acetine 1000mg injection - Acetylcysteine (1000mg) medicine

Acetine 1000mg Injection - Uses, Price, Side Effects

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๐Ÿญ Health Biotech Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is acetine 1000mg injection used for?

Acetine 1000mg Injection contains Acetylcysteine, a mucolytic and antioxidant. It is primarily used to treat paracetamol overdose by replenishing glutathione levels, and also helps loosen thick mucus in respiratory conditions like COPD and cystic fibrosis. It works by breaking disulfide bonds in mucus and neutralizing free radicals.

  • Generic Name: Acetylcysteine
  • Manufacturer: Health Biotech Limited
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š acetine 1000mg injection Uses & Benefits

Mucolytic in respiratory conditions (COPD, cystic fibrosis, bronchitis), acetaminophen overdose

Off-label uses: Prevention of contrast-induced nephropathy, treatment of pulmonary fibrosis

๐Ÿ“‹ Drug Information

Generic Name(s)Acetylcysteine
Brand NameAcyline Tablet
ManufacturerHealth Biotech Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassAcetylcysteine -Mucolytic
Route of AdministrationOral, intravenous (for overdose), inhalation
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration
DistributionDistributes widely into body tissues and fluids
Protein Binding50-83%
MetabolismHepatic, primarily deacetylation to cysteine
Half-Life5.6 hours (adults), 11 hours (neonates)
ExcretionRenal (primarily as inactive metabolites)
Bioavailability6-10% (oral, due to extensive first-pass metabolism)
Onset of ActionRapid (within 1 hour for mucolytic effect)
Peak Plasma Time1-3 hours
Duration of Action4-6 hours

How It Works

Reduces mucus viscosity by breaking disulfide bonds; also acts as a precursor to glutathione, providing antioxidant effects

Mechanism Steps

1Acetylcysteine is deacetylated to cysteine in the liver
2Cysteine is a precursor for glutathione synthesis
3Glutathione conjugates with reactive metabolites of acetaminophen, preventing hepatotoxicity

๐Ÿ’ก How to Take acetine 1000mg injection

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of acetine 1000mg injection

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Drowsiness

๐Ÿšจ Serious Side Effects

  • Anaphylactoid reaction
  • Bronchospasm
  • Stevens-Johnson syndrome
  • Seizures

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Metabolic acidosis
  • Hypotension

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Nitroglycerin Moderate Enhanced vasodilation and hypotension
Activated charcoal Minor Reduced efficacy of acetylcysteine

๐Ÿšจ Major Interactions

  • Nitroglycerin
  • Carbamazepine

โšก Moderate Interactions

  • Warfarin
  • Chloroquine

โ„น๏ธ Minor Interactions

  • Activated charcoal
  • Tetracyclines

๐Ÿฝ๏ธ Food Interactions

None known

๐Ÿท Alcohol Interaction

May increase risk of hepatotoxicity; avoid concurrent use

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to acetylcysteine, severe asthma (relative), peptic ulcer disease (relative)

๐Ÿ“Š Monitoring Parameters

Liver function tests (in overdose), respiratory status, signs of hypersensitivity

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; considered compatible with breastfeeding

๐Ÿ’Š Overdose Management

Supportive care; monitor for anaphylactoid reactions, seizures, and metabolic acidosis

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose and resume regular schedule

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for acetine 1000mg injection

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Alternative brands with exact same active ingredient (Acetylcysteine (1000mg)):

Medical Note: Always consult your doctor before switching medications.

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