aggramed 5mg infusion - Uses, Price, Side Effects & Substitutes
What is aggramed 5mg infusion used for?
Aggribloc (Tirofiban) is used to treat Acute coronary syndrome (unstable angina/non-ST-elevation MI) in patients undergoing percutaneous coronary intervention (PCI).. It contains Tirofiban (5mg), which Reversibly inhibits the binding of fibrinogen to the glycoprotein IIb/IIIa recep. Always consult your doctor before use. Take as prescribed.
- Generic Name: Tirofiban
- Manufacturer: Zydus Cadila
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 aggramed 5mg infusion के बारे में संक्षिप्त जानकारी (Hindi Summary)
aggramed 5mg infusion का उपयोग मुख्य रूप से blood related और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Tirofiban (5mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Tirofiban |
|---|---|
| Brand Name | Aggribloc |
| Manufacturer | Zydus Cadila |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Glycoprotein IIb/IIIa inhibitors |
| Route of Administration | Intravenous infusion. |
| Storage | Store at 20-25°C (68-77°F); protect from light; do not freeze. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take aggramed 5mg infusion?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 20-25°C (68-77°F); protect from light; do not freeze.
⚙️ How aggramed 5mg infusion Works
Reversibly inhibits the binding of fibrinogen to the glycoprotein IIb/IIIa receptor on platelets, preventing platelet aggregation.
💊 aggramed 5mg infusion Uses in Hindi (Ke Fayde), Benefits & Indications
Acute coronary syndrome (unstable angina/non-ST-elevation MI) in patients undergoing percutaneous coronary intervention (PCI).
Off-label uses: Adjunctive therapy in high-risk PCI, acute STEMI (limited data).
⚠️ What are the side effects of aggramed 5mg infusion?
✅ Common Side Effects
- Bleeding (minor, e.g., ecchymosis, epistaxis)
- Nausea
- Headache
- Hypotension
🚨 Serious Side Effects
- Major bleeding (intracranial, retroperitoneal, GI)
- Thrombocytopenia
- Anaphylaxis
⚠️ Rare Side Effects
- Acute profound thrombocytopenia
- Hemorrhagic stroke
- Pulmonary hemorrhage
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Heparin | Major | Increased bleeding risk |
| Aspirin | Major | Increased bleeding risk |
| Clopidogrel | Major | Increased bleeding risk |
| NSAIDs | Major | Increased bleeding risk |
| Thrombolytics | Major | Increased bleeding risk |
| Abciximab | Moderate | Additive antiplatelet effect |
| Eptifibatide | Moderate | Additive antiplatelet effect |
| Cilostazol | Moderate | Increased bleeding risk |
| Dipyridamole | Moderate | Increased bleeding risk |
| SSRIs | Moderate | Increased bleeding risk |
| Ginkgo biloba | Minor | Possible increased bleeding risk |
| Garlic | Minor | Possible increased bleeding risk |
| Fish oil | Minor | Possible increased bleeding risk |
| Vitamin E | Minor | Possible increased bleeding risk |
🚨 Major Interactions
- Warfarin
- Heparin
- Aspirin
- Clopidogrel
- NSAIDs
- Thrombolytics
⚡ Moderate Interactions
- Abciximab
- Eptifibatide
- Cilostazol
- Dipyridamole
- SSRIs
ℹ️ Minor Interactions
- Herbal supplements (e.g., ginkgo, garlic)
- Fish oil
- Vitamin E
🍽️ Food Interactions
No significant food interactions.
🍷 Alcohol Interaction
May increase bleeding risk; avoid excessive alcohol consumption.
🛡️ Safety & Warnings
🚫 Contraindications
Active bleeding, history of intracranial hemorrhage, severe hypertension, major surgery within 30 days, thrombocytopenia, hypersensitivity to tirofiban.
📊 Monitoring Parameters
Platelet count, bleeding time, signs of bleeding, hemoglobin/hematocrit, renal function.
🤱 Lactation Safety
Unknown if excreted in human milk; caution advised.
💊 Overdose Management
Discontinue infusion; monitor for bleeding; platelet transfusion may be considered.
⏰ Missed Dose
Not applicable; continuous infusion; if infusion interrupted, restart as soon as possible.
🛑 Myths vs. Facts about aggramed 5mg infusion
- Myth: Generic substitutes of aggramed 5mg infusion are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Tirofiban (5mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of aggramed 5mg infusion can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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