alphadol 0.5mcg soft gelatin capsule
What is alphadol 0.5mcg soft gelatin capsule used for?
Alphadol (Alfacalcidol) is used to treat VITAMINS MINERALS NUTRIENTS. It contains Alfacalcidol (0.5mcg), which Alfacalcidol is a prodrug that is hydroxylated in the liver to form calcitriol, . Always consult your doctor before use. Take as prescribed.
- Generic Name: Alfacalcidol
- Manufacturer: Panacea Biotec Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ alphadol 0.5mcg soft gelatin capsule Uses & Benefits
Osteoporosis, renal osteodystrophy, hypoparathyroidism, rickets, osteomalacia.
Off-label uses: Psoriasis, autoimmune diseases (limited evidence).
๐ Drug Information
| Generic Name(s) | Alfacalcidol |
| Brand Name | Alphadol |
| Manufacturer | Panacea Biotec Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Vitamins |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Alfacalcidol is a prodrug that is hydroxylated in the liver to form calcitriol, which binds to vitamin D receptors (VDR) in target tissues, regulating calcium and phosphate homeostasis.
Mechanism Steps
๐ก How to Take alphadol 0.5mcg soft gelatin capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of alphadol 0.5mcg soft gelatin capsule
โ Common Side Effects
- Hypercalcemia
- Hypercalciuria
- Nausea
- Vomiting
- Constipation
- Headache
๐จ Serious Side Effects
- Severe hypercalcemia
- Arrhythmias
- Renal impairment
- Bone pain
โ ๏ธ Rare Side Effects
- Allergic reactions
- Metastatic calcification
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Thiazide diuretics | Major | Increased risk of hypercalcemia |
| Cardiac glycosides | Major | Increased risk of arrhythmias due to hypercalcemia |
| Cholestyramine | Major | Reduced absorption of alfacalcidol |
| Phenytoin | Moderate | Reduced efficacy of alfacalcidol |
| Corticosteroids | Moderate | Reduced calcium absorption |
๐จ Major Interactions
- Thiazide diuretics
- Cardiac glycosides (e.g., digoxin)
- Cholestyramine
- Colestipol
- Orlistat
- Mineral oil
โก Moderate Interactions
- Phenytoin
- Phenobarbital
- Carbamazepine
- Corticosteroids
- Rifampin
- Isoniazid
โน๏ธ Minor Interactions
- Magnesium-containing antacids
- Aluminum-containing antacids
- Calcium supplements
๐ฝ๏ธ Food Interactions
May be taken with or without food; high-fiber diets may reduce absorption.
๐ท Alcohol Interaction
No significant interaction reported.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypercalcemia, hypercalciuria, vitamin D toxicity, known hypersensitivity.
๐ Monitoring Parameters
Serum calcium, phosphate, alkaline phosphatase, and renal function periodically.
๐คฑ Lactation Safety
Excreted in breast milk; caution advised.
๐ Overdose Management
Discontinue drug; treat hypercalcemia with hydration, loop diuretics, corticosteroids, and calcitonin if severe.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for alphadol 0.5mcg soft gelatin capsule
View AllAlternative brands with exact same active ingredient (Alfacalcidol (0.5mcg)):
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.