azofen t 200 mg/1 mg tablet - Theophylline (200mg) + Ketotifen (1mg) medicine

Azofen T 200 mg/1 mg Tablet - Uses, Price, Side Effects

4.6 (14 reviews)
๐Ÿญ Lark Laboratories Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is azofen t 200 mg/1 mg tablet used for?

Azofen T 200 mg/1 mg Tablet is a combination of Theophylline (a bronchodilator) and Ketotifen (a mast cell stabilizer) used to prevent and treat asthma and COPD. It works by relaxing airway muscles and reducing allergic inflammation, helping to improve breathing and prevent asthma attacks.

  • Generic Name: Theophylline + Ketotifen
  • Manufacturer: Lark Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š azofen t 200 mg/1 mg tablet Uses & Benefits

Bronchial asthma, chronic obstructive pulmonary disease (COPD), allergic rhinitis.

Off-label uses: Urticaria, atopic dermatitis, anaphylaxis prophylaxis.

๐Ÿ“‹ Drug Information

Generic Name(s)Theophylline + Ketotifen
Brand NameAzofen T 200 mg/1 mg Tablet
ManufacturerLark Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassRespiratory
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTheophylline is well absorbed orally; Ketotifen is well absorbed orally.
DistributionTheophylline distributes into body tissues and crosses placenta; Ketotifen distributes widely.
Protein BindingTheophylline: 40% protein bound; Ketotifen: 75% protein bound.
MetabolismTheophylline: Hepatic via CYP1A2; Ketotifen: Hepatic.
Half-LifeTheophylline: 3-8 hours (adults); Ketotifen: 18-22 hours.
ExcretionTheophylline: Renal (10% unchanged); Ketotifen: Renal and fecal.
BioavailabilityTheophylline: 96%; Ketotifen: 50-60%.
Onset of ActionTheophylline: 30-60 minutes; Ketotifen: 2-4 hours.
Peak Plasma TimeTheophylline: 1-2 hours; Ketotifen: 2-4 hours.
Duration of ActionTheophylline: 6-8 hours; Ketotifen: 12-24 hours.

How It Works

Theophylline: Bronchodilator via phosphodiesterase inhibition and adenosine antagonism; Ketotifen: Mast cell stabilizer and antihistamine.

Mechanism Steps

1Theophylline inhibits phosphodiesterase, increasing cAMP levels.
2Theophylline antagonizes adenosine receptors, reducing bronchoconstriction.
3Ketotifen stabilizes mast cells, preventing degranulation and release of histamine and other mediators.

๐Ÿ’ก How to Take azofen t 200 mg/1 mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of azofen t 200 mg/1 mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Headache
  • Insomnia
  • Drowsiness
  • Dry mouth

๐Ÿšจ Serious Side Effects

  • Seizures
  • Arrhythmias
  • Hypotension
  • Severe allergic reactions

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Rhabdomyolysis
  • Hyperglycemia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Cimetidine Major Increased theophylline toxicity
Ciprofloxacin Major Increased theophylline levels
Erythromycin Major Increased theophylline levels
Fluvoxamine Major Increased theophylline levels
Verapamil Major Increased theophylline levels
Phenytoin Moderate Decreased theophylline levels
Carbamazepine Moderate Decreased theophylline levels
Rifampin Moderate Decreased theophylline levels
Smoking Moderate Increased theophylline clearance
Lithium Minor Increased lithium excretion
Benzodiazepines Minor Antagonism of sedative effects

๐Ÿšจ Major Interactions

  • Cimetidine
  • Ciprofloxacin
  • Erythromycin
  • Fluvoxamine
  • Verapamil

โšก Moderate Interactions

  • Phenytoin
  • Carbamazepine
  • Rifampin
  • Smoking

โ„น๏ธ Minor Interactions

  • Lithium
  • Benzodiazepines

๐Ÿฝ๏ธ Food Interactions

Caffeine-containing foods may increase theophylline levels; high-fat meals may delay absorption.

๐Ÿท Alcohol Interaction

Alcohol may increase theophylline clearance.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Moderate
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to theophylline or ketotifen, active peptic ulcer, seizure disorders (unless controlled).

๐Ÿ“Š Monitoring Parameters

Serum theophylline levels (therapeutic range 10-20 mcg/mL), heart rate, respiratory rate, CNS effects.

๐Ÿคฑ Lactation Safety

Theophylline and Ketotifen are excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Induce emesis or gastric lavage; administer activated charcoal; monitor serum theophylline levels; treat seizures with diazepam; treat arrhythmias with lidocaine.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

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