Amohist Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in sputum or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is zeecof expectorant used for?
This medicine is a combination of guaifenesin and bromhexine used to treat productive cough by thinning mucus and making it easier to cough out.
- Generic Name: Guaifenesin (50mg/5ml) + Bromhexine (4mg/5ml)
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 zeecof expectorant के बारे में (Hindi Summary)
उपयोग: यह दवा गुआइफेनेसिन और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग बलगम वाली खांसी के इलाज के लिए किया जाता है। यह बलगम को पतला करके उसे बाहर निकालने में मदद करती है। यह सूखी खांसी के लिए नहीं है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में परेशानी, दस्त, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी प्रतिक्रिया या त्वचा पर गंभीर दाने हो सकते हैं। किसी भी असामान्य लक्षण पर डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। चक्कर आने पर वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 zeecof expectorant Uses & Benefits
[{"condition":"Productive cough with thick mucus","description":"Helps loosen and thin mucus, making it easier to cough out.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Used as supportive therapy to relieve chest congestion and facilitate mucus clearance.","evidence":"Moderate"},{"condition":"Chronic obstructive pulmonary disease (COPD) with mucus hypersecretion","description":"May help in managing thick secretions, but not a primary treatment.","evidence":"Limited"}]
Off-label uses: [{"condition":"Sinusitis with thick nasal discharge","description":"Sometimes used to thin sinus secretions, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Productive cough
Also treats: Acute bronchitis, COPD with mucus hypersecretion
📋 Drug Information
| Generic Name(s) | Guaifenesin (50mg/5ml) + Bromhexine (4mg/5ml) |
| Brand Name | zeecof expectorant |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place, away from direct sunlight. Do not refrigerate. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Guaifenesin increases the volume and reduces the viscosity of bronchial secretions by stimulating gastric reflexes and possibly directly acting on the respiratory tract. Bromhexine increases serous bronchial secretion and breaks down acidic mucopolysaccharide fibers in mucus, reducing its viscosity. Together, they enhance mucociliary clearance and make cough more productive.
Mechanism Steps
💡 How to Take zeecof expectorant
Strength: Each 5 ml contains guaifenesin 50 mg and bromhexine 4 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 5-10 ml every 4-6 hours as needed, not to exceed 60 ml in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to side effects such as dizziness and drowsiness. Use with caution and adjust dose as directed by a clinician. |
| Renal Impairment | Dose adjustment may be needed in patients with kidney disease. Consult a clinician for individualized dosing. |
| Hepatic Impairment | Dose adjustment may be needed in patients with liver disease. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | For adults, the maximum recommended dose is 60 ml in 24 hours. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of zeecof expectorant
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Codeine | Major | |
| Dextromethorphan | Major | |
| MAOIs | Major | |
| Amoxicillin | Moderate | |
| Doxycycline | Moderate | |
| Paracetamol | Minor |
🚨 Major Interactions
- Cough suppressants (e.g., codeine, dextromethorphan)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Antibiotics (e.g., amoxicillin, doxycycline)
- Antitussives (e.g., dextromethorphan)
🍷 Alcohol Interaction
Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to guaifenesin, bromhexine, or any component of the formulation.","Gastric ulcer or duodenal ulcer.","Severe liver disease.","Severe kidney disease.","Children under 2 years of age."]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose.","Avoid using for prolonged periods without medical advice.","Use with caution in patients with asthma or bronchospasm.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Consult a doctor if cough persists for more than 7 days, or is accompanied by fever, rash, or persistent headache.","Do not use in children under 2 years without medical advice."]
🤱 Lactation Safety
It is not known whether guaifenesin and bromhexine pass into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and abdominal pain. In severe cases, it may lead to drowsiness, dizziness, or seizures. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Shake the bottle well before each use and measure with the provided measuring cup or spoon. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Do not take this medicine with other cough and cold products without consulting a doctor, as they may contain overlapping ingredients. If you are pregnant, planning pregnancy, or breastfeeding, inform your doctor before use. Keep out of reach of children. Store in a cool, dry place, away from direct sunlight. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to side effects like dizziness and drowsiness. Use with caution and monitor for falls.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are pregnant, planning pregnancy, or breastfeeding. The safety profile is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, especially if you are taking other medications or have underlying conditions.
🦷 Dental Procedures
No specific precautions. Inform your dentist if you are taking this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you have fever or feel weak. Light activity like walking may be okay if you feel up to it. Consult your doctor before resuming intense exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe to continue desk work.
🛑 When to Stop This Medicine
Stop this medicine and consult your doctor if your cough persists for more than 7 days, or if you experience severe side effects. Do not stop prescribed antibiotics without consulting your doctor.
📅 Long-Term Use Effects
Prolonged use of guaifenesin at high doses has been associated with kidney stones. Bromhexine is generally well tolerated for short-term use. Long-term use should be under medical supervision. Regular monitoring of kidney function may be advised if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve congestion.
Evidence: Well-establishedCan help clear nasal passages and reduce postnasal drip.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, if you have an active infection, consult your doctor about timing of vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, continue dosing as prescribed, but do not exceed the maximum daily dose. Check customs regulations for carrying medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: It may start working within 30 minutes to 1 hour, but noticeable relief may take a few doses.
A: Do not take with other cough suppressants without consulting your doctor, as they may counteract each other.
🤔 Common Patient Concerns
🔄 Substitutes for zeecof expectorant
View AllAlternative brands with exact same active ingredient:
-
ascodex plus syrupGlenmark Pharmaceuticals Ltd ₹31.94 5.4% CHEAPER
-
vizcof ls syrupMinova Life Sciences Pvt Ltd ₹32.81 2.8% CHEAPER
-
Ricof T SyrupRbs Pharmaceutical ₹32.81 2.8% CHEAPER
-
Trustyl X SyrupAbbott ₹37.40 10.8% COSTLIER
-
mucoff syrupShreeji Healthcare Impex ₹38.44 13.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: It is only for productive cough with thick mucus. It is not effective for dry cough. - Myth: It is safe to take this medicine for a long time.
Fact: Prolonged use without medical supervision can be harmful. Use only as directed.
🔄 Alternative Options
Generic Alternatives
- Guaifenesin + Bromhexine syrup (various manufacturers)
Brand Alternatives
- Amohist syrup