amalzol-dsr capsule - Uses, Price, Side Effects & Substitutes
What is amalzol-dsr capsule used for?
Anleo-DSR Capsule (Domperidone + Pantoprazole) is used to treat Gastroesophageal reflux disease (GERD). It contains Domperidone (30mg) + Pantoprazole (40mg), which Domperidone is a dopamine D2 receptor antagonist that enhances gastric motility . Always consult your doctor before use. Take as prescribed.
- Generic Name: Domperidone + Pantoprazole
- Manufacturer: Superlative Healthcare
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 amalzol-dsr capsule के बारे में संक्षिप्त जानकारी (Hindi Summary)
amalzol-dsr capsule का उपयोग मुख्य रूप से gastro intestinal और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Domperidone (30mg) + Pantoprazole (40mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Domperidone + Pantoprazole |
|---|---|
| Brand Name | Anleo-DSR Capsule |
| Manufacturer | Superlative Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from moisture and light. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take amalzol-dsr capsule?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from moisture and light.
⚙️ How amalzol-dsr capsule Works
Domperidone is a dopamine D2 receptor antagonist that enhances gastric motility and accelerates gastric emptying. Pantoprazole is a proton pump inhibitor that irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reducing gastric acid secretion.
💊 amalzol-dsr capsule Uses in Hindi (Ke Fayde), Benefits & Indications
Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, peptic ulcer disease, Zollinger-Ellison syndrome (pantoprazole component).
Off-label uses: Domperidone: Lactation stimulation (not approved in many countries); Pantoprazole: Prevention of stress ulcers, eosinophilic esophagitis.
⚠️ What are the side effects of amalzol-dsr capsule?
✅ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Flatulence
- Dry mouth
- Dizziness
🚨 Serious Side Effects
- QT prolongation
- Ventricular arrhythmias
- Extrapyramidal symptoms (domperidone)
- Clostridium difficile infection
- Bone fracture (long-term)
- Hypomagnesemia
- Interstitial nephritis
⚠️ Rare Side Effects
- Gynecomastia
- Galactorrhea
- Jaundice
- Hepatitis
- Anaphylaxis
- Stevens-Johnson syndrome
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased risk of QT prolongation |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Sucralfate | Minor | Reduced absorption of pantoprazole |
🚨 Major Interactions
- Ketoconazole
- Itraconazole
- Voriconazole
- Clarithromycin
- Erythromycin
- Ritonavir
- Saquinavir
- Amiodarone
- Quinidine
- Methotrexate
⚡ Moderate Interactions
- Warfarin
- Cilostazol
- Citalopram
- Escitalopram
- Fluoxetine
- Paroxetine
- Sertraline
- Tacrolimus
- Cyclosporine
- Digoxin
ℹ️ Minor Interactions
- Sucralfate
- Antacids
- Iron supplements
- Calcium carbonate
🍽️ Food Interactions
Food delays absorption of domperidone; pantoprazole should be taken before meals for optimal effect.
🍷 Alcohol Interaction
Alcohol may worsen gastrointestinal irritation and reduce drug efficacy.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to any component; gastrointestinal hemorrhage, obstruction, or perforation; prolactinoma; concurrent use with strong CYP3A4 inhibitors (e.g., ketoconazole) causing QT prolongation; severe hepatic impairment.
📊 Monitoring Parameters
Liver function tests, ECG (QT interval), serum electrolytes, magnesium levels (long-term use), renal function.
🤱 Lactation Safety
Domperidone is excreted in breast milk; pantoprazole is excreted in small amounts. Caution advised.
💊 Overdose Management
Supportive care; domperidone overdose may cause extrapyramidal symptoms; pantoprazole overdose unlikely to cause serious effects.
⏰ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose.
🛑 Myths vs. Facts about amalzol-dsr capsule
- Myth: Generic substitutes of amalzol-dsr capsule are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Domperidone (30mg) + Pantoprazole (40mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of amalzol-dsr capsule can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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