Emefast O 4mg/10mg Tablet: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, itching, swelling of face/lips/throat, difficulty breathing.
- Irregular heartbeat, palpitations, or fainting.
- Severe diarrhea with fever or blood.
- Muscle cramps, spasms, or seizures (signs of low magnesium).
- Yellowing of skin or eyes (jaundice).
- Decreased urine output or swelling.
- Severe abdominal pain or blood in vomit/stool.
If experiencing severe symptoms, call emergency services immediately.
What is vozo on 4mg/10mg tablet used for?
This medicine is a combination of Ondansetron (4 mg) and Omeprazole (10 mg) used to treat nausea, vomiting, and acid-related stomach discomfort. It works by blocking nausea signals in the brain and reducing stomach acid production.
- Generic Name: Ondansetron (4mg) + Omeprazole (10mg)
- Manufacturer: Afive Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 vozo on 4mg/10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ओंडान्सेट्रॉन 4 मिलीग्राम और ओमेप्राज़ोल 10 मिलीग्राम का संयोजन है। इसका उपयोग मतली, उल्टी और पेट की अम्लता से जुड़ी समस्याओं के इलाज के लिए किया जाता है। ओंडान्सेट्रॉन मतली और उल्टी को रोकता है, जबकि ओमेप्राज़ोल पेट में एसिड का उत्पादन कम करता है। यह दवा आमतौर पर गैस्ट्राइटिस, एसिड रिफ्लक्स, कीमोथेरेपी या सर्जरी के बाद होने वाली मतली और उल्टी में दी जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, कब्ज, दस्त, थकान, चक्कर आना और पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, अनियमित दिल की धड़कन, गंभीर दस्त, या मांसपेशियों में ऐंठन हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे पानी के साथ पूरा निगलें, चबाएं नहीं। भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन भोजन के साथ लेने से पेट की जलन कम होती है। शराब का सेवन न करें। चक्कर आने पर वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 vozo on 4mg/10mg tablet Uses & Benefits
[{"condition":"Nausea and vomiting with acid dyspepsia","description":"Used to control nausea and vomiting while simultaneously reducing stomach acid in conditions like gastritis or gastroesophageal reflux disease.","evidence":"Well-established for individual components; combination use is common in clinical practice."},{"condition":"Chemotherapy-induced nausea and vomiting (CINV) with acid suppression","description":"Ondansetron prevents chemotherapy-induced nausea, and omeprazole may help prevent acid-related stomach discomfort caused by stress or steroids used during chemotherapy.","evidence":"Ondansetron is well-established for CINV; omeprazole use is supportive."},{"condition":"Post-operative nausea and vomiting (PONV) with acid protection","description":"Ondansetron is effective for PONV, and omeprazole may be added to prevent acid aspiration or stress ulcers in surgical patients.","evidence":"Ondansetron is well-established for PONV; omeprazole use is adjunctive."},{"condition":"Gastroenteritis with vomiting and acidity","description":"Helps reduce vomiting and soothe acid-related stomach irritation during acute gastroenteritis.","evidence":"Symptomatic use; evidence for combination is limited but clinically practiced."}]
Off-label uses: [{"condition":"Hyperemesis gravidarum","description":"Ondansetron is sometimes used off-label for severe nausea and vomiting in pregnancy, but omeprazole is generally avoided unless clearly needed.","evidence":"Limited; use only under specialist care."},{"condition":"Cyclic vomiting syndrome","description":"Ondansetron may be used to abort episodes, and omeprazole may be added for acid suppression.","evidence":"Limited; specialist use."}]
Primary treatment for: Nausea and vomiting with acid-related stomach discomfort
Also treats: Gastroesophageal reflux disease (GERD), Gastritis, Peptic ulcer disease, Chemotherapy-induced nausea and vomiting, Post-operative nausea and vomiting
📋 Drug Information
| Generic Name(s) | Ondansetron (4mg) + Omeprazole (10mg) |
| Brand Name | vozo on 4mg/10mg tablet |
| Manufacturer | Afive Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Ondansetron is a selective 5-HT3 receptor antagonist. It blocks serotonin (5-hydroxytryptamine) at 5-HT3 receptors located on vagal nerve terminals in the gastrointestinal tract and in the chemoreceptor trigger zone of the central nervous system. This blockade prevents the initiation of the vomiting reflex, thereby reducing nausea and vomiting. Omeprazole is a proton pump inhibitor. It is a weak base that accumulates in the acidic environment of the gastric parietal cell canaliculi, where it is converted to its active form. This active form then binds irreversibly to the hydrogen-potassium ATPase (proton pump) enzyme, inhibiting the final step of gastric acid secretion. This results in a profound and long-lasting reduction of both basal and stimulated acid production.
Mechanism Steps
💡 How to Take vozo on 4mg/10mg tablet
Strength: Each tablet contains Ondansetron 4 mg and Omeprazole 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily, or as directed by your doctor. The exact dose and frequency depend on the condition being treated, your age, weight, kidney and liver function, and other medications you are taking. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and confusion. Dose adjustment may be necessary based on kidney and liver function. Consult a doctor for appropriate dosing. |
| Renal Impairment | No specific dose adjustment is typically required for ondansetron in renal impairment. Omeprazole does not require dose adjustment in renal impairment, but use with caution in severe kidney disease. Consult your doctor. |
| Hepatic Impairment | In patients with mild to moderate liver impairment, no dose adjustment is usually needed for ondansetron, but the maximum daily dose should not exceed 8 mg. Omeprazole dose should be reduced in severe liver impairment. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose of ondansetron is generally 16 mg for adults, but for this combination, the maximum recommended dose is one tablet twice daily or as prescribed. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of vozo on 4mg/10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Apomorphine | Major | |
| Amiodarone | Major | |
| Warfarin | Major | |
| Clopidogrel | Major | |
| Methotrexate | Major | |
| Diazepam | Moderate | |
| Phenytoin | Moderate | |
| Ketoconazole | Moderate | |
| Tramadol | Moderate | |
| SSRIs | Moderate |
🚨 Major Interactions
- Apomorphine
- Amiodarone
- Warfarin
- Clopidogrel
- Methotrexate
⚡ Moderate Interactions
- Diazepam
- Phenytoin
- Ketoconazole, itraconazole
- Tramadol
- SSRIs (e.g., fluoxetine, sertraline)
🍷 Alcohol Interaction
Alcohol may increase dizziness, drowsiness, and stomach irritation when taken with this medicine. It is advisable to avoid alcohol during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ondansetron or omeprazole","Concurrent use with apomorphine","Use in patients with phenylketonuria if tablet contains aspartame","Severe liver impairment (for omeprazole, dose adjustment needed)","Congenital long QT syndrome (for ondansetron)"]
⚠️ Warnings & Precautions
["May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol as it may increase drowsiness and stomach irritation.","Use with caution in patients with liver disease; dose adjustment may be needed.","Use with caution in patients with kidney disease.","Long-term use of omeprazole may increase risk of bone fractures, B12 deficiency, and gut infections.","Ondansetron may mask symptoms of intestinal obstruction.","Do not use for longer than prescribed without medical supervision.","Inform your doctor if you have heart rhythm problems or are taking other medications."]
🤱 Lactation Safety
Ondansetron and omeprazole are excreted in breast milk. Consult your doctor before breastfeeding while taking this medicine. Monitoring of the infant for side effects is advised.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, dizziness, fainting, irregular heartbeat, or seizures. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if overdose is recent. Monitor vital signs and ECG.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach upset. Avoid alcohol while taking this medicine as it can worsen dizziness and stomach irritation. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Inform your doctor if you have liver disease, kidney disease, heart rhythm problems, or low magnesium levels. Do not take this medicine for longer than recommended without medical supervision. Keep out of reach of children. Store at room temperature away from moisture and heat. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness, confusion, and electrolyte imbalances. Dose adjustment may be necessary based on kidney and liver function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Ondansetron may be used with caution during pregnancy, but omeprazole should be used only if clearly needed. Discuss the risks and benefits with your healthcare provider.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to prevent nausea and vomiting and to reduce the risk of stress ulcers. Follow your doctor's instructions carefully. Inform your surgeon if you are taking this medicine before any surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, especially if you have a history of acid reflux or are prone to nausea. It may be advisable to take your dose as scheduled to prevent nausea during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy, fatigued, or nauseous. Light activities like walking may be beneficial once symptoms improve. Consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to rest and recover, especially if you are experiencing nausea and vomiting.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Usually, this medicine is prescribed for a short duration, and your doctor will advise when to stop.
📅 Long-Term Use Effects
Long-term use of omeprazole may increase the risk of bone fractures, vitamin B12 deficiency, low magnesium levels, and certain gut infections. Ondansetron is generally not used long-term. Regular monitoring of blood tests and clinical review is recommended if prolonged use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating bland foods and avoiding triggers can help manage nausea and acidity.
Evidence: Well-established for symptom management.Oral rehydration solutions can help maintain electrolyte balance during vomiting.
Evidence: Well-established.May help reduce nausea in some patients.
Evidence: Limited evidence.💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are unwell with nausea and vomiting, it is best to postpone vaccination until you recover. Consult your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Ondansetron starts relieving nausea within 30-60 minutes, while omeprazole begins reducing acid within 1 hour. Full effects may take a few days.
A: It can be taken with or without food, but taking it with food may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: It is advisable to avoid alcohol as it may increase dizziness and stomach irritation.
A: Consult your doctor before taking this medicine during pregnancy. Ondansetron may be used with caution, but omeprazole should be used only if clearly needed.
🤔 Common Patient Concerns
🔄 Substitutes for vozo on 4mg/10mg tablet
View AllAlternative brands with exact same active ingredient:
-
vomer 4mg/10mg tabletLurex Healthcare Pvt Ltd ₹26.78 35.1% CHEAPER
-
diocid o 4mg/10mg tabletIntra Labs India Pvt Ltd ₹45.94 11.4% COSTLIER
-
ompicid o 4mg/10mg tabletIntra Life ₹45.94 11.4% COSTLIER
-
genset o 4mg/10mg tabletCaptab Biotec ₹46.88 13.6% COSTLIER
-
myset-o tabletNovogen Captab ₹46.88 13.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of stomach problems.
Fact: It is specifically for nausea, vomiting, and acid-related discomfort. It does not treat infections or other causes of stomach pain. - Myth: It is safe to take this medicine for as long as you want.
Fact: Long-term use should be under medical supervision due to potential side effects like bone fractures and vitamin deficiencies. - Myth: You can drink alcohol while taking this medicine.
Fact: Alcohol can worsen dizziness and stomach irritation. It is best to avoid alcohol.
🔄 Alternative Options
Generic Alternatives
- Ondansetron + Omeprazole
Brand Alternatives
- Emeset O
- Vomikind O
- Ondem O