Amcidal Syrup: Complete Guide To Uses, Dosage, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain that does not improve
- Seizures or loss of consciousness
- Numbness, tingling, or weakness in the hands or feet
- Severe skin rash, blisters, or peeling skin
- Yellowing of the skin or eyes
- Difficulty breathing or swelling of the face, lips, or throat
- Signs of severe dehydration such as very little urine, dry mouth, or dizziness on standing
If experiencing severe symptoms, call emergency services immediately.
What is amcidal syrup used for?
This medicine is a prescription oral syrup containing furazolidone and metronidazole, used to treat certain infectious diarrheas, giardiasis, and amoebiasis. It works by killing susceptible bacteria and protozoa in the gut. It must be taken exactly as prescribed, and alcohol must be avoided completely during and for three days after treatment.
- Generic Name: Furazolidone + Metronidazole
- Manufacturer: Oyster Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 amcidal syrup के बारे में (Hindi Summary)
उपयोग: यह दवा फ्यूराज़ोलिडोन और मेट्रोनिडाज़ोल का संयोजन है, जिसका उपयोग संक्रामक दस्त, जियार्डिया संक्रमण और अमीबियासिस के इलाज के लिए किया जाता है। यह आंतों में रोग पैदा करने वाले बैक्टीरिया और परजीवियों को मारती है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और पूरा कोर्स पूरा करना जरूरी है। इस दवा के साथ शराब बिल्कुल नहीं लेनी चाहिए, क्योंकि इससे गंभीर प्रतिक्रिया हो सकती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, पेट में असहजता, भूख न लगना, सिरदर्द और मुंह में धातु जैसा स्वाद शामिल हैं। कुछ लोगों का पेशाब गहरा या चाय जैसा दिख सकता है, जो आमतौर पर हानिकारक नहीं होता। दुर्लभ मामलों में हाथ-पैरों में झुनझुनी, सुन्नपन, दौरे, त्वचा पर गंभीर प्रतिक्रिया या खून से जुड़ी समस्याएं हो सकती हैं। अगर ऐसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और पूरा कोर्स पूरा करें, भले ही आराम महसूस होने लगे। इलाज के दौरान और आखिरी खुराक के बाद कम से कम तीन दिन तक शराब और शराब युक्त पदार्थ बिल्कुल न लें। दवा को भोजन या दूध के साथ लें ताकि पेट में जलन कम हो। अगर चक्कर, नींद या अस्थिरता महसूस हो तो वाहन न चलाएं और मशीन न चलाएं। लिवर, किडनी या खून से जुड़ी बीमारी हो तो डॉक्टर को पहले बताएं।
💊 amcidal syrup Uses & Benefits
[{"condition":"Infectious diarrhea","description":"Used to treat diarrhea caused by susceptible bacteria and protozoa when a clinician determines that combination therapy is appropriate.","evidence":"Established for specific susceptible organisms"},{"condition":"Giardiasis","description":"Used to treat intestinal infection caused by Giardia lamblia, a common cause of prolonged watery diarrhea and malabsorption.","evidence":"Established for metronidazole component; combination use varies by region"},{"condition":"Amoebiasis","description":"Used to treat intestinal amoebic infection caused by Entamoeba histolytica, which can cause bloody diarrhea and abdominal pain.","evidence":"Established for metronidazole component; combination use varies by region"},{"condition":"Bacterial enteritis","description":"May be used for selected bacterial causes of enteritis when susceptibility and clinical judgment support combination therapy.","evidence":"Limited and organism-specific"}]
Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Metronidazole is sometimes used as part of combination regimens for H. pylori, but this specific furazolidone-metronidazole syrup is not a standard regimen.","evidence":"Limited and not established for this product"}]
Primary treatment for: Infectious diarrhea
Also treats: Giardiasis, Amoebiasis, Bacterial enteritis
📋 Drug Information
| Generic Name(s) | Furazolidone + Metronidazole |
| Brand Name | Aristogyl-F Oral Suspension |
| Manufacturer | Oyster Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibacterial, Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the bottle tightly closed and do not freeze. Keep out of reach of children. |
| Shelf Life | Refer to the expiry date printed on the pack. Do not use after the expiry date. Once opened, use within the period recommended by the manufacturer or pharmacist. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antimicrobial agents with different mechanisms. Furazolidone is reduced inside susceptible microorganisms to reactive intermediates that damage bacterial and protozoal enzymes and DNA. Metronidazole enters susceptible anaerobic organisms and protozoa, where its nitro group is reduced to reactive compounds that break DNA strands and inhibit nucleic acid synthesis. Together, these actions stop the growth of susceptible bacteria and protozoa in the gastrointestinal tract.
Mechanism Steps
💡 How to Take amcidal syrup
Strength: Each 5 mL of syrup contains furazolidone 50 mg and metronidazole 100 mg.
Dosage Information
| Adult Dosage | The dose of this medicine is determined by your doctor based on the type and severity of infection, your age, weight, kidney and liver function, and other medicines you are taking. It is usually taken two to three times a day with food or milk. Do not change the dose or frequency on your own. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially dizziness, confusion, and peripheral neuropathy. Kidney and liver function should be assessed before and during treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Renal Impairment | This medicine is partly excreted by the kidneys. In severe kidney disease, dose adjustment or an alternative medicine may be needed. Your doctor will decide the appropriate dose based on your kidney function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Hepatic Impairment | This medicine is metabolized in the liver, and liver disease can increase the risk of side effects. In severe liver disease, this medicine is usually avoided. Your doctor will decide if dose adjustment or an alternative medicine is needed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Maximum Daily Dose | The maximum daily dose is determined by your doctor based on your condition and response to treatment. Do not exceed the prescribed dose. Specific maximum daily dose limits for this combination syrup are not established from the available information. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of amcidal syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Warfarin | Major | |
| Disulfiram | Major | |
| Lithium | Major | |
| Phenytoin | Major | |
| Phenobarbital | Major | |
| Fluorouracil | Moderate | |
| Cimetidine | Moderate | |
| Cyclosporine | Moderate | |
| Tacrolimus | Moderate |
🚨 Major Interactions
- Alcohol and alcohol-containing products
- Warfarin and other oral anticoagulants
- Disulfiram
- Lithium
- Phenytoin and phenobarbital
⚡ Moderate Interactions
- Fluorouracil
- Cimetidine
- Cyclosporine
- Tacrolimus
- Carbamazepine
🍷 Alcohol Interaction
Alcohol must be completely avoided while taking this medicine and for at least three days after the last dose. Combining alcohol with this medicine can cause a disulfiram-like reaction with flushing, palpitations, severe nausea, vomiting, headache, and low blood pressure. In severe cases, this reaction can be dangerous and requires urgent medical attention.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to furazolidone, metronidazole, or any other ingredient","Pregnancy","Breastfeeding","Consumption of alcohol or alcohol-containing products within the last three days","Use of disulfiram within the last two weeks","Severe liver disease","Certain nervous system disorders","Children under the age recommended by the prescribing doctor"]
⚠️ Warnings & Precautions
["Avoid all alcohol during treatment and for at least three days after the last dose.","Do not drive or operate heavy machinery if you feel dizzy, drowsy, or unsteady.","Inform your doctor if you have liver disease, kidney disease, or a blood disorder.","Report numbness, tingling, or weakness in the hands or feet promptly.","Do not use this medicine for viral diarrhea or non-infectious diarrhea.","Complete the full course prescribed by your doctor even if symptoms improve.","Keep out of reach of children and store as directed on the label.","Tell your doctor about all other medicines you are taking, including over-the-counter products."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding. Metronidazole passes into breast milk and may affect the nursing infant. If treatment is essential, your doctor may advise temporarily stopping breastfeeding or using an alternative medicine. Discuss all options with your doctor before starting this medicine.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, abdominal pain, dizziness, and in serious cases, seizures or blood disorders. If you suspect an overdose, contact your doctor or a poison control center immediately. Do not try to induce vomiting unless instructed by a medical professional. Treatment is supportive and may include monitoring of vital signs, blood tests, and management of specific symptoms.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for the next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor and complete the full course even if you feel better. Avoid all alcohol and alcohol-containing products during treatment and for at least three days after the last dose, because a serious reaction can occur. Take the syrup with food or milk to reduce stomach upset. Do not drive or operate heavy machinery if you feel dizzy, drowsy, or unsteady. Inform your doctor if you have liver disease, kidney disease, a blood disorder, or a nervous system condition before starting this medicine. Do not share this medicine with anyone else, even if they have similar symptoms. Keep it out of reach of children and store it as directed on the label. If you miss a dose, follow your doctor's instructions and do not double the next dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to the side effects of this medicine, especially dizziness, confusion, and peripheral neuropathy. Kidney and liver function should be assessed before and during treatment. The dose may need to be adjusted based on kidney and liver function. Older adults should also be monitored for dehydration, which can worsen quickly during diarrhea.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are pregnant or planning to become pregnant. Both furazolidone and metronidazole may pose risks to the developing fetus. If you are trying to conceive, discuss alternative treatments with your doctor. Use effective contraception during treatment and for a period advised by your doctor.
🏥 Post-Surgery Considerations
If you have recently had surgery, inform your surgeon and anesthesiologist that you are taking this medicine. This medicine can interact with other medicines used during and after surgery, and it may affect recovery. Do not start or stop this medicine around the time of surgery without your doctor's advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine can interact with other medicines and may affect bleeding risk if you are also taking blood thinners. Your dentist may recommend postponing non-urgent dental work until you have completed the course and recovered.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while you have diarrhea or feel weak, dizzy, or dehydrated. Light activity such as short walks may be fine if you feel well. Do not drive or operate heavy machinery if you feel dizzy, drowsy, or unsteady. Resume your normal exercise routine only after you have recovered and your doctor says it is safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or unsteadiness in some people. Avoid driving, operating heavy machinery, or doing tasks that require full alertness until you know how the medicine affects you. Diarrhea itself can cause weakness and dehydration, so take rest breaks and stay hydrated. Inform your employer if you need time off to recover, especially if your work involves food handling or close contact with others.
🛑 When to Stop This Medicine
Stop this medicine only after completing the full course prescribed by your doctor. Do not stop early even if you feel better, because the infection may return. If you develop a serious side effect such as numbness or tingling, seizures, severe skin rash, or yellowing of the skin or eyes, stop the medicine and seek medical care immediately. Do not restart the medicine without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not usually recommended. Prolonged use can increase the risk of peripheral neuropathy, blood disorders, and liver injury. If treatment is needed for more than a few days, your doctor may monitor your blood counts, liver function, and nervous system. Do not use this medicine for longer than prescribed without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Replaces fluids and electrolytes lost through diarrhea and is essential supportive care.
Evidence: Well-establishedMay reduce the duration and severity of diarrhea in some patients, especially children, when advised by a doctor.
Evidence: Established in specific populationsMay help restore gut bacteria after infection, but evidence varies by strain and condition.
Evidence: Limited to moderateBland, easy-to-digest foods can help reduce symptoms while the infection clears.
Evidence: Well-established as supportive care💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions established for this medicine. However, if you are due for any vaccine, inform your doctor that you are taking this medicine. Live vaccines may need to be postponed in some situations, so always discuss your vaccination schedule with your doctor.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not freeze or refrigerate unless specified
✅ DO
Keep the bottle tightly closed in its original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription with you in case customs or security officials ask for it. Store the bottle at room temperature, away from direct sunlight and heat, and do not leave it in a hot car. If you are crossing time zones, ask your doctor how to adjust the dosing schedule. Continue to avoid alcohol completely during travel and for three days after the last dose. If you develop severe diarrhea, dehydration, or any red-flag symptoms while traveling, seek medical care promptly.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Symptom improvement may begin within 24 to 48 hours, but you must complete the full course prescribed by your doctor to prevent relapse.
A: No. Alcohol must be completely avoided during treatment and for at least three days after the last dose because it can cause a serious disulfiram-like reaction.
A: If you remember within half the dosing interval, take the missed dose. If more than half the interval has passed, skip it and continue with your regular schedule. Do not double dose.
A: Pediatric dosing is not established from available information. Only a pediatrician can decide if this medicine is appropriate for a child and at what dose.
A: No. Stopping early can allow the infection to return and may promote resistance. Complete the full course prescribed by your doctor.
A: Watch for numbness or tingling in the hands or feet, seizures, severe skin reactions, unusual bruising or bleeding, and yellowing of the skin or eyes. Seek medical care promptly if any of these occur.
🤔 Common Patient Concerns
🔄 Substitutes for amcidal syrup
View AllAlternative brands with exact same active ingredient:
-
metromed suspensionIndamed Pharmaceuticals Pvt Ltd ₹12.10 34.6% CHEAPER
-
prozyl f syrupAcron Pharmaceuticals ₹15.00 18.9% CHEAPER
-
amcidal suspensionOyster Labs Ltd ₹60.00 224.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped as soon as diarrhea stops.
Fact: Stopping early can allow the infection to return and may promote resistance. Complete the full course prescribed by your doctor. - Myth: This medicine can be taken with alcohol without any problem.
Fact: Alcohol can cause a serious disulfiram-like reaction with flushing, palpitations, nausea, and vomiting. Avoid alcohol completely during and for three days after treatment. - Myth: This medicine is safe for everyone with diarrhea.
Fact: This medicine is only for specific infectious causes of diarrhea and is not suitable for everyone. It should only be used when prescribed by a doctor. - Myth: This medicine can be used during pregnancy without risk.
Fact: This medicine is not recommended during pregnancy. Inform your doctor if you are pregnant or planning pregnancy.
🔄 Alternative Options
Generic Alternatives
- Furazolidone and metronidazole oral suspension
- Furazolidone oral suspension
- Metronidazole oral suspension