afineday tablet - Montelukast (10mg) + Fexofenadine (120mg) medicine

afineday tablet

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🏭 Indchemie Health Specialities Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is afineday tablet used for?

This medicine contains Montelukast (10mg) + Fexofenadine (120mg) and is used to treat RESPIRATORY. Montelukast selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor CysLT1, red. Always consult your doctor before use.

  • Generic Name: Montelukast + Fexofenadine
  • Manufacturer: Indchemie Health Specialities Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 afineday tablet Uses & Benefits

Seasonal allergic rhinitis, perennial allergic rhinitis, asthma prophylaxis, urticaria.

Off-label uses: Exercise-induced bronchoconstriction (montelukast), chronic urticaria.

📋 Drug Information

Generic Name(s)Montelukast + Fexofenadine
Brand NameAir-M Tablet
ManufacturerIndchemie Health Specialities Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassLeukotriene receptor antagonist + Antihistamine
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMontelukast: rapidly absorbed after oral administration; Fexofenadine: well absorbed after oral administration.
DistributionMontelukast: extensively distributed; Fexofenadine: distributed into tissues.
Protein BindingMontelukast: >99% bound to plasma proteins; Fexofenadine: 60-70% bound to plasma proteins.
MetabolismMontelukast: extensively metabolized by CYP3A4 and CYP2C9; Fexofenadine: minimally metabolized.
Half-LifeMontelukast: 2.7-5.5 hours; Fexofenadine: 14.4 hours.
ExcretionMontelukast: primarily via feces; Fexofenadine: primarily via feces (80%) and urine (11%).
BioavailabilityMontelukast: 64% (oral); Fexofenadine: 33% (oral).
Onset of ActionMontelukast: within hours; Fexofenadine: 1-2 hours.
Peak Plasma TimeMontelukast: 2-4 hours; Fexofenadine: 2-3 hours.
Duration of ActionMontelukast: 24 hours; Fexofenadine: 24 hours.

How It Works

Montelukast selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor CysLT1, reducing airway edema, smooth muscle contraction, and inflammatory cell activity. Fexofenadine is a peripherally selective histamine H1 receptor antagonist, inhibiting histamine-mediated allergic responses.

Mechanism Steps

1Montelukast binds to CysLT1 receptor, blocking leukotriene D4 action.
2Reduces bronchoconstriction, mucus secretion, and airway inflammation.
3Fexofenadine selectively blocks peripheral H1 receptors.
4Inhibits histamine-induced vasodilation, increased vascular permeability, and sensory nerve stimulation.
5Combined effect alleviates allergic symptoms and improves asthma control.

💡 How to Take afineday tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of afineday tablet

✅ Common Side Effects

Headache
Dizziness
Nausea
Diarrhea
Fatigue
Cough
Pharyngitis

🚨 Serious Side Effects

Anaphylaxis
Angioedema
Severe skin reactions (e.g., eosinophilic granulomatosis with polyangiitis)
Hepatic dysfunction

⚠️ Rare Side Effects

Seizures
Thrombocytopenia
Hallucinations
Churg-Strauss syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major Increased montelukast levels
Rifampin Major Decreased montelukast efficacy
Erythromycin Moderate Increased fexofenadine levels
Warfarin Moderate Possible increased INR
Fruit juices Minor Reduced fexofenadine absorption

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP2C9 inhibitors (e.g., fluconazole)
  • Rifampin
  • Phenobarbital

⚡ Moderate Interactions

  • Erythromycin
  • Gemfibrozil
  • Warfarin

🍷 Alcohol Interaction

Alcohol may potentiate CNS depression; caution advised.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to any component.

🤱 Lactation Safety

Montelukast: excreted in breast milk; Fexofenadine: excreted in breast milk; caution advised.

💊 Overdose Management

Symptomatic and supportive treatment; no specific antidote.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

🔄 Substitutes for afineday tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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