amalzol-l capsule sr - Uses, Price, Side Effects & Substitutes
What is amalzol-l capsule sr used for?
Aciban L 75 mg/40 mg Capsule (Levosulpiride + Pantoprazole) is used to treat GASTRO INTESTINAL. It contains Levosulpiride (75mg) + Pantoprazole (40mg), which Levosulpiride: Blocks dopamine D2 receptors in GI tract, enhancing motility; Pan. Always consult your doctor before use. Take as prescribed.
- Generic Name: Levosulpiride + Pantoprazole
- Manufacturer: Superlative Healthcare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ amalzol-l capsule sr Uses & Benefits
Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis
Off-label uses: Functional dyspepsia, diabetic gastroparesis
๐ Drug Information
| Generic Name(s) | Levosulpiride + Pantoprazole |
| Brand Name | Aciban L 75 mg/40 mg Capsule |
| Manufacturer | Superlative Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Levosulpiride: Blocks dopamine D2 receptors in GI tract, enhancing motility; Pantoprazole: Irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reducing acid secretion
Mechanism Steps
๐ก How to Take amalzol-l capsule sr
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of amalzol-l capsule sr
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Dizziness
๐จ Serious Side Effects
- QT prolongation
- Tardive dyskinesia
- Clostridium difficile infection
- Bone fracture
โ ๏ธ Rare Side Effects
- Gynecomastia
- Galactorrhea
- Interstitial nephritis
- Hepatotoxicity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased INR and bleeding risk |
| Clopidogrel | Major | Reduced clopidogrel efficacy |
| Methotrexate | Major | Increased methotrexate toxicity |
| Ketoconazole | Moderate | Reduced ketoconazole absorption |
| Digoxin | Moderate | Possible increased digoxin levels |
| Fluconazole | Major | Increased pantoprazole levels |
| Rifampin | Major | Decreased pantoprazole efficacy |
๐จ Major Interactions
- CYP2C19 inhibitors (e.g., fluconazole)
- CYP2C19 inducers (e.g., rifampin)
- Methotrexate
- Clopidogrel
โก Moderate Interactions
- Anticoagulants (warfarin)
- Digoxin
- Ketoconazole
- Iron salts
โน๏ธ Minor Interactions
- Sucralfate
- Antacids
๐ฝ๏ธ Food Interactions
Food delays absorption of pantoprazole; levosulpiride absorption unaffected
๐ท Alcohol Interaction
May increase risk of GI irritation; avoid alcohol
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, GI obstruction, hemorrhage, perforation, concomitant use with clopidogrel (for pantoprazole)
๐ Monitoring Parameters
Liver function, renal function, serum electrolytes, ECG (QT interval)
๐คฑ Lactation Safety
Caution; levosulpiride excreted in milk, pantoprazole unknown
๐ Overdose Management
Symptomatic and supportive; no specific antidote
โฐ Missed Dose
Take as soon as remembered; skip if near next dose