vinoryl tablet - Caffeine (30mg) + Chlorpheniramine Maleate (2mg) medicine

Agicold Tablet: Comprehensive Medicine Guide

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🏭 Remeris Pharma Pvt. Ltd. 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic rhinitis and urticaria; established for common cold.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, tongue, or throat
  • Severe dizziness or fainting
  • Fast, irregular, or pounding heartbeat
  • Inability to urinate or severe difficulty passing urine
  • Seizures or convulsions
  • Yellowing of skin or eyes, dark urine, or severe abdominal pain
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is vinoryl tablet used for?

This medicine is a combination of Caffeine and Chlorpheniramine Maleate used to relieve allergy and cold symptoms such as sneezing, runny nose, and itchy eyes. It works by blocking histamine and reducing drowsiness.

  • Generic Name: Caffeine (30mg) + Chlorpheniramine Maleate (2mg)
  • Manufacturer: Remeris Pharma Pvt. Ltd.
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 vinoryl tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी और सर्दी के लक्षणों जैसे छींक आना, नाक बहना, आंखों में खुजली और पानी आना, और त्वचा पर खुजली वाले दाने को कम करने के लिए उपयोग की जाती है। इसमें कैफीन और क्लोरफेनिरामाइन मेलिएट होते हैं। क्लोरफेनिरामाइन हिस्टामिन को ब्लॉक करता है जिससे एलर्जी के लक्षण कम होते हैं, और कैफीन नींद को कम करने में मदद करता है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, और पेट में गड़बड़ी शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि आपको गंभीर एलर्जी, दिल की धड़कन तेज होना, या पेशाब करने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। निर्धारित मात्रा से अधिक न लें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या मशीनरी चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब का सेवन न करें। यदि आपको ग्लूकोमा, प्रोस्टेट की समस्या, या हृदय रोग है तो अपने डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 vinoryl tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Reduces itching and hives associated with allergic skin reactions.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from sneezing, runny nose, and watery eyes associated with the common cold.","evidence":"Established"},{"condition":"Allergic conjunctivitis","description":"Helps relieve itching and redness of the eyes due to allergies.","evidence":"Limited"}]

Off-label uses: [{"condition":"Insomnia due to allergies","description":"Sometimes used off-label for its sedative effects in allergic patients with sleep disturbance.","evidence":"Limited"},{"condition":"Motion sickness","description":"Occasionally used off-label for prevention of motion sickness due to anticholinergic effects.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Urticaria, Common cold, Allergic conjunctivitis

📋 Drug Information

Generic Name(s)Caffeine (30mg) + Chlorpheniramine Maleate (2mg)
Brand Namevinoryl tablet
ManufacturerRemeris Pharma Pvt. Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk if it causes stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not consume alcohol while taking this medicine as it increases drowsiness.
4
Limit caffeine intake from coffee, tea, or cola to avoid jitteriness or palpitations.
5
Do not use this medicine for more than 7 days without consulting your doctor.
6
Inform your doctor if you have glaucoma, prostate enlargement, or heart disease before taking this medicine.
7
Keep a record of your symptoms to help your doctor assess the effectiveness of the treatment.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Sneezing
This medicine is commonly prescribed for this.
Likely Use
Runny nose
This medicine helps reduce nasal secretions.
Likely Use
Itchy, watery eyes
This medicine relieves allergic eye symptoms.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Body ache
This medicine is not a pain reliever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine Maleate is well absorbed from the gastrointestinal tract after oral administration. Caffeine is also rapidly and completely absorbed from the gastrointestinal tract. Food may slightly delay the absorption of both components but does not significantly affect the extent of absorption.
DistributionChlorpheniramine Maleate is widely distributed throughout the body, including the central nervous system. It crosses the blood-brain barrier and placenta. Caffeine is distributed throughout all body fluids and tissues, also crossing the blood-brain barrier and placenta.
Protein BindingChlorpheniramine Maleate is approximately 70% bound to plasma proteins. Caffeine is approximately 10-35% bound to plasma proteins.
MetabolismChlorpheniramine Maleate is extensively metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2D6 and CYP3A4. Caffeine is metabolized in the liver by CYP1A2, CYP2E1, and CYP3A4, with the major metabolites being paraxanthine, theobromine, and theophylline.
Half-LifeThe elimination half-life of Chlorpheniramine Maleate is approximately 12-43 hours, with considerable interindividual variability. The elimination half-life of Caffeine is approximately 3-7 hours in healthy adults, but it can be prolonged in individuals with hepatic impairment or in neonates.
ExcretionChlorpheniramine Maleate and its metabolites are primarily excreted in the urine. Caffeine and its metabolites are also excreted mainly in the urine, with only a small fraction excreted unchanged.
BioavailabilityThe oral bioavailability of Chlorpheniramine Maleate is approximately 25-50% due to first-pass metabolism. Caffeine has nearly 100% oral bioavailability.
Onset of ActionThe onset of action for Chlorpheniramine Maleate is typically within 30-60 minutes after oral administration. Caffeine's stimulant effects begin within 15-30 minutes.
Peak Plasma TimePeak plasma concentrations of Chlorpheniramine Maleate are reached approximately 2-6 hours after oral administration. Caffeine reaches peak plasma levels within 30-60 minutes.
Duration of ActionThe antihistaminic effect of Chlorpheniramine Maleate lasts approximately 4-6 hours, while the stimulant effect of Caffeine lasts about 3-5 hours.

How It Works

This medicine combines two active ingredients. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract. This action prevents histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Caffeine is a central nervous system stimulant that antagonizes adenosine receptors, leading to increased neuronal activity and release of neurotransmitters. It also constricts cerebral blood vessels and stimulates the respiratory center. The combination helps alleviate allergic symptoms while reducing the sedation caused by Chlorpheniramine.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine Maleate binds to H1 receptors on target cells, preventing histamine from binding and triggering allergic responses.
2
Reduction of allergic symptoms: This blockade reduces vasodilation, capillary permeability, and sensory nerve stimulation, alleviating sneezing, runny nose, and itching.
3
Adenosine receptor antagonism: Caffeine blocks adenosine A1 and A2A receptors in the brain, increasing neuronal firing and neurotransmitter release.
4
Central nervous system stimulation: This leads to increased alertness, reduced drowsiness, and improved psychomotor performance, counteracting the sedative effect of Chlorpheniramine.

💡 How to Take vinoryl tablet

Strength: Tablet containing Caffeine 30 mg and Chlorpheniramine Maleate 2 mg.

1Take this medicine orally with a glass of water.
2It can be taken with or without food. If stomach upset occurs, take with food or milk.
3Swallow the tablet whole; do not crush or chew.
4Take exactly as prescribed by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally every 4 to 6 hours as needed for symptoms, not to exceed 6 tablets in 24 hours. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of Chlorpheniramine Maleate, especially anticholinergic effects and drowsiness. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 6 tablets in 24 hours for adults. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals if stomach upset occurs
Reduces gastrointestinal discomfort.
Grapefruit juice
Avoid or limit
May increase drug levels and side effects.
Caffeine-containing beverages
Limit intake
Additive stimulant effects may cause jitteriness or palpitations.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of vinoryl tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-15%))
Sip water, chew sugar-free gum, or use saliva substitutes. Consult if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid alcohol.
Nausea (Uncommon (1-5%))
Take with food or milk to reduce stomach upset.
Blurred vision (Uncommon (1-5%))
Avoid tasks requiring clear vision until it resolves. Consult if persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, tongue, throat, difficulty breathing, or severe rash.
Palpitations or arrhythmias (Rare (<0.1%))
Contact your doctor immediately if you experience fast, irregular, or pounding heartbeat.
Urinary retention (Rare (<0.1%))
Seek medical attention if you are unable to urinate or have difficulty passing urine.
Seizures (Very rare (<0.01%))
Call emergency services if seizures occur.

⚠️ Rare Side Effects

Blood dyscrasias (e.g., agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor promptly.
Hepatotoxicity
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Alcohol Major
Anticholinergics Major
CYP2D6 inhibitors Moderate
CYP1A2 inhibitors Moderate
Sedative-hypnotics Moderate
Antacids Minor
Oral contraceptives Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Alcohol and other CNS depressants
  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)

⚡ Moderate Interactions

  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
  • CYP1A2 inhibitors (e.g., ciprofloxacin, fluvoxamine)
  • Sedative-hypnotics (e.g., benzodiazepines, zolpidem)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair your ability to drive or operate machinery. It may also increase the risk of other side effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Chlorpheniramine Maleate, Caffeine, or any component of the formulation","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Severe liver disease","Concurrent use with monoamine oxidase inhibitors (MAOIs)","Severe hypertension or cardiac arrhythmias","Children under 12 years of age (unless directed by a doctor)"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, prostatic hypertrophy, urinary retention, or cardiovascular disease.","May cause dry mouth, blurred vision, or constipation due to anticholinergic effects.","Do not use for prolonged periods without medical advice.","Keep out of reach of children.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Chlorpheniramine Maleate and Caffeine are excreted in breast milk. Chlorpheniramine may cause drowsiness or irritability in nursing infants. Caffeine may accumulate in the infant and cause stimulation. Consult your doctor before using this medicine while breastfeeding; alternative options may be preferred.

💊 Overdose Management

Overdose may cause severe drowsiness, dizziness, tachycardia, tremors, seizures, or respiratory depression. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid consuming alcohol or other central nervous system depressants while taking this medicine, as they can increase drowsiness and dizziness. Inform your doctor if you have glaucoma, prostate enlargement, urinary retention, liver or kidney disease, or heart problems. Do not use this medicine for longer than directed without medical advice. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the anticholinergic and sedative effects of Chlorpheniramine Maleate. They may experience increased drowsiness, confusion, dry mouth, and urinary retention. Use with caution and consider lower doses. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Chlorpheniramine Maleate and Caffeine are classified as FDA Pregnancy Category B, but use should be discussed with your healthcare provider to weigh benefits and risks.

🏥 Post-Surgery Considerations

This medicine may cause drowsiness and dry mouth, which can affect recovery after surgery. Inform your surgeon and anesthesiologist about all medications you are taking. It is generally advisable to avoid this medicine before surgery unless approved by your doctor.

🦷 Dental Procedures

This medicine can cause dry mouth, which may increase the risk of dental caries and oral discomfort. Inform your dentist if you are taking this medicine. It may also interact with sedatives used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Identify and avoid allergens that trigger your symptoms.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Maintain good hydration to reduce dry mouth.
💧
Get adequate rest to support your immune system.
🧘
Practice good hand hygiene to prevent colds.
🌞
Consider using saline nasal rinses for nasal congestion.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Stay hydrated during exercise.

🥗 Diet Recommendations

Include foods rich in vitamin C to support immune function.
Avoid known food allergens.
Limit caffeine intake from coffee, tea, and energy drinks.
Stay well hydrated.
Eat a balanced diet to support overall health.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job requires alertness.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, dependence, and increased risk of side effects such as cognitive impairment, urinary retention, and anticholinergic effects. Regular monitoring by a doctor is recommended if prolonged use is necessary. It is not intended for long-term management of allergies without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Identifying and avoiding triggers can reduce the need for medication.

Evidence: Well-established
Saline nasal irrigation

Helps clear nasal passages and reduce congestion.

Evidence: Established
Second-generation antihistamines

Options like loratadine or cetirizine cause less drowsiness.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If crossing time zones, continue your regular dosing schedule as prescribed. Check customs regulations for carrying medications. Keep a list of your medications and allergies with you.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergic rhinitis
She was prescribed this medicine for sneezing and runny nose during spring. She noticed relief within 30 minutes of taking the tablet. She experienced mild drowsiness initially but it decreased after a few days. She was advised to avoid driving until she knew how the medicine affected her.
💡 Lesson: This medicine provides rapid relief from allergic symptoms, but initial drowsiness may occur. Avoid driving until you know your response.
👤 A 50-year-old man with urticaria
He developed itchy hives after eating a new food. His doctor prescribed this medicine. The itching and hives subsided within a few hours. He was cautioned not to take more than the recommended dose and to avoid alcohol.
💡 Lesson: This medicine effectively relieves itching and hives. Adhere to the prescribed dose and avoid alcohol to prevent increased drowsiness.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after oral administration.

Q: Can I take this medicine on an empty stomach?

A: It can be taken with or without food, but if it causes stomach upset, take it with food or milk.

Q: Is it safe to take this medicine with other antihistamines?

A: No, taking multiple antihistamines can increase side effects. Consult your doctor before combining.

Q: How long can I continue this medicine?

A: It is intended for short-term use. Do not use for more than 7 days without consulting your doctor.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • Can I take it with other cold medicines?

🔄 Substitutes for vinoryl tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Agicold Tablet can cure the common cold.
    Fact: This medicine only provides symptomatic relief; it does not cure the underlying viral infection.
  • Myth: Agicold Tablet is safe to take with alcohol.
    Fact: Alcohol increases drowsiness and dizziness, and should be avoided.
  • Myth: Agicold Tablet can be taken long-term for allergies.
    Fact: It is intended for short-term use. Long-term use requires medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Caffeine 30 mg + Chlorpheniramine Maleate 2 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Agicold Tablet","composition":"Caffeine 30 mg + Chlorpheniramine Maleate 2 mg","uses":"Allergic rhinitis, urticaria, common cold","sedation":"Moderate (reduced by caffeine)"},{"medicine":"Chlorpheniramine Maleate 2 mg tablet","composition":"Chlorpheniramine Maleate 2 mg","uses":"Allergic rhinitis, urticaria","sedation":"High"},{"medicine":"Caffeine 30 mg tablet","composition":"Caffeine 30 mg","uses":"Stimulant","sedation":"None"}]

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