acefate syrup - Sucralfate (1000mg) medicine

acefate syrup - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Assam Chemical & Pharmaceutical Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is acefate syrup used for?

Ancool SF Suspension (Sucralfate) is used to treat GASTRO INTESTINAL. It contains Sucralfate (1000mg), which Forms a protective barrier over ulcer sites by binding to positively charged pro. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Sucralfate
  • Manufacturer: Assam Chemical & Pharmaceutical Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š acefate syrup Uses & Benefits

Duodenal ulcer, gastric ulcer, gastroesophageal reflux disease (GERD), stress ulcer prophylaxis

Off-label uses: Mucositis (oral), radiation proctitis

๐Ÿ“‹ Drug Information

Generic Name(s)Sucralfate
Brand NameAncool SF Suspension
ManufacturerAssam Chemical & Pharmaceutical Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAnti-Ulcerants
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC); protect from freezing
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimally absorbed; less than 5% absorbed from gastrointestinal tract
DistributionNot significantly distributed; acts locally in GI tract
Protein BindingNot applicable (minimal systemic absorption)
MetabolismNot metabolized; acts locally
Half-LifeNot applicable (minimal systemic absorption)
ExcretionPrimarily excreted unchanged in feces
BioavailabilityLess than 5%
Onset of ActionImmediate upon contact with ulcer site
Peak Plasma TimeNot applicable (minimal systemic absorption)
Duration of ActionUp to 6 hours after a dose

How It Works

Forms a protective barrier over ulcer sites by binding to positively charged proteins in the exudate

Mechanism Steps

1Sucralfate dissociates in gastric acid to form a viscous, sticky paste
2The paste binds to positively charged proteins in the exudate at ulcer sites
3Forms a protective barrier that shields the ulcer from acid, pepsin, and bile salts

๐Ÿ’ก How to Take acefate syrup

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of acefate syrup

โœ… Common Side Effects

  • Constipation
  • Dry mouth
  • Nausea
  • Vomiting
  • Diarrhea

๐Ÿšจ Serious Side Effects

  • Bezoar formation
  • Hypersensitivity reactions
  • Aluminum toxicity (in renal impairment)

โš ๏ธ Rare Side Effects

  • Hyperaluminemia
  • Osteomalacia
  • Encephalopathy (in renal failure)

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Reduced absorption of warfarin
Ciprofloxacin Major Reduced absorption of ciprofloxacin
Tetracycline Major Reduced absorption of tetracycline
Digoxin Major Reduced absorption of digoxin
Phenytoin Major Reduced absorption of phenytoin
Antacids Moderate Reduced efficacy of sucralfate; separate doses by 2 hours
Cimetidine Moderate Reduced absorption of cimetidine
Ranitidine Moderate Reduced absorption of ranitidine
Famotidine Moderate Reduced absorption of famotidine
Theophylline Moderate Reduced absorption of theophylline
Ketoconazole Minor Reduced absorption of ketoconazole
Fluoroquinolones Minor Reduced absorption of fluoroquinolones
Thyroid hormones Minor Reduced absorption of thyroid hormones

๐Ÿšจ Major Interactions

  • Warfarin
  • Ciprofloxacin
  • Tetracycline
  • Digoxin
  • Phenytoin

โšก Moderate Interactions

  • Antacids
  • Cimetidine
  • Ranitidine
  • Famotidine
  • Theophylline

โ„น๏ธ Minor Interactions

  • Ketoconazole
  • Fluoroquinolones
  • Thyroid hormones

๐Ÿฝ๏ธ Food Interactions

Food may delay binding; take on empty stomach

๐Ÿท Alcohol Interaction

No significant interaction; but alcohol may worsen ulcer

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to sucralfate

๐Ÿ“Š Monitoring Parameters

Endoscopic healing of ulcers; symptom relief

๐Ÿคฑ Lactation Safety

Likely safe; minimal systemic absorption

๐Ÿ’Š Overdose Management

Gastric lavage; supportive care; minimal toxicity expected

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for acefate syrup

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Alternative brands with exact same active ingredient (Sucralfate (1000mg)):

Medical Note: Always consult your doctor before switching medications.

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