ajaduo 25mg/5mg tablet
What is ajaduo 25mg/5mg tablet used for?
Ajaduo (Empagliflozin + Linagliptin) is used to treat ANTI DIABETIC. It contains Empagliflozin (25mg) + Linagliptin (5mg), which Empagliflozin: inhibits SGLT2 in renal proximal tubule, reducing glucose reabsor. Always consult your doctor before use. Take as prescribed.
- Generic Name: Empagliflozin + Linagliptin
- Manufacturer: Lupin Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ ajaduo 25mg/5mg tablet Uses & Benefits
Type 2 diabetes mellitus as adjunct to diet and exercise
Off-label uses: None established
๐ Drug Information
| Generic Name(s) | Empagliflozin + Linagliptin |
| Brand Name | Ajaduo |
| Manufacturer | Lupin Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | SGLT2 inhibitor + DPP-4 inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Empagliflozin: inhibits SGLT2 in renal proximal tubule, reducing glucose reabsorption; Linagliptin: inhibits DPP-4, increasing incretin levels (GLP-1, GIP), enhancing insulin secretion and reducing glucagon
Mechanism Steps
๐ก How to Take ajaduo 25mg/5mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of ajaduo 25mg/5mg tablet
โ Common Side Effects
- Urinary tract infections
- Genital mycotic infections
- Nasopharyngitis
- Headache
- Arthralgia
๐จ Serious Side Effects
- Diabetic ketoacidosis
- Acute kidney injury
- Hypoglycemia (when used with insulin/SU)
- Pancreatitis
- Hypersensitivity reactions
โ ๏ธ Rare Side Effects
- Fournier's gangrene
- Angioedema
- Stevens-Johnson syndrome
- Bullous pemphigoid
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | Increased risk of hypoglycemia |
| Sulfonylureas | Major | Increased risk of hypoglycemia |
| Loop diuretics | Major | Additive diuretic effect, risk of volume depletion |
| ACE inhibitors | Moderate | Additive blood pressure lowering |
| NSAIDs | Moderate | Reduced antihypertensive effect, risk of acute kidney injury |
| Corticosteroids | Moderate | Hyperglycemic effect may reduce efficacy |
๐จ Major Interactions
- Insulin
- Sulfonylureas
- Loop diuretics
โก Moderate Interactions
- ACE inhibitors
- ARBs
- NSAIDs
- Corticosteroids
โน๏ธ Minor Interactions
- Beta-blockers
- Calcium channel blockers
๐ฝ๏ธ Food Interactions
Food delays absorption of empagliflozin but not clinically significant; linagliptin unaffected
๐ท Alcohol Interaction
May increase risk of hypoglycemia
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Severe renal impairment (eGFR <30), end-stage renal disease, dialysis, history of serious hypersensitivity reaction, diabetic ketoacidosis
๐ Monitoring Parameters
Blood glucose, HbA1c, renal function (eGFR), electrolytes, blood pressure, signs of volume depletion
๐คฑ Lactation Safety
Not recommended; unknown if excreted in human milk
๐ Overdose Management
Supportive care; monitor blood glucose, electrolytes, and renal function; hemodialysis unlikely to remove empagliflozin
โฐ Missed Dose
Take as soon as remembered unless almost time for next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.
Found this to be a helpful product. Good results.