acolate lp 2.5mg/10mg tablet - Levocetirizine (2.5mg) + Phenylephrine (10mg) medicine

acolate lp 2.5mg/10mg tablet

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🏭 Gujarat Terce Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is acolate lp 2.5mg/10mg tablet used for?

This medicine contains Levocetirizine (2.5mg) + Phenylephrine (10mg) and is used to treat RESPIRATORY. Levocetirizine: selective H1-receptor antagonist; Phenylephrine: alpha-1 adrenergic receptor agonist. Always consult your doctor before use.

  • Generic Name: Levocetirizine + Phenylephrine
  • Manufacturer: Gujarat Terce Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 acolate lp 2.5mg/10mg tablet Uses & Benefits

Allergic rhinitis, common cold symptoms (nasal congestion, sneezing, runny nose)

Off-label uses: Urticaria, chronic idiopathic urticaria (levocetirizine alone)

📋 Drug Information

Generic Name(s)Levocetirizine + Phenylephrine
Brand NameAllercet Cold Tablet
ManufacturerGujarat Terce Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Decongestant
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract
DistributionWidely distributed; crosses blood-brain barrier minimally for levocetirizine
Protein BindingLevocetirizine: ~91-92%; Phenylephrine: minimal
MetabolismLevocetirizine: minimal hepatic metabolism; Phenylephrine: hepatic via MAO
Half-LifeLevocetirizine: 7-8 hours; Phenylephrine: 2-3 hours
ExcretionLevocetirizine: primarily renal (85%); Phenylephrine: renal
BioavailabilityLevocetirizine: high; Phenylephrine: ~38%
Onset of ActionLevocetirizine: 1 hour; Phenylephrine: 15-30 minutes
Peak Plasma TimeLevocetirizine: 0.9 hours; Phenylephrine: 1-2 hours
Duration of ActionLevocetirizine: 24 hours; Phenylephrine: 4-6 hours

How It Works

Levocetirizine: selective H1-receptor antagonist; Phenylephrine: alpha-1 adrenergic receptor agonist

Mechanism Steps

1Levocetirizine binds to H1 receptors, blocking histamine action, reducing allergic symptoms.
2Phenylephrine activates alpha-1 adrenergic receptors on nasal blood vessels, causing vasoconstriction and decongestion.

💡 How to Take acolate lp 2.5mg/10mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of acolate lp 2.5mg/10mg tablet

✅ Common Side Effects

Somnolence
Fatigue
Dry mouth
Headache
Nervousness
Insomnia

🚨 Serious Side Effects

Hypertension
Tachycardia
Palpitations
Allergic reactions
Urinary retention

⚠️ Rare Side Effects

Seizures
Arrhythmias
Hepatotoxicity
Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major Hypertensive crisis
Beta-blockers Moderate Reduced decongestant effect, bradycardia
Tricyclic antidepressants Moderate Increased risk of hypertension and arrhythmias
Alcohol Minor Increased sedation

🚨 Major Interactions

  • MAOIs
  • Rasagiline
  • Selegiline
  • Linezolid
  • Methylene Blue

⚡ Moderate Interactions

  • Beta-blockers
  • Tricyclic antidepressants
  • Sympathomimetics
  • Ergot alkaloids

🍷 Alcohol Interaction

Increased CNS depression; avoid concurrent use

🛡️ Safety & Warnings

🚫 Contraindications

Severe hypertension, coronary artery disease, MAOI use, narrow-angle glaucoma, urinary retention

🤱 Lactation Safety

Levocetirizine: excreted in milk, use caution; Phenylephrine: limited data, avoid

💊 Overdose Management

Supportive care; for phenylephrine: phentolamine for hypertension; for levocetirizine: symptomatic

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

🔄 Substitutes for acolate lp 2.5mg/10mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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