Sucralfate Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain that does not go away
- Difficulty breathing or swelling of the face, lips, or throat
- Confusion, muscle weakness, or seizures (signs of aluminium toxicity)
- Persistent vomiting or inability to keep fluids down
- Yellowing of the skin or eyes (jaundice)
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is Tpcral Suspension used for?
This medicine is an oral suspension containing sucralfate, used to treat and prevent stomach and duodenal ulcers. It works by forming a protective barrier over the ulcer to shield it from acid and pepsin. It is taken on an empty stomach, usually four times a day.
- Generic Name: Sucralfate (1000mg)
- Manufacturer: Ecocare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Tpcral Suspension के बारे में (Hindi Summary)
उपयोग: यह दवा सुक्राल्फेट सस्पेंशन है, जिसका उपयोग पेट और आंतों के अल्सर के इलाज और रोकथाम के लिए किया जाता है। यह पेट की परत पर एक सुरक्षात्मक परत बनाकर अल्सर को एसिड और पेप्सिन से बचाती है। यह गैस्ट्रिटिस, एसिड रिफ्लक्स और पेट की जलन में भी राहत देती है। इसे खाली पेट लेना चाहिए, आमतौर पर दिन में चार बार। यह दवा उन लोगों के लिए नहीं है जिन्हें गुर्दे की गंभीर बीमारी है या जो डायलिसिस पर हैं।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में कब्ज, मुँह सूखना और हल्का पेट दर्द शामिल हैं। कुछ लोगों को मतली, उल्टी, दस्त या पेट भरा हुआ महसूस हो सकता है। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। दुर्लभ मामलों में गुर्दे की बीमारी वाले लोगों में एल्युमीनियम जमा हो सकता है, जिससे भ्रम, मांसपेशियों में कमजोरी या दौरे पड़ सकते हैं। अगर कोई भी दुष्प्रभाव परेशान करे तो डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को कम या ज्यादा न करें। इसे खाली पेट लें, आमतौर पर भोजन से एक घंटा पहले और सोने से पहले। हर बार उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही मापने वाले कप का उपयोग करें। अन्य दवाओं के साथ लेने से पहले कम से कम दो घंटे का अंतराल रखें। एंटासिड को इस दवा से 30 मिनट पहले या बाद में न लें। अगर आपको गुर्दे की बीमारी है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। इसे बच्चों से दूर रखें।
💊 Tpcral Suspension Uses & Benefits
[{"condition":"Duodenal ulcer","description":"This medicine is used to treat active duodenal ulcers and to prevent their recurrence by forming a protective barrier over the ulcer site.","evidence":"Well-established"},{"condition":"Gastric ulcer","description":"It helps heal gastric ulcers by protecting the stomach lining from acid and pepsin.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"This medicine can reduce symptoms of acid reflux by forming a barrier over the irritated esophagus and stomach lining.","evidence":"Moderate"},{"condition":"Stress ulcer prophylaxis","description":"It is used in critically ill patients to prevent stress-related gastrointestinal bleeding.","evidence":"Moderate"},{"condition":"Gastritis","description":"It provides symptomatic relief in acute and chronic gastritis by protecting the inflamed stomach lining.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Mouth ulcers (aphthous ulcers)","description":"Sometimes used as a mouth rinse to relieve pain and promote healing of mouth ulcers.","evidence":"Limited"},{"condition":"Radiation-induced esophagitis","description":"Occasionally prescribed to soothe esophageal irritation caused by radiation therapy.","evidence":"Limited"},{"condition":"Bile reflux gastritis","description":"May be used to protect the stomach lining from bile reflux after surgery.","evidence":"Limited"}]
Primary treatment for: Peptic ulcer disease
Also treats: Gastroesophageal reflux disease (GERD), Gastritis, Stress ulcer prophylaxis, Esophagitis
📋 Drug Information
| Generic Name(s) | Sucralfate (1000mg) |
| Brand Name | Tpcral Suspension |
| Manufacturer | Ecocare |
| Packaging / Form | bottle of 100 ml Suspension (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Do not freeze. Keep the bottle tightly closed when not in use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works locally in the stomach and duodenum. It forms a complex with proteins in the damaged mucosa, creating a protective barrier that shields the ulcer from acid, pepsin, and bile salts. It also binds to pepsin, reducing its activity, and may stimulate the production of prostaglandins, which help protect the stomach lining. Additionally, it can bind to bile acids, reducing their irritating effect on the stomach. This medicine does not significantly reduce stomach acid production, but it helps the ulcer heal by protecting it from further damage.
Mechanism Steps
💡 How to Take Tpcral Suspension
Strength: Sucralfate 1000 mg per 10 mL oral suspension.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 1 gram (10 mL of the 1000 mg/10 mL suspension) taken orally four times a day, on an empty stomach, one hour before meals and at bedtime. For maintenance therapy, the dose may be reduced to 1 gram twice daily. The dose and duration must be individualized by a qualified clinician based on the indication, severity of the condition, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially constipation and aluminium toxicity. Dose should be individualized by a clinician, and kidney function should be monitored regularly. |
| Renal Impairment | In patients with mild to moderate kidney impairment, no dose adjustment is usually needed. However, in severe kidney impairment or dialysis patients, this medicine should be avoided or used with extreme caution due to the risk of aluminium accumulation. Consult a nephrologist for guidance. |
| Hepatic Impairment | No dose adjustment is required for patients with liver impairment, as this medicine is not significantly metabolized by the liver. |
| Maximum Daily Dose | The maximum recommended daily dose is 8 grams (80 mL of the 1000 mg/10 mL suspension) per day, but this should only be used under medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Tpcral Suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ciprofloxacin | Major | |
| Tetracycline | Major | |
| Levothyroxine | Major | |
| Digoxin | Major | |
| Antacids | Moderate | |
| Ketoconazole | Moderate | |
| Phenytoin | Moderate | |
| Warfarin | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
- Tetracycline antibiotics
- Levothyroxine
- Digoxin
⚡ Moderate Interactions
- Antacids
- Ketoconazole
- Phenytoin
🍷 Alcohol Interaction
Alcohol can irritate the stomach lining and worsen ulcers. It is best to avoid alcohol while taking this medicine, as it may reduce the healing effect and increase the risk of stomach bleeding.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to sucralfate or any component of the formulation","Severe kidney impairment or dialysis patients (risk of aluminium accumulation)","Gastrointestinal obstruction or perforation","Patients with a history of bezoar formation"]
⚠️ Warnings & Precautions
["Use with caution in patients with chronic kidney disease; dose adjustment may be needed.","This medicine may interfere with the absorption of other medicines; separate doses by at least 2 hours.","Do not take antacids within 30 minutes before or after this medicine.","In elderly patients, monitor for constipation and aluminium toxicity.","This medicine should not be used for more than 8 weeks without medical review.","If symptoms do not improve after 4 weeks, consult your doctor.","Avoid alcohol and smoking as they can worsen ulcers.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because it is poorly absorbed from the gastrointestinal tract, the amount in breast milk is likely to be very low. However, caution is advised. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose with this medicine is unlikely to cause serious effects because it is poorly absorbed. However, in large amounts, it may cause gastrointestinal discomfort, constipation, or in patients with kidney disease, aluminium toxicity. Treatment is supportive and symptomatic. If overdose is suspected, contact a poison control center or emergency room immediately. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. This medicine works best when taken on an empty stomach, usually one hour before meals and at bedtime, but your doctor may give you different instructions. Shake the suspension well before each use to ensure the medicine is evenly mixed. Use a proper measuring device to get the correct dose. Do not take this medicine within two hours of other medicines, especially antacids, antibiotics, or heart medicines, because it can reduce their absorption. Avoid taking antacids within 30 minutes before or after this medicine. If you have kidney problems, your doctor may need to adjust the dose or monitor you closely. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Keep this medicine out of the reach of children. Store it at room temperature, away from direct sunlight and moisture. Do not use it after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to constipation and aluminium toxicity, especially if they have kidney impairment. Kidney function should be monitored regularly, and the dose should be adjusted by a clinician. Encourage adequate fluid and fiber intake to prevent constipation.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It is classified as Pregnancy Category B, meaning animal studies show no risk, but human studies are lacking. Use only if clearly needed, as directed by your doctor.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used to prevent stress ulcers, especially in critically ill patients. It should be administered under medical supervision. Inform your surgeon if you are taking this medicine before any surgery.
🦷 Dental Procedures
This medicine does not typically interfere with dental procedures. However, inform your dentist if you are taking it, especially if you have a history of ulcers or are on other medications.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience dizziness or fatigue, avoid strenuous activities. Consult your doctor before starting any new exercise routine, especially if you have an active ulcer.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. If affected, avoid driving or operating heavy machinery. Otherwise, it should not significantly impact your daily work or activities. Take it as prescribed to manage your symptoms effectively.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor will decide if and when to stop the medicine based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe for people with normal kidney function. However, it can cause constipation and, rarely, aluminium accumulation in patients with kidney disease. Prolonged use may lead to hypophosphatemia (low phosphate levels) and bone problems. Regular monitoring of kidney function and phosphate levels may be needed if used for more than 8 weeks. Do not use this medicine for longer than prescribed without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Medicines like omeprazole reduce stomach acid production and are often used for ulcers.
Evidence: Well-establishedMedicines like ranitidine reduce acid production and can heal ulcers.
Evidence: Well-establishedDiet changes, stress reduction, and avoiding alcohol and smoking can complement medical therapy.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, consult your doctor if you have any concerns.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container with cap tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Shake well before each use
❌ DON'T
Do not use if the suspension appears discolored or has particles
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Keep enough supply for your entire trip and carry it in your hand luggage to avoid loss.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts forming a protective barrier within 30-60 minutes, but it may take several days to weeks for ulcer symptoms to improve.
A: No, this medicine should be taken on an empty stomach, at least 1 hour before meals, because food reduces its effectiveness.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is generally safe for people with normal kidney function. However, if you have kidney disease, it can accumulate and cause aluminium toxicity. Consult your doctor.
A: Antacids should not be taken within 30 minutes before or after this medicine, as they can reduce its effectiveness.
🤔 Common Patient Concerns
🔄 Substitutes for Tpcral Suspension
View AllAlternative brands with exact same active ingredient:
-
sucrapil suspensionPsychotropics India Ltd ₹31.64 41.8% CHEAPER
-
starlix syrupScoshia Remedy Inc ₹52.50 3.5% CHEAPER
-
sucrid 1000mg oral suspensionEastern Drug ₹52.50 3.5% CHEAPER
-
ralfat syrupUltra Chiron Pharmaceuticals Pvt Ltd ₹54.38 SAME PRICE
-
Sucralcid 1000mg SuspensionRedson Laboratories Pvt Ltd ₹57.50 5.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Sucralfate is an antacid.
Fact: Sucralfate is not an antacid. It does not neutralize stomach acid but forms a protective barrier over ulcers. - Myth: Sucralfate can be taken with food.
Fact: Sucralfate should be taken on an empty stomach because food reduces its ability to bind to the ulcer. - Myth: Sucralfate works immediately.
Fact: Sucralfate starts working within 30-60 minutes, but it may take several days to weeks for ulcer healing. - Myth: Sucralfate is safe for everyone.
Fact: Sucralfate should be avoided in patients with severe kidney disease due to the risk of aluminium toxicity.
🔄 Alternative Options
Generic Alternatives
- Sucralfate oral suspension
Brand Alternatives
- Sucral Suspension