voglikem-m 0.2 tablet sr - Metformin (500mg) + Voglibose (0.2mg) medicine

Advog M 0.2 Tablet SR: Complete Medicine Guide

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🏭 Alkem Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for metformin; moderate for Voglibose as add-on therapy.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Rapid breathing or difficulty breathing
  • Severe muscle pain or weakness
  • Extreme fatigue or unusual sleepiness
  • Persistent nausea, vomiting, or stomach pain
  • Signs of hypoglycemia: shakiness, sweating, confusion, blurred vision
  • Yellowing of skin or eyes (jaundice)
  • Decreased urine output or swelling in legs

If experiencing severe symptoms, call emergency services immediately.

What is voglikem-m 0.2 tablet sr used for?

This medicine is a combination of Metformin and Voglibose used to treat type 2 diabetes. It lowers blood sugar by reducing liver glucose production and slowing carbohydrate absorption. Take it with meals as prescribed by your doctor.

  • Generic Name: Metformin (500mg) + Voglibose (0.2mg)
  • Manufacturer: Alkem Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 voglikem-m 0.2 tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। इसमें मेटफॉर्मिन और वोग्लिबोज दो दवाएं होती हैं जो खून में शुगर के स्तर को कम करने में मदद करती हैं। यह दवा खासकर उन लोगों के लिए है जिनका खाने के बाद शुगर बहुत बढ़ जाता है। इसे डॉक्टर की सलाह के अनुसार खाने के साथ लेना चाहिए।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में पेट में गैस, सूजन, दस्त, जी मिचलाना और पेट में असहजता शामिल हैं। ये आमतौर पर कुछ हफ्तों में कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन लैक्टिक एसिडोसिस (तेज सांस लेना, मांसपेशियों में दर्द, अत्यधिक कमजोरी) हो सकता है। अगर ऐसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को हमेशा खाने के साथ लें ताकि पेट की समस्याएं कम हों। खाना न छोड़ें, खासकर अगर आप इंसुलिन या सल्फोनिलयूरिया भी ले रहे हैं। दिन भर पर्याप्त पानी पिएं। शराब का सेवन न करें क्योंकि इससे लैक्टिक एसिडोसिस और शुगर कम होने का खतरा बढ़ सकता है। अपने डॉक्टर की सलाह के बिना दवा बंद या डोज न बदलें। नियमित रूप से ब्लड शुगर की जांच करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 voglikem-m 0.2 tablet sr Uses & Benefits

[{"condition":"Type 2 diabetes mellitus","description":"Used as an adjunct to diet and exercise to improve glycemic control in adults whose blood sugar is not controlled by metformin alone.","evidence":"Well-established"},{"condition":"Postprandial hyperglycemia","description":"Voglibose specifically targets the spike in blood sugar after meals, making this combination useful for patients with high post-meal glucose levels.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Prediabetes","description":"Sometimes prescribed off-label to delay progression to type 2 diabetes in high-risk individuals, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Polycystic ovary syndrome (PCOS)","description":"Metformin component may be used off-label for insulin resistance in PCOS, but the combination with Voglibose is not standard for this indication.","evidence":"Limited"}]

Primary treatment for: Type 2 diabetes mellitus

Also treats: Postprandial hyperglycemia, Insulin resistance

📋 Drug Information

Generic Name(s)Metformin (500mg) + Voglibose (0.2mg)
Brand Namevoglikem-m 0.2 tablet sr
ManufacturerAlkem Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineMetformin is recommended as a first-line oral antidiabetic agent by the World Health Organization for type 2 diabetes. Voglibose is not specifically mentioned in WHO essential medicines list. This combination is used in clinical practice based on individual patient needs.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) guidelines for type 2 diabetes recommend metformin as initial therapy. Alpha-glucosidase inhibitors like Voglibose may be used as add-on therapy for postprandial hyperglycemia. This fixed-dose combination is not specifically addressed in ICMR guidelines.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with meals to reduce gastrointestinal side effects and enhance Voglibose efficacy.
2
Monitor your blood sugar regularly, especially if you are also taking insulin or sulfonylureas.
3
Stay well hydrated to help your kidneys excrete metformin efficiently.
4
Avoid alcohol completely while on this medicine to prevent lactic acidosis.
5
Inform your doctor if you are scheduled for surgery or contrast imaging, as this medicine may need to be temporarily stopped.
6
Report any symptoms of lactic acidosis such as rapid breathing, muscle pain, or extreme fatigue immediately.
7
Do not stop or change the dose without consulting your doctor, even if you feel better.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

High blood sugar after meals
This medicine is commonly prescribed for this.
Likely Use
Frequent urination and thirst
May indicate poorly controlled diabetes; consult your doctor.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMetformin is slowly and incompletely absorbed from the gastrointestinal tract, with bioavailability of about 50-60%. Voglibose is poorly absorbed systemically, with less than 2% of an oral dose reaching the bloodstream, as it acts locally in the gut.
DistributionMetformin is widely distributed to body tissues and fluids, including the liver, kidney, and gastrointestinal tract. It does not bind significantly to plasma proteins. Voglibose has negligible systemic distribution due to its poor absorption.
Protein BindingMetformin is negligibly bound to plasma proteins. Voglibose binding to plasma proteins is not established from the available information.
MetabolismMetformin is not metabolized in the liver and is excreted unchanged in the urine. Voglibose is metabolized to a minor extent in the intestine and liver, but the majority is excreted unchanged in the feces.
Half-LifeThe elimination half-life of metformin is approximately 6.2 hours from plasma and about 17.6 hours from whole blood. The half-life of Voglibose is not established from the available information.
ExcretionMetformin is excreted unchanged in the urine by active tubular secretion and glomerular filtration. Voglibose is primarily excreted in the feces, with a small amount in urine.
BioavailabilityThe absolute bioavailability of metformin is approximately 50-60%. The systemic bioavailability of Voglibose is very low (less than 2%) due to poor absorption.
Onset of ActionThe onset of blood glucose-lowering effect for metformin is within days, but full therapeutic effect may take 1-2 weeks. Voglibose acts within 30-60 minutes after a meal to reduce postprandial glucose.
Peak Plasma TimeMetformin reaches peak plasma concentration in about 2.5 hours after an oral dose. Voglibose peak plasma levels are not established due to poor absorption.
Duration of ActionThe glucose-lowering effect of metformin lasts for about 24 hours with immediate-release formulations. Voglibose effect lasts for about 4-6 hours after a meal.

How It Works

This medicine combines two oral antidiabetic agents with complementary mechanisms. Metformin decreases hepatic glucose production, reduces intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Voglibose is an alpha-glucosidase inhibitor that delays the digestion of carbohydrates in the small intestine, thereby reducing the postprandial rise in blood glucose. Together, they address both fasting and post-meal blood sugar levels.

Mechanism Steps

1
Metformin inhibits hepatic gluconeogenesis: Metformin reduces the production of glucose in the liver by inhibiting mitochondrial respiratory chain complex I, leading to decreased ATP and increased AMP, which activates AMPK and reduces expression of gluconeogenic enzymes.
2
Metformin improves insulin sensitivity: Metformin enhances peripheral glucose uptake in skeletal muscle and adipose tissue by increasing insulin receptor tyrosine kinase activity and GLUT4 translocation.
3
Voglibose inhibits alpha-glucosidase: Voglibose competitively inhibits alpha-glucosidase enzymes in the intestinal brush border, delaying the breakdown of complex carbohydrates into monosaccharides.
4
Reduced postprandial glucose absorption: Because carbohydrates are digested more slowly, glucose enters the bloodstream gradually, preventing sharp post-meal spikes in blood sugar.

💡 How to Take voglikem-m 0.2 tablet sr

Strength: Tablet containing Metformin 500 mg and Voglibose 0.2 mg.

1Take this medicine orally with meals, preferably with the first bite of food.
2Swallow the tablet whole with a glass of water. Do not crush or chew.
3Follow your doctor's prescribed dose and frequency exactly.
4Do not skip meals while taking this medicine.
5If you miss a dose, take it as soon as you remember with a meal, but do not double dose.
6Monitor your blood sugar regularly as advised by your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally two or three times daily with meals, or as directed by your physician. The dose must be individualized by a qualified clinician based on your blood sugar levels, kidney function, and overall health. Do not self-adjust the dose. Regular monitoring of blood glucose and HbA1c is essential to determine the optimal dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially metformin, due to age-related decline in renal function. Dose should be adjusted based on renal function. Regular monitoring of kidney function is recommended.
Renal ImpairmentMetformin is contraindicated in severe renal impairment (eGFR <30 mL/min/1.73 m²). In mild to moderate renal impairment, dose reduction may be necessary. Voglibose dose adjustment in renal impairment is not established. Consult your doctor for individualized dosing.
Hepatic ImpairmentThis medicine should be used with caution in patients with liver disease due to increased risk of lactic acidosis. Dose adjustment may be required. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose of metformin is 2000-2550 mg, and Voglibose is 0.6-0.9 mg, depending on the formulation. However, the exact maximum dose for this fixed-dose combination must be determined by your clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with the first bite of food
Enhances Voglibose effect and reduces stomach upset.
High-fiber foods
Include in diet
Helps control blood sugar levels.
Simple sugars
Limit intake
Voglibose does not prevent absorption of simple sugars.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember with a meal.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of voglikem-m 0.2 tablet sr

✅ Common Side Effects

Flatulence (Common (10-30%))
Usually decreases with continued use. Avoid gas-producing foods and take with meals.
Abdominal bloating (Common (10-20%))
Take with food and stay hydrated. Consult doctor if persistent.
Diarrhea (Common (10-20%))
Stay hydrated. If severe or persistent, contact your doctor.
Nausea (Common (5-10%))
Take with meals. Usually resolves over time.
Metallic taste (Uncommon (1-5%))
Usually temporary. Chewing sugar-free gum may help.

🚨 Serious Side Effects

Lactic acidosis (Rare (<0.1%))
Seek immediate medical attention if you experience rapid breathing, severe muscle pain, extreme weakness, or stomach pain.
Severe hypoglycemia (Rare when used alone, more common with insulin or sulfonylureas)
If you experience shakiness, sweating, confusion, or blurred vision, check your blood sugar and eat fast-acting sugar. Seek medical help if severe.
Vitamin B12 deficiency (Uncommon with long-term use)
Periodic monitoring of vitamin B12 levels is advised. Supplement if deficient.

⚠️ Rare Side Effects

Hepatitis
Report yellowing of skin or eyes, dark urine, or right upper abdominal pain immediately.
Severe allergic reaction
Seek emergency care if you develop rash, swelling of face/lips/throat, or difficulty breathing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Iodinated contrast media Major
Alcohol Major
Insulin Major
Sulfonylureas Major
Diuretics Moderate
Corticosteroids Moderate
Cationic drugs Moderate
Thiazide diuretics Minor
Thyroid hormones Minor
Beta-blockers Minor

🚨 Major Interactions

  • Iodinated contrast media
  • Alcohol
  • Insulin or sulfonylureas

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, ranitidine, triamterene, trimethoprim, vancomycin)

🍷 Alcohol Interaction

Alcohol should be avoided or strictly limited while taking this medicine because it increases the risk of lactic acidosis (a rare but serious complication of metformin) and can cause dangerous drops in blood sugar. If you choose to drink, do so only occasionally and with food, and inform your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Lactic acidosis is a rare but serious complication; discontinue and seek immediate medical help if suspected.","Temporarily discontinue before iodinated contrast imaging procedures.","Avoid excessive alcohol intake.","Monitor renal function regularly, especially in elderly patients.","Use with caution in patients with heart failure or hypoxic states.","May cause hypoglycemia when combined with insulin or sulfonylureas; monitor blood sugar.","Voglibose may cause gastrointestinal side effects; take with meals.","Not recommended for children and adolescents under 18 years.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Metformin is excreted in breast milk in small amounts and is generally considered compatible with breastfeeding. Voglibose safety during lactation is not established. Consult your doctor before breastfeeding while on this medicine.

💊 Overdose Management

Overdose of this medicine can cause hypoglycemia (if combined with other antidiabetic agents) and lactic acidosis. Symptoms include severe nausea, vomiting, diarrhea, rapid breathing, muscle pain, and extreme weakness. Seek immediate medical attention. Treatment is supportive and may include hemodialysis for metformin overdose. There is no specific antidote for Voglibose.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember with a meal. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine with meals to reduce gastrointestinal side effects and to help Voglibose work properly. Do not skip meals, especially if you are also taking insulin or sulfonylureas, as this can increase the risk of low blood sugar. Drink plenty of water throughout the day to help your kidneys flush out metformin. Avoid excessive alcohol consumption because it can increase the risk of lactic acidosis and low blood sugar. Inform your doctor if you have kidney or liver problems, as the dose may need adjustment. Do not stop or change the dose without consulting your doctor. Monitor your blood sugar regularly as advised. If you are scheduled for a surgery or a contrast-enhanced imaging procedure, tell your doctor about this medicine because it may need to be temporarily stopped.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of metformin accumulation due to age-related decline in renal function, increasing the risk of lactic acidosis. Regular monitoring of kidney function is essential. Dose adjustment may be needed. Voglibose side effects may be more pronounced.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before conception. Metformin is generally considered safe in pregnancy, but Voglibose is not recommended due to lack of safety data. Your doctor may switch you to a safer alternative like insulin.

🏥 Post-Surgery Considerations

This medicine may need to be temporarily stopped before surgery, especially if you will be fasting or undergoing procedures with contrast media. Inform your surgeon and anesthesiologist about your diabetes medication. Blood sugar levels should be monitored closely during the perioperative period.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. If you are fasting or have reduced food intake, your blood sugar may be affected. Monitor your blood sugar and follow your doctor's advice regarding dose adjustments.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to improve insulin sensitivity.
🥗
Engage in regular physical activity like walking, swimming, or cycling.
😴
Follow a balanced diet rich in fiber, lean proteins, and healthy fats.
💧
Monitor your blood sugar regularly as advised by your doctor.
🧘
Get adequate sleep and manage stress to help control blood sugar.
🌞
Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Exercise is beneficial for diabetes management, but be cautious about hypoglycemia if you are also taking insulin or sulfonylureas. Check your blood sugar before and after exercise, and carry fast-acting sugar in case of low blood sugar. Stay hydrated during exercise.

🥗 Diet Recommendations

Include high-fiber foods like whole grains, vegetables, and legumes.
Choose lean proteins such as fish, chicken, and tofu.
Limit intake of refined carbohydrates and sugary drinks.
Eat small, frequent meals to help control blood sugar.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine may cause hypoglycemia, especially when combined with other antidiabetic drugs, which can affect your ability to drive or operate machinery. Monitor your blood sugar regularly and avoid driving if you feel shaky or confused. Inform your employer about your condition if your job involves safety-sensitive tasks.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like lactic acidosis or severe hypoglycemia, seek immediate medical attention. Your doctor may adjust or stop the medicine based on your condition and blood sugar control.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to vitamin B12 deficiency due to metformin, which can cause anemia and nerve problems. Regular monitoring of vitamin B12 levels is advised. Kidney function should be checked at least annually. The combination is generally safe for long-term use when monitored appropriately. Do not stop the medicine without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet and exercise are foundational for managing type 2 diabetes and can reduce medication needs.

Evidence: Well-established
Other oral antidiabetic agents

DPP-4 inhibitors, SGLT2 inhibitors, or GLP-1 receptor agonists may be alternatives based on individual needs.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, people with diabetes are at higher risk of infections, so ensure you are up to date with recommended vaccines such as influenza, pneumococcal, and hepatitis B.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. If crossing time zones, consult your doctor about adjusting the timing of doses. Store at room temperature and avoid leaving it in a hot car. Check customs regulations for carrying prescription medicines internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with type 2 diabetes and post-meal sugar spikes
He was prescribed this medicine after metformin alone failed to control his post-meal glucose. He started taking it with meals as directed. Within a month, his post-meal sugar levels improved significantly, and his HbA1c dropped from 8.5% to 7.2%. He experienced mild bloating initially, which subsided after two weeks.
💡 Lesson: Taking this medicine with meals improves tolerability and effectiveness. Regular monitoring helps track progress.
👤 A 60-year-old woman with type 2 diabetes and mild renal impairment
She was started on this medicine with careful monitoring of kidney function. Her doctor adjusted the dose based on her eGFR. She maintained good glycemic control without any serious side effects. She was advised to avoid alcohol and stay hydrated.
💡 Lesson: In elderly patients with renal impairment, dose adjustment and regular monitoring are crucial for safe use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood sugar within days, but full effects on HbA1c may take 2-3 months. Regular monitoring is important.

Q: Can I take this medicine if I have kidney disease?

A: It depends on the severity of kidney disease. Metformin is contraindicated in severe renal impairment. Consult your doctor for dose adjustment.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember with a meal. If it's almost time for the next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for voglikem-m 0.2 tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure diabetes permanently.
    Fact: This medicine helps control blood sugar but does not cure diabetes. Lifestyle changes and medication are needed long-term.
  • Myth: You can stop taking this medicine once your sugar levels are normal.
    Fact: Stopping without doctor's advice can cause blood sugar to rise again. Always consult your doctor before stopping.
  • Myth: This medicine causes kidney damage.
    Fact: Metformin does not cause kidney damage, but it can accumulate if kidneys are already impaired. Regular monitoring is important.

🔄 Alternative Options

Generic Alternatives

  • Metformin 500 mg + Voglibose 0.2 mg tablet (generic)

Brand Alternatives

  • Advog M 0.2 Tablet SR

📊 Comparison with Similar Medicines

[{"medicine":"Metformin + Voglibose","composition":"Metformin 500 mg + Voglibose 0.2 mg","primary_use":"Type 2 diabetes with postprandial hyperglycemia","key_difference":"Targets both fasting and post-meal sugar"},{"medicine":"Metformin + Glimepiride","composition":"Metformin 500 mg + Glimepiride 1 mg","primary_use":"Type 2 diabetes","key_difference":"Sulfonylurea component increases hypoglycemia risk"},{"medicine":"Metformin + Sitagliptin","composition":"Metformin 500 mg + Sitagliptin 50 mg","primary_use":"Type 2 diabetes","key_difference":"DPP-4 inhibitor has fewer GI side effects"}]

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