Spurge Tablet: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is vitomef d 80mg/250mg capsule used for?
This medicine is a combination of Drotaverine (an antispasmodic) and Mefenamic Acid (an NSAID) used to relieve painful menstrual cramps and smooth muscle spasms. It works by relaxing muscles and reducing pain-causing chemicals. Take it with food to avoid stomach upset.
- Generic Name: Drotaverine (80mg) + Mefenamic Acid (250mg)
- Manufacturer: Apkavit Lifesciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 vitomef d 80mg/250mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा ड्रोटावेरिन और मेफेनामिक एसिड का संयोजन है, जिसका उपयोग मासिक धर्म के दर्दनाक ऐंठन (डिसमेनोरिया) और पेट या आंतों की ऐंठन से होने वाले दर्द को कम करने के लिए किया जाता है। यह मांसपेशियों को आराम देकर और दर्द पैदा करने वाले रसायनों को कम करके काम करती है। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, अल्सर, गुर्दे की समस्या, एलर्जी और लीवर की समस्या हो सकती है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को भोजन या दूध के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ जाता है। बिना डॉक्टर की सलाह के 7 दिनों से अधिक न लें। यदि आपको अल्सर, गुर्दे या लीवर की बीमारी, अस्थमा या हृदय रोग है तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 vitomef d 80mg/250mg capsule Uses & Benefits
[{"condition":"Painful menstrual cramps (dysmenorrhea)","description":"Relieves uterine spasms and reduces pain associated with menstruation.","evidence":"Well-established"},{"condition":"Smooth muscle spasms of the gastrointestinal tract","description":"Helps relax spasms in the intestines and biliary tract, reducing pain.","evidence":"Moderate"},{"condition":"Renal colic","description":"May be used to relieve pain from kidney stones by relaxing smooth muscle.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine headache","description":"Sometimes used off-label for acute migraine relief due to analgesic and antispasmodic effects.","evidence":"Limited"}]
Primary treatment for: Painful menstrual cramps (dysmenorrhea)
Also treats: Gastrointestinal spasms, Renal colic, Biliary colic
📋 Drug Information
| Generic Name(s) | Drotaverine (80mg) + Mefenamic Acid (250mg) |
| Brand Name | vitomef d 80mg/250mg capsule |
| Manufacturer | Apkavit Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Drotaverine is a selective phosphodiesterase-4 (PDE4) inhibitor that increases cyclic adenosine monophosphate (cAMP) levels in smooth muscle cells, leading to relaxation and relief of spasms. Mefenamic Acid is an NSAID that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Together, they provide both antispasmodic and analgesic effects.
Mechanism Steps
💡 How to Take vitomef d 80mg/250mg capsule
Strength: Tablet containing Drotaverine 80 mg and Mefenamic Acid 250 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally 2 to 3 times daily, preferably with food. The dose may be adjusted by your doctor based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use with caution and lower doses may be considered. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor. Not recommended in severe renal impairment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor. Not recommended in severe hepatic impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is 3 tablets (Drotaverine 240 mg + Mefenamic Acid 750 mg). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of vitomef d 80mg/250mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| Antihypertensives | Moderate | |
| SSRIs | Moderate | |
| Cyclosporine | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, aspirin)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (e.g., ACE inhibitors, ARBs, diuretics)
- SSRIs
- Cyclosporine
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver toxicity. It may also enhance drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active peptic ulcer or history of recurrent ulcers","Severe kidney disease","Severe liver disease","Heart failure","Allergy to Drotaverine, Mefenamic Acid, or other NSAIDs","Third trimester of pregnancy","Children under 12 years (safety not established)","Asthma induced by NSAIDs"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol.","Do not use for more than 7 days without medical advice.","Use with caution in elderly patients.","Inform your doctor if you have a history of ulcers, kidney disease, liver disease, asthma, or heart disease.","Do not take other NSAIDs concurrently.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Consult your doctor if you are pregnant or breastfeeding."]
🤱 Lactation Safety
Mefenamic Acid is excreted in breast milk. Limited information is available on Drotaverine. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, stomach pain, bleeding, drowsiness, and kidney failure. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and renal function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine with food or milk to reduce stomach irritation. Do not exceed the recommended dose. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding. Do not use for more than 7 days without consulting a doctor. Inform your doctor if you have a history of ulcers, kidney disease, liver disease, asthma, or heart disease. Do not take other NSAIDs concurrently. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events with NSAIDs. Use with caution, at the lowest effective dose, and for the shortest duration. Monitor renal function and blood pressure regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like Mefenamic Acid may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
Avoid using this medicine after surgery, especially coronary artery bypass graft (CABG) surgery, as NSAIDs increase the risk of bleeding and cardiovascular events. Consult your surgeon for alternative pain management.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase the risk of bleeding. Your dentist may advise you to stop it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may cause abdominal strain while taking this medicine, as it may increase the risk of gastrointestinal bleeding. Light activities like walking are generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, which can affect your daily activities. Take it with food to minimize this.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or kidney problems. Do not stop abruptly if you are on a prescribed regimen without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney problems, and liver toxicity. Regular monitoring of kidney and liver function, and blood counts may be required. It is not recommended for prolonged use without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Applying a heating pad to the lower abdomen can help relieve menstrual cramps.
Evidence: Well-establishedCan complement medicine for chronic pain and muscle spasms.
Evidence: ModerateYoga, meditation, and deep breathing can help reduce muscle tension and pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing times gradually to maintain consistent intervals. Check local customs regulations regarding prescription medicines. Always carry enough supply for your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30-60 minutes after taking it.
A: No, it should be taken with food or milk to reduce stomach upset.
A: Do not take other NSAIDs concurrently as it increases the risk of side effects. Consult your doctor.
A: It is generally avoided during pregnancy, especially in the third trimester. Consult your doctor.
A: Do not use for more than 7 days without consulting your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for vitomef d 80mg/250mg capsule
View AllAlternative brands with exact same active ingredient:
-
colic dm 80mg/250mg tabletJasmine Healthcare India Pvt Ltd ₹5.39 92.9% CHEAPER
-
dimef-dv tabletHealsure Lifesciences Pvt. Ltd. ₹5.63 92.6% CHEAPER
-
drotinam m 80mg/250mg tabletMankind Pharma Ltd ₹17.58 76.9% CHEAPER
-
davaindia drotaverine+mefenamic acid 80mg/250mg tabletDavaindia Generic Pharmacy ₹24.00 68.4% CHEAPER
-
mefen dt 80mg/250mg tabletCureways Remedies ₹28.13 63% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach irritation. - Myth: This medicine is safe to use for long periods without monitoring.
Fact: Prolonged use requires monitoring of kidney and liver function and blood counts. - Myth: This medicine is safe during pregnancy.
Fact: It should be avoided during pregnancy, especially in the third trimester, unless prescribed by a doctor.
🔄 Alternative Options
Generic Alternatives
- Drotaverine + Mefenamic Acid combination tablets from other manufacturers
Brand Alternatives
- Drotin-M
- Drotin-MF
- Spasmindon
- Drotikind-M
- Drota-M