benzil 5 tablet - Benazepril (5mg) medicine

Apriace 5mg Tablet: Complete Medicine Guide

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🏭 Solarium Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category This medicine is not recommended during pregnancy. It can cause harm to the unborn baby, especially in the second and third trimesters. If you are pregnant or planning to become pregnant, talk to your doctor about safer alternatives. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension and diabetic nephropathy.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, tongue, or throat, or difficulty breathing.
  • Severe dizziness or fainting.
  • Chest pain or irregular heartbeat.
  • Decreased urine output or swelling in the legs.
  • Yellowing of the skin or eyes, or dark urine.
  • Severe abdominal pain or persistent vomiting.
  • Unusual bleeding or bruising.

If experiencing severe symptoms, call emergency services immediately.

What is benzil 5 tablet used for?

This medicine is an ACE inhibitor used to treat high blood pressure and protect kidney function in diabetes. It works by relaxing blood vessels. Take it exactly as prescribed, usually once daily. Do not use during pregnancy.

  • Generic Name: Benazepril (5mg)
  • Manufacturer: Solarium Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 benzil 5 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है। यह मधुमेह (डायबिटीज) वाले रोगियों में गुर्दे की रक्षा के लिए भी इस्तेमाल की जा सकती है। यह दवा हृदय पर दबाव कम करती है और स्ट्रोक तथा दिल के दौरे के जोखिम को कम करने में मदद करती है। इसे डॉक्टर के निर्देशानुसार नियमित रूप से लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान, और सूखी खांसी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ, जीभ या गले में सूजन आए, सांस लेने में कठिनाई हो, या बेहोशी महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बदलें और न ही बंद करें। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं और रक्तचाप बहुत कम हो सकता है। पोटेशियम सप्लीमेंट या नमक के विकल्प बिना डॉक्टर की सलाह के न लें। अगर आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं, तो तुरंत डॉक्टर को बताएं। नियमित रूप से रक्तचाप, गुर्दे की कार्यप्रणाली और पोटेशियम की जांच कराते रहें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 benzil 5 tablet Uses & Benefits

[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of strokes, heart attacks, and kidney problems.","evidence":"Well-established"},{"condition":"Diabetic nephropathy","description":"This medicine may be used to protect kidney function in people with diabetes and high blood pressure.","evidence":"Well-established"},{"condition":"Heart failure","description":"This medicine may be used as part of a treatment plan for heart failure to improve symptoms and reduce hospitalizations.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Post-myocardial infarction","description":"Sometimes prescribed after a heart attack to improve survival and reduce further heart events.","evidence":"Limited"},{"condition":"Proteinuria in non-diabetic kidney disease","description":"May be used to reduce protein loss in urine in certain kidney conditions.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Diabetic nephropathy, Heart failure, Post-myocardial infarction

📋 Drug Information

Generic Name(s)Benazepril (5mg)
Brand Namebenzil 5 tablet
ManufacturerSolarium Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin-converting enzyme (ACE) inhibitors
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineACE inhibitors like benazepril are recommended by the World Health Organization as first-line treatment for hypertension in certain patient groups, especially those with diabetes or kidney disease. However, specific recommendations should be verified with current guidelines.
ICMR GuidelineThe Indian Council of Medical Research recommends ACE inhibitors as one of the first-line options for managing hypertension in adults, particularly in patients with diabetes or kidney disease. Always consult your doctor for personalized advice.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Monitor your blood pressure regularly and keep a record to share with your doctor.
3
Avoid potassium supplements and salt substitutes unless approved by your doctor.
4
If you develop a persistent dry cough, inform your doctor; a different medicine may be needed.
5
Stay hydrated, especially in hot weather or during exercise, to avoid low blood pressure.
6
Do not stop this medicine abruptly without consulting your doctor, as it can cause rebound high blood pressure.
7
Inform all healthcare providers that you are taking this medicine, especially before surgery or dental procedures.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
❌
Swelling in legs
This medicine is not a primary treatment for swelling; consult your doctor.
Not Primary
❌
Dry cough
This medicine can cause dry cough as a side effect.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed from the gastrointestinal tract after oral administration. The absorption is not significantly affected by food, so it can be taken with or without meals. However, taking it with food may reduce stomach upset.
DistributionThis medicine is distributed widely throughout the body. It crosses the placenta and is found in breast milk in small amounts. The extent of distribution into specific tissues is not fully established from the available information.
Protein BindingBenazepril and its active metabolite are highly bound to plasma proteins, primarily albumin. The protein binding is approximately 95%.
MetabolismThis medicine is a prodrug, meaning it is inactive until it is converted in the liver to its active form, benazeprilat. This conversion occurs mainly in the liver. The active metabolite is responsible for the blood pressure-lowering effect.
Half-LifeThe elimination half-life of the active metabolite is approximately 10 to 11 hours. The half-life may be prolonged in people with kidney problems.
ExcretionThis medicine and its metabolites are primarily excreted by the kidneys. About 80% of an oral dose is eliminated in the urine, and about 20% in the feces. In people with kidney problems, the excretion may be slower, requiring dose adjustments.
BioavailabilityThe oral bioavailability of this medicine is approximately 37% when taken as a tablet. The active metabolite has a bioavailability of about 27%.
Onset of ActionThe blood pressure-lowering effect begins within 1 hour after taking a dose, but the maximum effect may take several hours. Full therapeutic effect may take 1 to 2 weeks of regular use.
Peak Plasma TimeThe peak plasma concentration of the active metabolite is reached approximately 1 to 2 hours after oral administration.
Duration of ActionThe blood pressure-lowering effect of a single dose lasts for about 24 hours, allowing for once-daily dosing.

How It Works

This medicine works by blocking the action of an enzyme called angiotensin-converting enzyme (ACE). This enzyme is responsible for converting angiotensin I into angiotensin II, a powerful substance that narrows blood vessels and raises blood pressure. By blocking ACE, this medicine reduces the levels of angiotensin II, which causes blood vessels to relax and widen. This lowers blood pressure and reduces the workload on the heart. It also reduces the secretion of aldosterone, a hormone that causes the body to retain salt and water. As a result, the body loses excess salt and water, further lowering blood pressure. In the kidneys, this medicine helps to reduce pressure within the kidney filters, which can protect kidney function over time.

Mechanism Steps

1
Inhibition of ACE: This medicine binds to and inhibits the angiotensin-converting enzyme, preventing the conversion of angiotensin I to angiotensin II.
2
Reduced angiotensin II: Lower levels of angiotensin II lead to relaxation and widening of blood vessels, which lowers blood pressure.
3
Decreased aldosterone: Reduced angiotensin II also decreases aldosterone secretion, causing the kidneys to excrete more sodium and water and retain potassium.
4
Reduced preload and afterload: The combined effects reduce the volume of blood returning to the heart (preload) and the resistance the heart must pump against (afterload), improving heart function.
5
Kidney protection: By lowering pressure inside the kidney filters, this medicine helps protect kidney function, especially in people with diabetes.

💡 How to Take benzil 5 tablet

Strength: 5 mg immediate-release tablet

1Take this medicine by mouth with or without food.
2Swallow the tablet whole with a glass of water.
3Take it at the same time each day to help you remember.
4If it upsets your stomach, take it with a meal.
5Do not crush, chew, or break the tablet unless your doctor tells you to.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual starting dose of this medicine for high blood pressure is 10 mg once daily, but your doctor may start with 5 mg if you are also taking a diuretic or are at risk of low blood pressure. The dose may be increased gradually based on your response, up to a maximum of 40 mg per day. For kidney protection in diabetes, the dose may be 10 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageOlder adults may be more sensitive to the blood pressure-lowering effects of this medicine. Your doctor may start with a lower dose and monitor you closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn people with kidney problems, the dose may need to be reduced. For moderate kidney impairment, the starting dose is often 5 mg once daily. For severe kidney impairment, this medicine is not recommended. Dose must be individualized by a qualified clinician based on renal function.
Hepatic ImpairmentIn people with liver problems, this medicine should be used with caution. The dose may need to be adjusted. Dose must be individualized by a qualified clinician based on hepatic function.
Maximum Daily Dose40 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.
High-potassium foods
Moderate intake
This medicine can raise potassium levels.
Alcohol
Avoid
Increases risk of dizziness and low blood pressure.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with your regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of benzil 5 tablet

✅ Common Side Effects

Dizziness (Common (5-10%))
Get up slowly from sitting or lying position. Avoid driving if you feel dizzy. Consult your doctor if dizziness persists.
Dry cough (Common (5-10%))
This may be due to the medicine. Consult your doctor if it becomes bothersome; a different medicine may be needed.
Headache (Common (5-10%))
Usually resolves on its own. Consult your doctor if it is severe or persistent.
Tiredness (Common (5-10%))
Rest when needed. Consult your doctor if it interferes with daily activities.
Nausea (Uncommon (1-5%))
Take with food to reduce nausea. Consult your doctor if it continues.

🚨 Serious Side Effects

Angioedema (swelling of face, lips, tongue, throat) (Rare (<0.1%))
Seek emergency medical help immediately if you have difficulty breathing or swelling of the face, lips, tongue, or throat.
Severe hypotension (very low blood pressure) (Rare (<0.1%))
Lie down and call your doctor if you feel faint or have very low blood pressure. This is more common if you are dehydrated or taking diuretics.
Kidney impairment (Rare (<0.1%))
Your doctor will monitor kidney function. Report decreased urine output or swelling.
Hyperkalemia (high blood potassium) (Rare (<0.1%))
Your doctor will check potassium levels. Report muscle weakness or irregular heartbeat.
Severe allergic reaction (Very rare (<0.01%))
Seek emergency help for rash, itching, difficulty breathing, or swelling.

⚠️ Rare Side Effects

Neutropenia (low white blood cell count)
Report fever, sore throat, or unusual infections to your doctor.
Liver problems
Report yellowing of skin or eyes, dark urine, or abdominal pain.
Pancreatitis
Seek medical attention for severe abdominal pain.
Pemphigus-like reactions
Report blistering skin rash to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate
NSAIDs Major
Potassium supplements Major
Lithium Major
Diuretics Moderate
Insulin Moderate
Aliskiren Major
Antacids Minor
Capsaicin Minor
Other antihypertensives Moderate

🚨 Major Interactions

  • Potassium supplements or potassium-sparing diuretics
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Lithium
  • Aliskiren

⚡ Moderate Interactions

  • Diuretics (water pills)
  • Other blood pressure medicines
  • Insulin and oral antidiabetic drugs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can enhance the blood pressure-lowering effect, leading to dizziness, lightheadedness, and fainting. It may also increase the risk of liver problems.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","History of angioedema (swelling of face, lips, throat) related to ACE inhibitors","Severe kidney problems","Bilateral renal artery stenosis","Hypersensitivity to benazepril or any ACE inhibitor","Use with aliskiren in patients with diabetes"]

⚠️ Warnings & Precautions

["This medicine can cause a dry cough. If it becomes bothersome, consult your doctor.","It can cause dizziness, especially when standing up. Rise slowly.","Avoid potassium supplements and salt substitutes containing potassium unless prescribed.","Tell your doctor if you have kidney or liver problems.","Do not use during pregnancy. Use effective contraception while taking this medicine.","Avoid alcohol while taking this medicine.","This medicine may cause low blood sugar in people with diabetes. Monitor blood sugar closely.","Seek immediate medical help if you experience swelling of the face, lips, tongue, or throat."]

🤱 Lactation Safety

This medicine passes into breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.

💊 Overdose Management

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe dizziness, fainting, and very low blood pressure. Treatment is supportive and may include intravenous fluids and close monitoring of vital signs.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor, even if you feel well. High blood pressure often has no symptoms, so you may need to take this medicine long-term. Avoid alcohol while taking this medicine, as it can increase dizziness and lower your blood pressure too much. Stand up slowly from a sitting or lying position to avoid dizziness. Tell your doctor if you have kidney problems, liver problems, diabetes, or if you are on a salt-restricted diet. Do not use potassium supplements or salt substitutes containing potassium without your doctor's approval. If you become pregnant while taking this medicine, contact your doctor immediately. Keep all your medical appointments and get your blood pressure, kidney function, and potassium levels checked regularly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Older adults may be more sensitive to the blood pressure-lowering effects of this medicine. They may be at higher risk of dizziness, falls, and kidney problems. Your doctor may start with a lower dose and monitor you closely. Regular monitoring of kidney function and potassium levels is important.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy. If you are planning to become pregnant, talk to your doctor about safer alternatives. Use effective contraception while taking this medicine. If you become pregnant, stop taking this medicine and contact your doctor immediately.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be temporarily stopped before surgery to avoid low blood pressure during the procedure. Follow your doctor's instructions carefully.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may cause dizziness or low blood pressure during the procedure. Your dentist may take precautions. Do not stop taking this medicine without consulting your doctor.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Follow a low-salt diet rich in fruits and vegetables.
😴
Engage in regular physical activity, such as brisk walking, for at least 30 minutes most days.
💧
Limit alcohol intake and avoid smoking.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep to support overall health.

🏋️ Exercise Considerations

This medicine can cause dizziness, especially when you first start taking it or when the dose is increased. Avoid strenuous exercise or heavy lifting until you know how this medicine affects you. Stay hydrated during exercise. If you feel dizzy or faint, stop exercising and rest.

🥗 Diet Recommendations

Reduce salt intake to help lower blood pressure.
Eat a balanced diet rich in fruits, vegetables, and whole grains.
Limit high-potassium foods if your doctor advises.
Avoid alcohol and excessive caffeine.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities once they adjust to the medicine. Inform your employer if your job involves operating machinery or working at heights.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as angioedema, severe dizziness, or kidney problems, contact your doctor immediately. Your doctor may switch you to a different medicine. If you become pregnant, stop taking this medicine and contact your doctor right away.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for controlling blood pressure and protecting kidney function. Regular monitoring of kidney function, potassium levels, and blood pressure is important. In some people, a persistent dry cough may develop, which may require a change in medication. Rarely, long-term use can be associated with kidney impairment or high potassium levels. Your doctor will adjust the dose as needed based on your response and kidney function.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and weight loss can help lower blood pressure and complement medicine.

Evidence: Well-established
Other antihypertensive classes

Calcium channel blockers, diuretics, or angiotensin receptor blockers (ARBs) may be alternatives if ACE inhibitors are not tolerated.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture. If crossing time zones, adjust the timing of your dose gradually, but consult your doctor first. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with newly diagnosed high blood pressure.
He was prescribed this medicine 5 mg once daily. After two weeks, his blood pressure improved, but he developed a dry cough. His doctor switched him to a different class of medicine, and the cough resolved. He now monitors his blood pressure regularly.
💡 Lesson: Dry cough is a common side effect of ACE inhibitors. If it bothers you, consult your doctor for an alternative.
👤 A 60-year-old woman with diabetes and high blood pressure.
She was started on this medicine to protect her kidneys. She took it regularly and her kidney function remained stable. She also monitored her potassium levels as advised. She emphasizes the importance of regular check-ups.
💡 Lesson: This medicine can protect kidney function in diabetes. Regular monitoring of kidney function and potassium is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1 hour, but the full effect may take 1 to 2 weeks of regular use.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.

Q: What should I do if I miss a dose?

A: If you remember within 12 hours, take it. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe during pregnancy?

A: No, this medicine is not safe during pregnancy. It can harm the unborn baby. Consult your doctor for safer alternatives.

Q: Can I stop taking this medicine if my blood pressure is normal?

A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping can cause it to rise again.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for benzil 5 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure high blood pressure.
    Fact: This medicine controls high blood pressure but does not cure it. You may need to take it long-term.
  • Myth: You can stop taking this medicine once your blood pressure is normal.
    Fact: High blood pressure often has no symptoms. Stopping the medicine can cause your blood pressure to rise again. Always consult your doctor before stopping.
  • Myth: This medicine causes kidney damage.
    Fact: This medicine actually protects kidney function in many people, especially those with diabetes. Regular monitoring is important.

🔄 Alternative Options

Generic Alternatives

  • Benazepril 5 mg tablet

Brand Alternatives

  • Lotensin
  • Cibacen
  • Benazepril

📊 Comparison with Similar Medicines

[{"medicine":"Benazepril","class":"ACE inhibitor","usual_dose":"5-40 mg once daily","notes":"Prodrug, converted to active benazeprilat."},{"medicine":"Enalapril","class":"ACE inhibitor","usual_dose":"5-40 mg daily","notes":"Similar efficacy, also a prodrug."},{"medicine":"Lisinopril","class":"ACE inhibitor","usual_dose":"10-40 mg once daily","notes":"Not a prodrug, longer half-life."}]

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