adom 30 mg/20 mg tablet sr - Uses, Price, Side Effects & Substitutes
What is adom 30 mg/20 mg tablet sr used for?
Aciloc RD 20 Tablet (Domperidone + Omeprazole) is used to treat GASTRO INTESTINAL. It contains Domperidone (30mg) + Omeprazole (20mg), which Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal . Always consult your doctor before use. Take as prescribed.
- Generic Name: Domperidone + Omeprazole
- Manufacturer: Tablets India Limited
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ adom 30 mg/20 mg tablet sr Uses & Benefits
Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, peptic ulcer disease.
Off-label uses: Nausea and vomiting of various etiologies, migraine-associated gastroparesis.
๐ Drug Information
| Generic Name(s) | Domperidone + Omeprazole |
| Brand Name | Aciloc RD 20 Tablet |
| Manufacturer | Tablets India Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal motility; Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in parietal cells.
Mechanism Steps
๐ก How to Take adom 30 mg/20 mg tablet sr
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of adom 30 mg/20 mg tablet sr
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Flatulence
- Dry mouth
๐จ Serious Side Effects
- QT prolongation
- Torsades de pointes
- Extrapyramidal symptoms
- Gynecomastia
- Hyperprolactinemia
- Interstitial nephritis
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Anaphylaxis
- Agranulocytosis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased risk of QT prolongation |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Sucralfate | Minor | Reduced absorption of omeprazole |
๐จ Major Interactions
- Ketoconazole
- Itraconazole
- Voriconazole
- Clarithromycin
- Erythromycin
- Ritonavir
- Saquinavir
- Telithromycin
- Nefazodone
- Cobicistat
โก Moderate Interactions
- Warfarin
- Cilostazol
- Methotrexate
- Tacrolimus
- Fluconazole
- Cimetidine
- Digoxin
- Iron salts
- Mycophenolate mofetil
โน๏ธ Minor Interactions
- Sucralfate
- Antacids
- Theophylline
- Caffeine
๐ฝ๏ธ Food Interactions
Omeprazole absorption may be delayed by food; Domperidone should be taken before meals.
๐ท Alcohol Interaction
Alcohol may worsen gastrointestinal irritation and reduce drug efficacy.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, gastrointestinal hemorrhage, mechanical obstruction or perforation, prolactinoma, concurrent use with QT-prolonging drugs.
๐ Monitoring Parameters
ECG for QT interval, renal function, liver function, serum electrolytes, signs of extrapyramidal symptoms.
๐คฑ Lactation Safety
Domperidone is excreted in breast milk; omeprazole is likely excreted. Use with caution.
๐ Overdose Management
Supportive care; ECG monitoring for QT prolongation; activated charcoal if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next scheduled dose.