acolate m kid syrup orange - Levocetirizine (2.5mg/5ml) + Montelukast (4mg/5ml) medicine

Allercet-M Syrup: Complete Medicine Guide

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🏭 Gujarat Terce Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or wheezing that worsens
  • Severe skin rash, blisters, or peeling skin
  • Yellowing of the eyes or skin, or dark urine
  • Unusual bruising or bleeding
  • Seizures or loss of consciousness
  • Severe abdominal pain or persistent vomiting

If experiencing severe symptoms, call emergency services immediately.

What is acolate m kid syrup orange used for?

This medicine is a combination syrup of levocetirizine and montelukast used to treat allergic rhinitis and mild to moderate asthma. It works by blocking histamine and leukotriene pathways to reduce allergy and asthma symptoms. It is taken once daily, usually in the evening, and may cause drowsiness.

  • Generic Name: Levocetirizine + Montelukast
  • Manufacturer: Gujarat Terce Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 acolate m kid syrup orange के बारे में (Hindi Summary)

उपयोग: यह दवा लेवोसेटिरिज़िन और मॉन्टेलुकास्ट का संयोजन है, जिसका उपयोग एलर्जी राइनाइटिस (नाक की एलर्जी) और हल्के से मध्यम दमा के इलाज के लिए किया जाता है। यह छींक, बहती नाक, नाक में खुजली, और आंखों में पानी आने जैसे लक्षणों को कम करने में मदद करती है। यह सूजन और श्वसन मार्ग की संकीर्णता को भी कम करती है। यह दवा बच्चों और बड़ों दोनों के लिए तरल रूप में उपलब्ध है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, थकान, सूखा मुँह, सिरदर्द और पेट में हल्का दर्द शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। कभी-कभी चक्कर आना, जी मिचलाना या दस्त भी हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई, या त्वचा पर गंभीर दाने दिखें तो तुरंत डॉक्टर से मिलें। बच्चों में चिड़चिड़ापन या व्यवहार में बदलाव हो सकता है, जिसकी जानकारी डॉक्टर को दें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, अपने आप मात्रा न बदलें और न ही बंद करें। यह दवा नींद ला सकती है, इसलिए गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको इसका असर पता न चल जाए। शराब और अन्य नींद लाने वाली दवाओं के साथ इसका सेवन न करें। अगर आपको किडनी या लीवर की बीमारी है, या दौरे पड़ते हैं, तो डॉक्टर को बताएं। अस्थमा के तीव्र दौरे के लिए इस दवा का उपयोग न करें; राहत के लिए इनहेलर का इस्तेमाल करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 acolate m kid syrup orange Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, nasal itching, and congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Mild to moderate allergic asthma","description":"Helps control airway inflammation and reduces the frequency of asthma symptoms when used as add-on therapy.","evidence":"Well-established"},{"condition":"Exercise-induced bronchoconstriction","description":"May reduce narrowing of the airways triggered by physical activity in susceptible patients.","evidence":"Moderate"},{"condition":"Chronic urticaria","description":"Helps reduce itching and hives in some patients with chronic spontaneous urticaria.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Atopic dermatitis","description":"Sometimes used to reduce itching in patients with allergic skin conditions, though not a primary treatment.","evidence":"Limited"},{"condition":"Sleep-related breathing disorders in children","description":"Occasionally prescribed off-label for mild sleep-disordered breathing associated with allergic rhinitis.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Mild to moderate asthma, Exercise-induced bronchoconstriction, Chronic urticaria

📋 Drug Information

Generic Name(s)Levocetirizine + Montelukast
Brand NameAllercet-M Tablet
ManufacturerGujarat Terce Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Leukotriene Receptor Antagonist
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Protect from light and moisture. Do not freeze. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture, or as printed on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine in the evening to minimize daytime drowsiness.
2
Shake the bottle well before measuring each dose.
3
Use the measuring cup or syringe provided; do not use a household spoon.
4
Avoid alcohol and other sedating medicines while taking this syrup.
5
Do not use this medicine as a rescue for acute asthma attacks; keep a fast-acting inhaler available.
6
Report any mood changes, sleep problems, or unusual behavior to your doctor promptly.
7
Consult your doctor if symptoms do not improve within 2 weeks.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Sneezing and runny nose
This medicine is commonly prescribed for allergic rhinitis.
Likely Use
Mild wheezing
This medicine may be used as add-on therapy for mild asthma.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Severe asthma attack
This medicine is not a rescue therapy; seek emergency care.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevocetirizine is rapidly and extensively absorbed after oral administration, with peak plasma concentrations reached in about one hour. Montelukast is also rapidly absorbed after oral administration, with peak plasma concentrations reached in two to four hours. Food does not significantly affect the absorption of either ingredient, but taking the syrup with food may reduce stomach upset.
DistributionLevocetirizine distributes into body tissues, and its plasma protein binding is approximately 90 percent. Montelukast is highly bound to plasma proteins, primarily albumin, and has a small volume of distribution. Both ingredients cross into breast milk in small amounts.
Protein BindingLevocetirizine is about 90 percent bound to plasma proteins. Montelukast is more than 99 percent bound to plasma proteins.
MetabolismLevocetirizine undergoes limited metabolism in the liver, with a small fraction being metabolized by cytochrome P450 enzymes. Montelukast is extensively metabolized in the liver, primarily by CYP2C8 and CYP3A4 enzymes, into inactive metabolites.
Half-LifeThe elimination half-life of levocetirizine is approximately 6 to 8 hours in healthy adults. The elimination half-life of montelukast is approximately 2.7 to 5.5 hours in healthy adults.
ExcretionLevocetirizine is mainly excreted unchanged in the urine, with about 85 percent of a dose recovered in urine and feces. Montelukast is excreted mainly in bile and feces, with only a small amount excreted in urine.
BioavailabilityThe oral bioavailability of levocetirizine is high, approximately 90 percent or more. The oral bioavailability of montelukast is approximately 64 percent when taken without food and may be reduced when taken with a high-fat meal.
Onset of ActionLevocetirizine begins to relieve allergy symptoms within one hour of oral administration. Montelukast may take a few days to produce noticeable improvement in asthma or allergic rhinitis symptoms, with full effects often seen after several days of regular use.
Peak Plasma TimeLevocetirizine reaches peak plasma concentration in about one hour. Montelukast reaches peak plasma concentration in about two to four hours.
Duration of ActionLevocetirizine provides symptom relief for about 24 hours, allowing once-daily dosing. Montelukast provides 24-hour control of leukotriene-mediated symptoms with once-daily dosing.

How It Works

This medicine combines two active ingredients with complementary actions. Levocetirizine is the active enantiomer of cetirizine and works as a selective peripheral histamine H1-receptor antagonist. By blocking H1 receptors, it reduces the immediate allergic response, including sneezing, itching, and increased mucus production. Montelukast is a selective leukotriene receptor antagonist that blocks the cysteinyl leukotriene receptor type 1. This action reduces leukotriene-mediated airway inflammation, bronchoconstriction, mucus secretion, and edema. Together, the two ingredients address both the early histamine-driven phase and the later leukotriene-driven phase of allergic inflammation, which is why the combination is used for allergic rhinitis and asthma.

Mechanism Steps

1
Histamine H1 receptor blockade: Levocetirizine binds to histamine H1 receptors on blood vessels, nerves, and smooth muscle, preventing histamine from triggering allergy symptoms.
2
Reduction of early allergic response: By blocking H1 receptors, levocetirizine reduces sneezing, itching, runny nose, and watery eyes that occur within minutes of allergen exposure.
3
Leukotriene receptor blockade: Montelukast blocks cysteinyl leukotriene receptors, preventing leukotrienes from causing airway narrowing and inflammation.
4
Reduction of late allergic response: Montelukast reduces the later phase of allergic inflammation, including mucus production, swelling, and bronchoconstriction.
5
Combined symptom control: The two ingredients work together to control both immediate and delayed allergic symptoms in the nose and lungs.

💡 How to Take acolate m kid syrup orange

Strength: Each 5 mL of syrup contains levocetirizine 2.5 mg and montelukast 4 mg.

1Shake the bottle well before each use.
2Use the measuring cup or syringe provided with the pack to measure the dose accurately.
3Take the syrup orally, with or without food.
4If it causes stomach upset, take it with a small snack or meal.
5Do not mix the syrup with other liquids unless instructed by your doctor.
6After use, close the bottle tightly and store it as directed.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5 mL to 10 mL of syrup taken orally once daily, preferably in the evening. The exact dose depends on the indication, severity of symptoms, and the patient's kidney and liver function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the sedative effects of levocetirizine. Dose adjustment may be needed based on kidney function. A qualified clinician should determine the appropriate dose.
Renal ImpairmentIn patients with mild renal impairment, no dose adjustment is usually needed. In moderate renal impairment, the dose may need to be reduced. In severe renal impairment, this medicine is contraindicated or should be used with extreme caution. Consult a clinician for individualized dosing.
Hepatic ImpairmentNo dose adjustment is usually needed for mild to moderate hepatic impairment. In severe hepatic impairment, caution is advised and the clinician should determine if dose adjustment is necessary.
Maximum Daily DoseThe maximum recommended daily dose is 10 mL of syrup per day, but this must be confirmed by the prescribing clinician based on the individual patient.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
High-fat meals
Avoid taking at the same time
May reduce montelukast absorption.
Grapefruit juice
Avoid large amounts
May increase montelukast levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of acolate m kid syrup orange

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you. Consult your doctor if drowsiness is persistent or bothersome.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated and consult your doctor if the headache is severe or persistent.
Dry mouth (Common (2-5%))
Sip water regularly. Consult your doctor if dry mouth becomes troublesome.
Fatigue (Common (2-5%))
Get adequate rest. Consult your doctor if fatigue interferes with daily activities.
Abdominal pain (Common (2-5%))
Take the syrup with food to reduce stomach discomfort. Consult your doctor if pain persists.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you notice swelling of the face, lips, tongue, or throat, difficulty breathing, or a widespread rash.
Neuropsychiatric events (Uncommon (0.1-1%))
Report agitation, aggression, hallucinations, depression, or sleep disturbances to your doctor immediately.
Liver injury (Rare (<0.1%))
Seek medical attention if you notice yellowing of the eyes or skin, dark urine, or persistent stomach pain.
Severe skin reactions (Rare (<0.1%))
Stop the medicine and seek immediate medical help if you develop a painful rash, blisters, or peeling skin.

⚠️ Rare Side Effects

Seizures
Seek emergency medical care if a seizure occurs.
Blood disorders such as low platelet count
Report unusual bruising or bleeding to your doctor promptly.
Palpitations
Consult your doctor if you experience a racing or irregular heartbeat.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
CNS depressants Major
Rifampicin Major
Gemfibrozil Moderate
Sedating antihistamines Moderate
Theophylline Minor
Prednisone Minor
Warfarin Moderate
Phenytoin Moderate
Carbamazepine Moderate
Alcohol Major

🚨 Major Interactions

  • CNS depressants (e.g., benzodiazepines, opioids, alcohol)
  • Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin)

⚡ Moderate Interactions

  • CYP2C8 inhibitors (e.g., gemfibrozil)
  • Sedating antihistamines (e.g., diphenhydramine, hydroxyzine)

🍷 Alcohol Interaction

Alcohol can increase the drowsiness and sedation caused by levocetirizine. It is best to avoid alcohol while taking this medicine, especially before driving or operating machinery.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to levocetirizine, montelukast, or any component of the syrup","Severe renal impairment with creatinine clearance less than 10 mL/min (for levocetirizine component)","Children below the age approved by the prescribing clinician for this combination","Acute severe asthma attack requiring rescue therapy"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants while taking this medicine.","Do not use as a rescue medicine for acute asthma attacks.","Use with caution in patients with kidney or liver disease; dose adjustment may be needed.","Neuropsychiatric events have been reported with montelukast; monitor for mood or behavior changes.","Rare serious allergic reactions can occur; seek immediate medical help if they occur.","Do not exceed the prescribed dose.","Keep out of reach of children."]

🤱 Lactation Safety

Both levocetirizine and montelukast are excreted in human breast milk in small amounts. Caution is advised when this medicine is used during breastfeeding. Monitor the infant for drowsiness or irritability, and consult a doctor before use.

💊 Overdose Management

Overdose of this medicine may cause drowsiness, agitation, dizziness, headache, vomiting, or abdominal pain. There is no specific antidote. Treatment is supportive and symptomatic. If a large overdose is suspected, contact a poison control center or seek emergency medical care immediately. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor, and do not change the dose or stop it without medical advice. Because this syrup contains levocetirizine, it may cause drowsiness, so avoid driving, operating heavy machinery, or performing activities that require full alertness until you know how it affects you. Alcohol and other sedating medicines can increase drowsiness and should be avoided. Inform your doctor if you have kidney disease, liver disease, or a history of seizures, as dose adjustment or extra monitoring may be needed. Do not use this medicine to treat a sudden asthma attack; always keep a fast-acting rescue inhaler available if prescribed. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Keep the bottle tightly closed and out of the reach of children. Do not use this medicine after the expiry date printed on the pack. If you miss a dose, follow your doctor's instructions and never double the dose to catch up.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the sedative effects of levocetirizine and may have reduced kidney function. Dose adjustment may be necessary. Monitor for drowsiness, confusion, and falls.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. The safety of this combination during pregnancy is not fully established, and your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with anesthetic agents and increase sedation. Your doctor may advise you to stop it temporarily before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental problems. Maintain good oral hygiene and stay hydrated.

💚 Lifestyle Tips for Better Results

🏃
Identify and avoid allergens such as dust, pollen, and pet dander.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Maintain a healthy weight to reduce asthma symptoms.
💧
Practice regular breathing exercises.
🧘
Get adequate sleep to support immune function.
🌞
Stay hydrated to keep airways moist.

🏋️ Exercise Considerations

Exercise is generally safe, but if you have exercise-induced bronchoconstriction, take your rescue inhaler as prescribed before exercising. Avoid strenuous activity in cold, dry air or high pollen environments. Stop and seek medical help if you experience chest tightness or severe breathlessness.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Eat plenty of fruits and vegetables rich in antioxidants.
Reduce intake of processed and high-fat foods.
Stay well hydrated.
Avoid known food allergens.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is best to take it in the evening and avoid driving until you know how it affects you. Most people can continue their daily activities with caution.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects such as severe allergic reactions, mood changes, or liver problems, stop the medicine and seek immediate medical advice. Your doctor will determine the appropriate duration of treatment.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well tolerated for approved indications. However, montelukast has been associated with rare neuropsychiatric events, and levocetirizine may cause persistent drowsiness in some patients. Regular monitoring of symptoms, kidney function, and mood changes is advised. Do not use for longer than prescribed without medical review.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Reducing exposure to allergens can decrease the need for medication.

Evidence: Well-established
Nasal saline irrigation

Can help relieve nasal congestion and rinse away allergens.

Evidence: Moderate
Immunotherapy

Allergy shots or sublingual tablets can provide long-term relief for allergic rhinitis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are scheduled for allergy testing, inform your doctor, as antihistamines may interfere with skin test results. Live vaccines should be given according to the recommended schedule.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, continue with your regular once-daily schedule, but consult your doctor if you need to adjust the timing. Check customs regulations for carrying prescription medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 7-year-old child with seasonal allergic rhinitis
The child had frequent sneezing, runny nose, and itchy eyes every spring. The doctor prescribed this medicine once daily in the evening. After a week, the symptoms reduced significantly, and the child could play outdoors again. The parents were advised to give the syrup with a small snack to prevent stomach upset.
💡 Lesson: Regular evening dosing and taking with food improves tolerability and symptom control in children.
👤 A 35-year-old adult with mild asthma and allergic rhinitis
The patient experienced wheezing and nasal congestion during exercise. The doctor added this medicine to the existing inhaler therapy. After two weeks, the frequency of wheezing episodes decreased, and nasal symptoms improved. The patient was advised to avoid alcohol and to report any mood changes.
💡 Lesson: Combination therapy can improve both nasal and lung symptoms, but monitoring for neuropsychiatric effects is important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Levocetirizine starts working within one hour, while montelukast may take a few days to show full effect. Symptom improvement is usually seen within a week.

Q: Can I take it at night?

A: Yes, taking it in the evening is often recommended to reduce daytime drowsiness.

Q: Is it safe for children?

A: It may be prescribed for children, but the dose must be determined by a pediatrician. Do not self-administer to children.

Q: Can I stop it suddenly?

A: Do not stop without consulting your doctor, as symptoms may return. Your doctor will advise on the duration of treatment.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for acolate m kid syrup orange

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used as a rescue inhaler for asthma attacks.
    Fact: This medicine is not a rescue medicine. It is used for long-term control, and acute attacks require a fast-acting bronchodilator.
  • Myth: It is safe to take extra doses if symptoms are severe.
    Fact: Taking more than the prescribed dose can increase side effects and does not provide extra benefit. Always follow the prescribed dose.
  • Myth: It is a habit-forming medicine.
    Fact: This medicine is not habit-forming. It does not cause dependence when used as prescribed.

🔄 Alternative Options

Generic Alternatives

  • Levocetirizine + Montelukast oral syrup (generic)

Brand Alternatives

  • Allercet-M Syrup

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Levocetirizine + Montelukast","route":"Oral","primary_use":"Allergic rhinitis and asthma"},{"medicine":"Montelukast + Fexofenadine","composition":"Montelukast + Fexofenadine","route":"Oral","primary_use":"Allergic rhinitis"},{"medicine":"Levocetirizine alone","composition":"Levocetirizine","route":"Oral","primary_use":"Allergic rhinitis and urticaria"}]

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