Alcipro TN 500 mg/600 mg Tablet - Uses, Price, Side Effects
What is alcipro tn 500 mg/600 mg tablet used for?
Alcipro TN 500 mg/600 mg Tablet is a combination of Ciprofloxacin (a fluoroquinolone antibiotic) and Tinidazole (an antiprotozoal agent). It is used to treat gastrointestinal infections such as diarrhea and dysentery caused by bacteria and parasites. Ciprofloxacin stops bacterial growth, while Tinidazole kills protozoa. It is manufactured by Alkem Laboratories.
- Generic Name: Ciprofloxacin + Tinidazole
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ alcipro tn 500 mg/600 mg tablet Uses & Benefits
Infectious diarrhea, dysentery, intra-abdominal infections, gynecologic infections, and mixed infections caused by susceptible bacteria and protozoa.
Off-label uses: Prophylaxis in travelers' diarrhea, treatment of Helicobacter pylori (with other agents).
๐ Drug Information
| Generic Name(s) | Ciprofloxacin + Tinidazole |
| Brand Name | Alcipro TN 500 mg/600 mg Tablet |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibiotic + Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV; Tinidazole disrupts DNA structure in protozoa and anaerobic bacteria.
Mechanism Steps
๐ก How to Take alcipro tn 500 mg/600 mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of alcipro tn 500 mg/600 mg tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Metallic taste
- Vomiting
๐จ Serious Side Effects
- Tendon rupture
- Peripheral neuropathy
- CNS effects (seizures, confusion)
- QT prolongation
- Clostridioides difficile colitis
- Severe hypersensitivity
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Stevens-Johnson syndrome
- Hepatotoxicity
- Nephritis
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Theophylline | Moderate | Increased theophylline levels |
| Antacids | Moderate | Reduced ciprofloxacin absorption |
| Alcohol | Moderate | Increased risk of disulfiram-like reaction |
๐จ Major Interactions
- Warfarin
- Theophylline
- Tizanidine
- NSAIDs
- Oral hypoglycemics
โก Moderate Interactions
- Cyclosporine
- Methotrexate
- Phenytoin
- Probenecid
- Ropinirole
โน๏ธ Minor Interactions
- Caffeine
- Duloxetine
- Metformin
- Omeprazole
๐ฝ๏ธ Food Interactions
Avoid dairy products, calcium-fortified juices, and antacids within 2 hours of ciprofloxacin; Tinidazole may be taken with food to reduce GI upset.
๐ท Alcohol Interaction
Avoid alcohol during and for 3 days after tinidazole due to disulfiram-like reaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to quinolones or nitroimidazoles; history of tendon disorders with quinolones; pregnancy (first trimester for tinidazole); lactation; children <18 years (for ciprofloxacin).
๐ Monitoring Parameters
Renal function, liver function, blood glucose, signs of tendonitis, CNS effects, and QT interval.
๐คฑ Lactation Safety
Ciprofloxacin: Excreted in milk, avoid; Tinidazole: Excreted in milk, avoid.
๐ Overdose Management
Supportive care; monitor ECG, renal function; dialysis may help remove ciprofloxacin.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.