required. Consult your doctor for periodic review.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and relieve congestion.

Evidence: Well-established
Chest physiotherapy

Techniques to help clear mucus from airways.

Evidence: Moderate
Saline nasal irrigation

May help reduce postnasal drip and cough.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your doctor about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep the bottle tightly closed and away from moisture.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis and thick mucus
He was prescribed this medicine three times a day. After two days, he noticed his cough became more productive and breathing improved. He experienced mild tremor initially, which subsided after a day. He was advised to take it with food to avoid stomach upset.
💡 Lesson: This medicine effectively loosens mucus and opens airways, but mild side effects like tremor may occur initially and usually resolve.
👤 A 60-year-old woman with COPD exacerbation
She was given this medicine along with other medications. Her breathing improved, but she felt palpitations. Her doctor reduced the dose and monitored her heart rate. She was advised to avoid caffeine and alcohol.
💡 Lesson: Elderly patients may be more sensitive to cardiovascular side effects; dose adjustment and monitoring are important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 15-30 minutes after oral administration. You may notice relief from cough and easier breathing within a few hours.

Q: Can I take this medicine with food?

A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset.

Q: Is it safe to take this medicine during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. The risk-benefit ratio should be assessed by a qualified clinician.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is only for productive cough with mucus and bronchospasm. It is not effective for dry cough or cough due to other causes.
  • Myth: It is safe to take this medicine for a long time without doctor's advice.
    Fact: Prolonged use without medical supervision can cause side effects like tremors, palpitations, and hypokalemia. Always follow your doctor's advice.
  • Myth: This medicine is safe for children under 2 years.
    Fact: This medicine is not recommended for children under 2 years due to lack of established safety and efficacy.

🔄 Alternative Options

Generic Alternatives

  • Ambroxol + Salbutamol syrup (generic)

Brand Alternatives

  • Ambrodil-S
  • Mucolite-S
  • Bro-Zedex
  • Ascoril
  • Alex
  • Grilinctus

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ambroxol 15mg/5ml + Salbutamol 1mg/5ml","onset":"15-30 minutes","duration":"4-6 hours","key_feature":"Combination mucolytic and bronchodilator"},{"medicine":"Ambroxol alone","composition":"Ambroxol only","onset":"30-60 minutes","duration":"6-8 hours","key_feature":"Mucolytic only, no bronchodilation"},{"medicine":"Salbutamol alone","composition":"Salbutamol only","onset":"15-30 minutes","duration":"4-6 hours","key_feature":"Bronchodilator only, no mucolytic action"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory