Appime 250mg Injection - Uses, Price, Side Effects
What is appime 250mg injection used for?
Appime 250mg Injection contains Cefepime, a fourth-generation cephalosporin antibiotic. It works by killing bacteria or preventing their growth, effectively treating various bacterial infections such as pneumonia, urinary tract infections, skin infections, and intra-abdominal infections. It is administered intravenously or intramuscularly under medical supervision.
- Generic Name: Cefepime
- Manufacturer: Apkavit Lifesciences
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ appime 250mg injection Uses & Benefits
Treatment of pneumonia, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, febrile neutropenia.
Off-label uses: Meningitis, Osteomyelitis
๐ Drug Information
| Generic Name(s) | Cefepime |
| Brand Name | Appime 250mg Injection |
| Manufacturer | Apkavit Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 4th generation |
| Route of Administration | Intravenous (IV) or intramuscular (IM) |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis.
Mechanism Steps
๐ก How to Take appime 250mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of appime 250mg injection
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Injection site reactions
๐จ Serious Side Effects
- Anaphylaxis
- Clostridioides difficile colitis
- Seizures
- Acute renal failure
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Agranulocytosis
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aminoglycosides | Moderate | Increased nephrotoxicity |
| Probenecid | Moderate | Reduced excretion of cefepime |
๐จ Major Interactions
- Aminoglycosides
- Loop diuretics
- Probenecid
โก Moderate Interactions
- Warfarin
- Oral contraceptives
โน๏ธ Minor Interactions
- Antacids
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cefepime or other cephalosporins, penicillins, or beta-lactam antibiotics.
๐ Monitoring Parameters
Renal function, complete blood count, signs of hypersensitivity, superinfection.
๐คฑ Lactation Safety
Excreted in breast milk in low concentrations; use with caution.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Administer as soon as remembered; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for appime 250mg injection
View AllAlternative brands with exact same active ingredient (Cefepime (250mg)):
-
cachepime 250mg injectionCachet Pharmaceuticals Pvt Ltd โน33.75 20% CHEAPER
-
cefetune 250mg injectionFortune Labs โน45.00 6.7% COSTLIER
-
biopime 250mg injectionBiochem Pharmaceutical Industries โน46.83 11% COSTLIER
-
curepime 250mg injectionMancure Drugs Pvt Ltd โน46.88 11.1% COSTLIER
-
cepime 250mg injectionAlembic Pharmaceuticals Ltd โน47.34 12.2% COSTLIER
-
corpime 250mg injectionCoral Pharmaceuticals P Ltd โน50.00 18.5% COSTLIER
-
enpime 250mg injectionShrinivas Gujarat Laboratories Pvt Ltd โน50.00 18.5% COSTLIER
-
godpime 250mg injectionGodrams Lifeline โน50.00 18.5% COSTLIER
-
lepime 250mg injectionImpileo Lifescience โน50.00 18.5% COSTLIER
-
abdopime 250mg injectionOdin Healthcare Pvt Ltd โน51.25 21.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.