airyfen 1mg tablet - Ketotifen (1mg) medicine

Asthafen Syrup (Ketotifen): Complete Medicine Guide

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🏭 Panacea Biotec Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 22, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic conditions.
Reviewed by
SaathiMed Expert Panel | Sep 22, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe drowsiness or confusion
  • Yellowing of skin or eyes
  • Unusual bleeding or bruising
  • Seizures
  • Severe abdominal pain

If experiencing severe symptoms, call emergency services immediately.

What is airyfen 1mg tablet used for?

This medicine is an antihistamine syrup containing ketotifen, used to treat allergic conditions like hay fever, hives, and itchy eyes. It works by blocking histamine and stabilizing mast cells. It may cause drowsiness, so avoid driving. Take as prescribed by your doctor.

  • Generic Name: Ketotifen
  • Manufacturer: Panacea Biotec Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 airyfen 1mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी से होने वाली समस्याओं जैसे नाक बहना, छींक आना, आंखों में खुजली और पानी आना, त्वचा पर चकत्ते और खुजली के इलाज में उपयोग की जाती है। यह एलर्जी पैदा करने वाले पदार्थों को रोककर काम करती है। यह बच्चों और बड़ों दोनों के लिए उपलब्ध है।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुंह सूखना, सिरदर्द और थकान शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन अगर आपको सांस लेने में कठिनाई, चेहरे पर सूजन, या पीलिया जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसकी मात्रा न बढ़ाएं। इस दवा को लेने के बाद नींद आ सकती है, इसलिए गाड़ी चलाने या मशीन चलाने से बचें। शराब का सेवन न करें क्योंकि इससे नींद और बढ़ सकती है। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 airyfen 1mg tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Allergic conjunctivitis","description":"Reduces itching, redness, and tearing of the eyes due to allergic reactions.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps relieve itching and hives associated with chronic or acute urticaria.","evidence":"Well-established"},{"condition":"Atopic dermatitis","description":"May reduce itching associated with eczema, though it is not a primary treatment.","evidence":"Limited"},{"condition":"Mastocytosis","description":"Used to control symptoms related to mast cell activation, such as flushing, itching, and abdominal pain.","evidence":"Limited"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, especially in children, due to its mast cell stabilizing properties.","evidence":"Limited"},{"condition":"Irritable bowel syndrome","description":"May be used off-label to reduce abdominal pain and bloating associated with IBS, but evidence is weak.","evidence":"Insufficient"}]

Primary treatment for: Allergic rhinitis

Also treats: Allergic conjunctivitis, Urticaria, Atopic dermatitis

📋 Drug Information

Generic Name(s)Ketotifen
Brand NameAsthafen Syrup
ManufacturerPanacea Biotec Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMast cell stabilizers
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent levels.
2
Use the provided measuring cup to ensure accurate dosing.
3
Avoid driving or operating machinery until you know how this medicine affects you.
4
Do not use this medicine for acute asthma attacks; use your rescue inhaler instead.
5
Inform your doctor if you experience persistent drowsiness or weight gain.
6
Keep a record of your symptoms to help your doctor assess the effectiveness.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Sneezing and runny nose
This medicine is commonly prescribed for allergic rhinitis.
Likely Use
Itchy eyes
This medicine helps relieve allergic conjunctivitis symptoms.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Acute asthma attack
This medicine is not for acute asthma attacks.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionKetotifen is rapidly absorbed after oral administration. Bioavailability is approximately 50% due to first-pass metabolism.
DistributionKetotifen is widely distributed in body tissues. It crosses the blood-brain barrier and is excreted in breast milk.
Protein BindingApproximately 75% bound to plasma proteins.
MetabolismExtensively metabolized in the liver, primarily by glucuronidation and demethylation. One active metabolite, nor-ketotifen, has some antihistaminic activity.
Half-LifeThe elimination half-life is approximately 12 hours in adults, but may be prolonged in the elderly and in patients with hepatic or renal impairment.
ExcretionKetotifen and its metabolites are excreted mainly in the urine (60-70%) and feces (30-40%).
BioavailabilityApproximately 50%
Onset of ActionOnset of action is within 1-2 hours after oral administration.
Peak Plasma TimePeak plasma concentrations are reached within 2-4 hours.
Duration of ActionThe duration of action is approximately 12-24 hours, allowing for once or twice daily dosing.

How It Works

Ketotifen is a non-competitive histamine H1 receptor antagonist and mast cell stabilizer. It inhibits the release of histamine and other mediators from mast cells, and also blocks H1 receptors, reducing allergic symptoms. Additionally, it may have some anti-inflammatory effects.

Mechanism Steps

1
Mast cell stabilization: Ketotifen prevents the release of histamine and other inflammatory mediators from mast cells, reducing allergic responses.
2
H1 receptor antagonism: It competitively blocks histamine H1 receptors on target cells, alleviating symptoms like itching, sneezing, and vasodilation.
3
Central nervous system effects: Ketotifen crosses the blood-brain barrier and blocks central H1 receptors, leading to sedation and appetite stimulation.

💡 How to Take airyfen 1mg tablet

Strength: Ketotifen 1 mg per 5 mL syrup

1Shake the bottle well before use.
2Use the measuring cup or spoon provided to measure the correct dose.
3Take orally, with or without food.
4Follow your doctor's instructions carefully.
5Do not exceed the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 1 mg (5 mL of syrup) twice daily, with or without food. Dose may be adjusted by the doctor based on the condition and response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosageFor children aged 6 months to 3 years, the usual dose is 0.5 mg (2.5 mL) twice daily. For children over 3 years, the dose may be 1 mg (5 mL) twice daily. Pediatric dosing is not established from available information for all age groups. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the sedative effects. Start with a lower dose and adjust as needed. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment provided. Use with caution in renal impairment. Consult your doctor.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose reduction may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 2 mg for adults, but may be higher under medical supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Can be taken with or without food
Food does not significantly affect absorption.
Alcohol
Avoid
May increase sedation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of airyfen 1mg tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult doctor if severe.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent.
Fatigue (Common (5-10%))
Ensure adequate rest. Consult doctor if it interferes with daily activities.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, tongue, or throat, difficulty breathing, or severe rash.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Blood disorders (e.g., thrombocytopenia, leukopenia) (Rare (<0.1%))
Report unusual bleeding, bruising, or signs of infection to your doctor.

⚠️ Rare Side Effects

Seizures
Seek immediate medical attention.
Hepatitis
Seek immediate medical attention if symptoms of liver injury occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
Warfarin Major
Benzodiazepines Major
Tricyclic antidepressants Moderate
Metformin Moderate
Ketoconazole Minor

🚨 Major Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)
  • Oral anticoagulants (e.g., warfarin)

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., tricyclic antidepressants, antihistamines)
  • Metformin

🍷 Alcohol Interaction

Alcohol may enhance the sedative effects of ketotifen. Avoid concurrent use.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to ketotifen or any component of the syrup","Acute asthma attacks","Severe hepatic impairment"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until effects are known.","Avoid alcohol and other CNS depressants.","Use with caution in patients with epilepsy, hepatic impairment, or renal impairment.","Not for acute asthma attacks.","May cause weight gain; monitor weight.","Safety and efficacy in children under 6 months not established."]

🤱 Lactation Safety

Ketotifen is excreted in breast milk. Caution is advised when used during breastfeeding. Consult your doctor.

💊 Overdose Management

Symptoms of overdose may include severe drowsiness, confusion, tachycardia, and hypotension. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid consuming alcohol or other central nervous system depressants while taking this medicine, as they can increase drowsiness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for acute asthma attacks. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to sedation and anticholinergic effects. Use with caution and lower doses may be needed.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine, as it may interact with anesthetic agents and increase sedation.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental problems.

💚 Lifestyle Tips for Better Results

🏃
Identify and avoid allergens that trigger your symptoms.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Maintain a healthy weight to reduce overall inflammation.
💧
Get adequate sleep to support immune function.
🧘
Practice stress-reducing techniques like yoga or meditation.

🏋️ Exercise Considerations

This medicine may cause drowsiness, so avoid strenuous exercise until you know how it affects you. Stay hydrated during exercise.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Eat plenty of fruits and vegetables rich in antioxidants.
Reduce intake of processed foods and added sugars.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is best to take it at bedtime if it makes you sleepy. Inform your employer if your job involves operating heavy machinery.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor may taper the dose gradually.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, weight gain, and rarely liver enzyme elevations. Regular monitoring of liver function and weight is advised. Do not stop abruptly without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Identifying and avoiding allergens can reduce the need for medication.

Evidence: Well-established
Nasal saline irrigation

Helps clear allergens from nasal passages and reduce symptoms.

Evidence: Well-established
Immunotherapy

Allergy shots or sublingual tablets can provide long-term relief.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, consult your doctor before vaccination if you are unwell.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription in case of customs checks. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing times gradually to maintain consistent intervals. Keep it in your carry-on luggage to avoid temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old woman with seasonal allergic rhinitis
She started taking this medicine as prescribed for her sneezing and runny nose. Within a few days, her symptoms improved significantly. She experienced mild drowsiness initially, which subsided after a week. She advises taking it at bedtime to minimize daytime sedation.
💡 Lesson: Taking the medicine at bedtime can help manage drowsiness during the day.
👤 A 5-year-old boy with chronic urticaria
His parents noticed that his hives and itching reduced considerably after starting this medicine. They appreciated the syrup form as it was easy to administer. They were advised to avoid giving it with other sedating medicines.
💡 Lesson: Liquid formulations are convenient for children, but caregivers must monitor for sedation.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 1-2 hours after taking a dose.

Q: Can I take it with other allergy medicines?

A: Consult your doctor before combining with other antihistamines, as additive effects may occur.

Q: Is it safe for children?

A: It is safe for children above 6 months when prescribed by a doctor. Dosage depends on age.

Q: What are the side effects?

A: Common side effects include drowsiness, dry mouth, and headache. Serious side effects are rare.

Q: Can I drink alcohol while taking it?

A: Avoid alcohol as it can increase drowsiness and impair your ability to drive or operate machinery.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for airyfen 1mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure allergies permanently.
    Fact: It only controls symptoms; it does not cure allergies.
  • Myth: It is safe to drive after taking this medicine.
    Fact: It may cause drowsiness; avoid driving until you know how it affects you.
  • Myth: It can be used for acute asthma attacks.
    Fact: It is not for acute asthma attacks; use a rescue inhaler instead.

🔄 Alternative Options

Generic Alternatives

  • Ketotifen syrup

Brand Alternatives

  • Zaditen
  • Ketotifen
  • Asthafen

📊 Comparison with Similar Medicines

[{"medicine":"Ketotifen","class":"Antihistamine and mast cell stabilizer","sedation":"Moderate to high","duration":"12-24 hours"},{"medicine":"Cetirizine","class":"Antihistamine","sedation":"Low to moderate","duration":"24 hours"},{"medicine":"Loratadine","class":"Antihistamine","sedation":"Low","duration":"24 hours"}]

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