Almefkem 500mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe allergic reaction with rash and itching
If experiencing severe symptoms, call emergency services immediately.
What is almefkem 500mg tablet used for?
This medicine contains Mefenamic Acid 500mg, an NSAID used to relieve mild to moderate pain, inflammation, and fever. It works by blocking prostaglandin production. Take it with food to avoid stomach upset. Do not use for more than 7 days without medical advice.
- Generic Name: Mefenamic Acid
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 almefkem 500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मेफेनामिक एसिड 500 मिलीग्राम युक्त एक नॉन-स्टेरॉयडल एंटी-इंफ्लेमेटरी ड्रग (NSAID) है। इसका उपयोग हल्के से मध्यम दर्द, सूजन और बुखार को कम करने के लिए किया जाता है। यह मासिक धर्म के दर्द, दांत दर्द, सिरदर्द, मांसपेशियों के दर्द और गठिया के दर्द में राहत देती है। यह शरीर में प्रोस्टाग्लैंडिन नामक रसायन को कम करके काम करती है जो दर्द और सूजन का कारण बनते हैं। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। इसे बिना डॉक्टर की सलाह के 7 दिनों से अधिक न लें। गर्भावस्था के दौरान और स्तनपान कराने वाली महिलाओं को इसका उपयोग डॉक्टर की सलाह के बिना नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सीने में जलन, दस्त, कब्ज, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में पेट में तेज दर्द, काला या खूनी मल, खून की उल्टी, एलर्जी की प्रतिक्रिया जैसे चकत्ते, चेहरे या गले में सूजन, सांस लेने में कठिनाई, सीने में दर्द और पेशाब कम आना शामिल हैं। इन लक्षणों को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: इस दवा को भोजन या दूध के साथ लें ताकि पेट में जलन न हो। खाली पेट न लें। इस दवा के साथ शराब न पिएं क्योंकि इससे पेट में खून बहने का खतरा बढ़ सकता है। बिना डॉक्टर की सलाह के 7 दिनों से अधिक इसका सेवन न करें। यदि आपको पेट के अल्सर, गुर्दे की बीमारी, लीवर की बीमारी, हृदय रोग या अस्थमा है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर की सलाह के बिना न लें। बच्चों की पहुंच से दूर रखें।
💊 almefkem 500mg tablet Uses & Benefits
[{"condition":"Menstrual cramps (dysmenorrhea)","description":"Relieves moderate to severe pain associated with menstruation by reducing prostaglandin levels in the uterus.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Reduces pain and inflammation in joints affected by osteoarthritis, improving mobility.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps manage pain and swelling in rheumatoid arthritis as part of a comprehensive treatment plan.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from mild to moderate dental pain following procedures or due to dental conditions.","evidence":"Well-established"},{"condition":"Headache","description":"Effective for tension headaches and mild migraines.","evidence":"Moderate"},{"condition":"Fever","description":"Reduces elevated body temperature by acting on the hypothalamus.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Relieves pain from strains, sprains, and other soft tissue injuries.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Postoperative pain","description":"May be used off-label for short-term management of postoperative pain.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation
Also treats: Menstrual cramps, Osteoarthritis, Rheumatoid arthritis, Dental pain, Headache, Fever
📋 Drug Information
| Generic Name(s) | Mefenamic Acid |
| Brand Name | Almefkem 250 DT Tablet |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (fenamates) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by reversibly inhibiting the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. This inhibition prevents the conversion of arachidonic acid into prostaglandin H2, which is a precursor for various prostaglandins and thromboxanes. Prostaglandins are responsible for mediating pain, inflammation, and fever. By reducing their production, this medicine provides analgesic, anti-inflammatory, and antipyretic effects. Additionally, it may inhibit leukotriene synthesis and stabilize lysosomal membranes, contributing to its anti-inflammatory action.
Mechanism Steps
💡 How to Take almefkem 500mg tablet
Strength: 500 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 250 mg to 500 mg taken three times a day with food, as needed for pain and inflammation. The maximum daily dose is 1500 mg. For menstrual cramps, the dose may be started at the first sign of cramps. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not take for more than 7 days without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney impairment. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | 1500 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of almefkem 500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Warfarin
- Aspirin
- Other NSAIDs
- Corticosteroids
- Lithium
- Methotrexate
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Beta-blockers
- SSRIs
- Cyclosporine
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of stomach bleeding, ulcers, and liver damage. It may also worsen drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to mefenamic acid or other NSAIDs","History of asthma, urticaria, or allergic reaction to aspirin or NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe kidney disease","Severe liver disease","Heart failure","Third trimester of pregnancy","Children under 14 years of age (unless directed by a doctor)","Use before or after coronary artery bypass graft (CABG) surgery"]
⚠️ Warnings & Precautions
["Take with food or milk to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose or duration.","Use with caution in the elderly due to increased risk of side effects.","Inform your doctor if you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma.","Do not use if you are pregnant, especially in the third trimester, without consulting your doctor.","May cause drowsiness or dizziness; avoid driving or operating machinery until you know how it affects you.","Long-term use may increase the risk of cardiovascular events and kidney problems.","Do not share this medicine with others."]
🤱 Lactation Safety
Mefenamic acid is excreted in breast milk in small amounts. It is generally considered safe for short-term use during breastfeeding, but consult your doctor before use.
💊 Overdose Management
Overdose of this medicine may cause symptoms such as severe nausea, vomiting, stomach pain, drowsiness, ringing in the ears, and in severe cases, seizures, kidney failure, or coma. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be administered if the patient presents early. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine with food or milk to reduce stomach upset. Do not take it on an empty stomach. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not take this medicine for more than 7 days without consulting your doctor. If you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma, inform your doctor before taking this medicine. Do not use this medicine if you are pregnant, especially in the last three months, or if you are breastfeeding without medical advice. Keep out of reach of children. Store at room temperature away from moisture and heat. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if prescribed by your doctor. It may increase the risk of bleeding and interfere with wound healing. Inform your surgeon about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase the risk of bleeding. Your dentist may advise you to stop it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you can continue with your regular exercise routine, but avoid strenuous activities that may cause injury or worsen pain. Listen to your body and rest if you feel dizzy or drowsy.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take breaks and stay hydrated.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe stomach pain, black or bloody stools, signs of an allergic reaction, or if your pain persists beyond 7 days. Do not stop abruptly if you are on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver damage, and cardiovascular events such as heart attack and stroke. Regular monitoring of kidney and liver function, blood counts, and blood pressure is recommended. Use the lowest effective dose for the shortest duration possible.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedApplying heat or cold packs can help reduce localized pain and inflammation.
Evidence: ModerateMay provide pain relief for some individuals with chronic pain.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from moisture and direct sunlight. If crossing time zones, adjust your dosing schedule accordingly, but do not take a double dose. Check customs regulations for carrying prescription medicines in your destination country. Always keep it in your carry-on luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it with food.
A: No, it should be taken with food or milk to reduce the risk of stomach upset and bleeding.
A: It is generally avoided during the third trimester. Consult your doctor before use if you are pregnant or planning to become pregnant.
A: Do not take it for more than 7 days without consulting your doctor.
A: Do not take it with other NSAIDs unless prescribed by your doctor, as it increases the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for almefkem 500mg tablet
View AllAlternative brands with exact same active ingredient:
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mefalth 500mg tabletOrchid Chemicals & Pharmaceuticals Ltd ₹18.27 18.7% CHEAPER
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osra 500mg tabletBennet Pharmaceuticals Limited ₹20.00 11% CHEAPER
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mefrin 500mg tabletRhine Biogenics Pvt Ltd ₹20.63 8.1% CHEAPER
-
mefanex 500mg tabletLividus Pharmaceuticals Pvt Ltd ₹22.97 2.3% COSTLIER
-
mefalgin 500mg tabletAnthus Pharmaceuticals Pvt Ltd ₹23.67 5.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Almefkem 500mg is safe to take for any type of pain without a prescription.
Fact: This medicine is a prescription NSAID and should only be taken as directed by a doctor. It is not suitable for all types of pain and can cause serious side effects if misused. - Myth: You can take Almefkem 500mg on an empty stomach.
Fact: Taking this medicine on an empty stomach increases the risk of stomach upset and bleeding. Always take it with food or milk. - Myth: Almefkem 500mg is safe to use during pregnancy.
Fact: NSAIDs like mefenamic acid are generally avoided during the third trimester of pregnancy due to risk of complications. Consult your doctor before use. - Myth: Almefkem 500mg can be taken long-term for chronic pain.
Fact: Long-term use of this medicine increases the risk of kidney, liver, and cardiovascular problems. It should be used for the shortest duration possible under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Mefenamic Acid 500mg Tablet
Brand Alternatives
- Almefkem 500mg Tablet