Defluvox 50mg Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Thoughts of harming yourself or others
- Agitation, hallucinations, rapid heart rate, fever, or muscle stiffness
- Unusual bleeding or bruising
- Severe headache with visual changes
- Confusion, weakness, or seizures
- Yellowing of skin or eyes
- Eye pain or vision changes
If experiencing severe symptoms, call emergency services immediately.
What is uvox tablet used for?
This medicine is an SSRI antidepressant used to treat OCD, depression, social anxiety disorder, and panic disorder. It works by increasing serotonin levels in the brain. The usual starting dose is 50 mg once daily at bedtime, and it may take several weeks to work fully.
- Generic Name: Fluvoxamine (50mg)
- Manufacturer: Abbott
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 uvox tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फ्लुवोक्सामिन 50 मिलीग्राम की गोली है, जो एसएसआरआई वर्ग की एंटीडिप्रेसेंट दवा है। इसका उपयोग मुख्य रूप से ऑब्सेसिव-कंपल्सिव डिसऑर्डर (ओसीडी), अवसाद, सामाजिक चिंता विकार और पैनिक डिसऑर्डर के इलाज के लिए किया जाता है। यह मस्तिष्क में सेरोटोनिन के स्तर को बढ़ाकर मूड और चिंता को नियंत्रित करने में मदद करती है। इस दवा को डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, नींद आना, अनिद्रा, मुंह सूखना, सिरदर्द और दस्त शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन सेरोटोनिन सिंड्रोम, रक्तस्राव का खतरा, और युवाओं में आत्महत्या के विचार हो सकते हैं। यदि आपको बेचैनी, भ्रम, तेज धड़कन, बुखार या असामान्य रक्तस्राव हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। डॉक्टर की सलाह के बिना इसे अचानक बंद न करें। इस दवा के साथ शराब न पिएं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या मशीनरी चलाने से बचें। अपने डॉक्टर को अपनी सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में बताएं। यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं या स्तनपान करा रही हैं, तो अपने डॉक्टर से सलाह लें।
💊 uvox tablet Uses & Benefits
- [{"condition":"Obsessive-compulsive disorder (OCD)","description":"This medicine is FDA-approved for the treatment of OCD in adults and children aged 8 years and older.
- It helps reduce the frequency and intensity of obsessions and compulsions.","evidence":"Well-established"},{"condition":"Major depressive disorder","description":"This medicine is used to treat depression in adults, helping to improve mood, energy, and interest in daily activities.","evidence":"Well-established"},{"condition":"Social anxiety disorder","description":"This medicine is approved for social anxiety disorder in adults, reducing anxiety and avoidance in social situations.","evidence":"Well-established"},{"condition":"Panic disorder","description":"This medicine is used to treat panic disorder in adults, reducing the frequency and severity of panic attacks.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Post-traumatic stress disorder (PTSD)","description":"Sometimes prescribed off-label to reduce PTSD symptoms such as flashbacks and anxiety.","evidence":"Limited"},{"condition":"Generalized anxiety disorder (GAD)","description":"May be used off-label for chronic excessive worry and anxiety.","evidence":"Limited"},{"condition":"Premenstrual dysphoric disorder (PMDD)","description":"Occasionally used off-label for severe premenstrual mood symptoms.","evidence":"Limited"}]
Primary treatment for: Obsessive-compulsive disorder (OCD)
Also treats: Major depressive disorder, Social anxiety disorder, Panic disorder
📋 Drug Information
| Generic Name(s) | Fluvoxamine (50mg) |
| Brand Name | uvox tablet |
| Manufacturer | Abbott |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Selective Seretonin Reuptake inhibitors (SSRIs) |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 20°C and 25°C (68°F to 77°F). Keep it in a dry place, away from moisture and heat. Keep the container tightly closed. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Check the expiry date on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the reuptake of serotonin (5-hydroxytryptamine, 5-HT) at the presynaptic neuronal membrane. This inhibition increases the concentration of serotonin in the synaptic cleft, enhancing serotonergic neurotransmission. The exact mechanism by which this leads to antidepressant and anti-obsessional effects is not fully understood, but it is thought to involve downstream changes in receptor sensitivity and neuroplasticity.
Mechanism Steps
💡 How to Take uvox tablet
Strength: This medicine is available as an immediate-release tablet containing 50 mg of fluvoxamine.
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for adults is 50 mg once daily at bedtime. The dose may be increased gradually every 4 to 7 days as tolerated, up to a maximum of 300 mg per day. For OCD, the recommended starting dose is 50 mg once daily, with a maximum of 300 mg per day. For depression, the starting dose is 50 mg once daily, with a maximum of 300 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | For children with OCD, the recommended starting dose is 25 mg once daily at bedtime for children aged 8 to 17 years. The dose may be increased gradually every 4 to 7 days up to a maximum of 200 mg per day. Pediatric dosing is not established from available information for other indications. Consult a pediatrician. |
| Elderly Dosage | Elderly patients should start with a lower dose, such as 25 mg once daily, and increase slowly. The maximum dose should not exceed 300 mg per day. Close monitoring is recommended due to increased risk of side effects. |
| Renal Impairment | No specific dosage adjustment is provided in the labeling for renal impairment. However, caution is advised in patients with severe renal impairment. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with hepatic impairment, the starting dose should be reduced, and the dose should be titrated slowly. The maximum dose should be lower than in patients with normal hepatic function. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 300 mg per day for adults. For children, the maximum is 200 mg per day. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of uvox tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Triptans | Major | |
| Warfarin | Major | |
| Clozapine | Major | |
| Theophylline | Major | |
| TCAs | Moderate | |
| Benzodiazepines | Moderate | |
| NSAIDs | Moderate | |
| Alcohol | Moderate | |
| Caffeine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Triptans
- Warfarin
- Clozapine
- Theophylline
⚡ Moderate Interactions
- Tricyclic antidepressants (TCAs)
- Benzodiazepines
- NSAIDs
- Alcohol
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and impair judgment. It may also worsen depression and anxiety symptoms.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Concomitant use with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing an MAOI","Concomitant use with pimozide","Concomitant use with thioridazine","Hypersensitivity to fluvoxamine or any component of the formulation"]
⚠️ Warnings & Precautions
["Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. Monitor closely for clinical worsening and unusual changes in behavior.","Serotonin syndrome may occur with concomitant use of serotonergic drugs. Monitor for symptoms and discontinue if suspected.","Increased risk of bleeding, especially with concomitant use of NSAIDs, aspirin, or warfarin.","Hyponatremia may occur, especially in elderly patients. Monitor sodium levels.","May cause angle-closure glaucoma. Advise patients to report eye pain or vision changes.","Do not stop abruptly to avoid withdrawal symptoms. Taper gradually under medical supervision."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
In case of overdose, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, drowsiness, tachycardia, and dizziness. There is no specific antidote. Treatment should be symptomatic and supportive, including gastric lavage if appropriate, and monitoring of vital signs and cardiac rhythm.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop suddenly without medical advice. Avoid alcohol while taking this medicine, as it can increase drowsiness and impair judgment. Be cautious when driving or operating machinery until you know how this medicine affects you. Inform your doctor about all other medications, supplements, and herbal products you are taking, especially MAOIs, triptans, and blood thinners. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits with your doctor. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and hyponatremia. Start with a lower dose and monitor closely. Regular monitoring of sodium levels and renal function is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor about the risks and benefits of continuing this medicine. It is important to weigh the risk of untreated depression or OCD against the potential risks of the medication. Do not stop the medicine without medical advice.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain anesthetic agents and increase the risk of serotonin syndrome. Your doctor may advise you to temporarily adjust or stop the medicine before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth, which can increase the risk of dental problems. Maintain good oral hygiene and stay hydrated. There are no major interactions with dental anesthetics, but consult your doctor if you have concerns.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or dizziness, especially when you first start taking it. Avoid strenuous exercise or activities that require alertness until you know how it affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, dizziness, or difficulty concentrating, especially during the first few weeks. Avoid driving or operating heavy machinery until you know how it affects you. It may also affect your ability to perform tasks that require mental alertness. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor may gradually reduce the dose to prevent withdrawal symptoms.
📅 Long-Term Use Effects
Long-term use of this medicine may require periodic monitoring of liver function, sodium levels, and mood. Some patients may experience sexual dysfunction, weight changes, or emotional blunting. Regular follow-up with your doctor is important to assess the ongoing benefit and adjust the dose if needed. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
CBT is an effective non-drug treatment for OCD, depression, and anxiety disorders. It can be used alone or in combination with medication.
Evidence: Well-establishedThese practices can help reduce stress and anxiety, complementing medical treatment.
Evidence: ModeratePhysical activity can improve mood and reduce symptoms of depression and anxiety.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust the timing of your dose gradually to maintain consistent blood levels. Check local customs regulations for controlled substances.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may take 1 to 2 weeks for anxiety symptoms and 4 to 6 weeks for full antidepressant and anti-obsessional effects.
A: No, you should not stop this medicine abruptly as it can cause withdrawal symptoms. Consult your doctor for a gradual taper.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is Pregnancy Category C. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for uvox tablet
View AllAlternative brands with exact same active ingredient:
-
fluoxa 50mg tabletElite Pharma Pvt Ltd ₹79.69 66.3% CHEAPER
-
voxazen 50mg tabletZenith Healthcare Ltd ₹87.89 62.8% CHEAPER
-
arkavoxin 50mg tabletRKG Pharma ₹94.22 60.2% CHEAPER
-
psyvoxin 50 tabletPsycormedies ₹96.19 59.3% CHEAPER
-
exame 50mg tabletSunrise Remedies Pvt Ltd ₹100.00 57.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is addictive.
Fact: This medicine is not considered addictive, but it can cause withdrawal symptoms if stopped abruptly. It should be tapered gradually under medical supervision. - Myth: This medicine works immediately.
Fact: This medicine may take 1 to 2 weeks for anxiety symptoms and 4 to 6 weeks for full antidepressant effects. - Myth: This medicine changes your personality.
Fact: This medicine does not change your personality. It helps restore normal serotonin levels to improve mood and reduce anxiety.
🔄 Alternative Options
Generic Alternatives
- Fluvoxamine 50 mg tablet
Brand Alternatives
- Defluvox 50mg Tablet