alvikof plus tablet - Caffeine (30mg) + Chlorpheniramine Maleate (2mg) medicine

alvikof plus tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Alvid Biocare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is alvikof plus tablet used for?

Almolet Tablet (Caffeine + Chlorpheniramine Maleate) is used to treat RESPIRATORY. It contains Caffeine (30mg) + Chlorpheniramine Maleate (2mg), which Caffeine: Adenosine receptor antagonist; Chlorpheniramine: H1-receptor antagonis. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Caffeine + Chlorpheniramine Maleate
  • Manufacturer: Alvid Biocare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š alvikof plus tablet Uses & Benefits

Symptomatic relief of allergic rhinitis, common cold, sinusitis.

Off-label uses: None well-established.

๐Ÿ“‹ Drug Information

Generic Name(s)Caffeine + Chlorpheniramine Maleate
Brand NameAlmolet Tablet
ManufacturerAlvid Biocare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + CNS Stimulant
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract.
DistributionDistributes widely throughout the body; crosses blood-brain barrier.
Protein BindingCaffeine: ~35%; Chlorpheniramine: ~70%
MetabolismCaffeine: Hepatic (CYP1A2); Chlorpheniramine: Hepatic (CYP2D6, CYP3A4)
Half-LifeCaffeine: 3-5 hours; Chlorpheniramine: 14-24 hours
ExcretionCaffeine: Renal (primarily as metabolites); Chlorpheniramine: Renal
BioavailabilityCaffeine: ~100%; Chlorpheniramine: ~25-50%
Onset of ActionCaffeine: 15-45 minutes; Chlorpheniramine: 30-60 minutes
Peak Plasma TimeCaffeine: 1-2 hours; Chlorpheniramine: 2-6 hours
Duration of ActionCaffeine: 4-6 hours; Chlorpheniramine: 4-6 hours

How It Works

Caffeine: Adenosine receptor antagonist; Chlorpheniramine: H1-receptor antagonist

Mechanism Steps

1Caffeine blocks adenosine receptors (A1 and A2A), reducing inhibitory neurotransmission and causing CNS stimulation.
2Chlorpheniramine competitively blocks histamine at H1 receptors, reducing allergic symptoms.
3Combination provides relief of cold and allergy symptoms with reduced drowsiness due to caffeine.

๐Ÿ’ก How to Take alvikof plus tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of alvikof plus tablet

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Nervousness
  • Insomnia
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Severe allergic reactions
  • Arrhythmias
  • Seizures
  • Urinary retention

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Hepatotoxicity
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Increased risk of hypertensive crisis
Fluvoxamine Major Increased caffeine toxicity
Alcohol Moderate Enhanced sedation
Sedatives Moderate Additive CNS depression
Anticholinergics Moderate Increased anticholinergic effects

๐Ÿšจ Major Interactions

  • MAOIs
  • CYP1A2 inhibitors (e.g., fluvoxamine)
  • CYP2D6 inhibitors (e.g., paroxetine)

โšก Moderate Interactions

  • Alcohol
  • Sedatives
  • Anticholinergics

โ„น๏ธ Minor Interactions

  • Theophylline
  • Disulfiram

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase caffeine levels.

๐Ÿท Alcohol Interaction

Increased sedation and CNS depression.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe hypertension, hyperthyroidism, glaucoma, urinary retention, concurrent MAOI use.

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, CNS effects, anticholinergic effects.

๐Ÿคฑ Lactation Safety

Caffeine and chlorpheniramine are excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; activated charcoal may be considered; monitor for CNS stimulation and arrhythmias.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

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