ursolid 150 tablet - Ursodeoxycholic Acid (150mg) medicine

Hepakind 150 Tablet: Complete Medicine Guide

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🏭 Leeford Healthcare Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for gallstone dissolution and primary biliary cholangitis; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe abdominal pain that does not go away
  • Yellowing of the skin or eyes (jaundice)
  • Dark urine or pale stools
  • Signs of allergic reaction: rash, itching, swelling of face, lips, or throat, difficulty breathing
  • Persistent nausea or vomiting
  • Unexplained fatigue or weakness
  • Fever with chills

If experiencing severe symptoms, call emergency services immediately.

What is ursolid 150 tablet used for?

This medicine contains Ursodeoxycholic Acid 150 mg, used to dissolve cholesterol gallstones and treat certain liver diseases. It works by reducing cholesterol in bile and protecting liver cells. It is a prescription medicine and should be taken under medical supervision.

  • Generic Name: Ursodeoxycholic Acid (150mg)
  • Manufacturer: Leeford Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ursolid 150 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा अर्सोडीऑक्सीकोलिक एसिड 150 मिलीग्राम युक्त है और मुख्य रूप से पित्ताशय की पथरी को घोलने और कुछ जिगर की बीमारियों के इलाज के लिए उपयोग की जाती है। यह प्राइमरी बिलियरी कोलैंगाइटिस नामक जिगर की बीमारी में भी लाभकारी है। यह दवा पित्त में कोलेस्ट्रॉल की मात्रा को कम करके और जिगर की कोशिकाओं की रक्षा करके काम करती है। यह केवल डॉक्टर के पर्चे पर ही ली जानी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, कब्ज, पेट में असहजता और सिरदर्द शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको तेज पेट दर्द, त्वचा या आंखों का पीला पड़ना, गहरे रंग का पेशाब, या एलर्जी के लक्षण जैसे चकत्ते, खुजली, चेहरे, होंठ या गले में सूजन, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं, या स्तनपान करा रही हैं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, क्योंकि यह दवा कुछ दवाओं के साथ परस्पर क्रिया कर सकती है। एल्युमिनियम युक्त एंटासिड के साथ इस दवा को एक साथ न लें। इस दवा को लेते समय शराब का सेवन न करें। यदि आपको चक्कर आते हैं तो वाहन चलाने या मशीनरी चलाने से बचें। इस दवा को बच्चों की पहुंच से दूर रखें और कमरे के तापमान पर सूखी जगह पर स्टोर करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 ursolid 150 tablet Uses & Benefits

[{"condition":"Cholesterol gallstones","description":"Used to dissolve small, cholesterol-rich gallstones in patients who cannot undergo surgery or who have a high risk of surgical complications.","evidence":"Well-established"},{"condition":"Primary biliary cholangitis","description":"Used to improve liver function and delay disease progression in patients with primary biliary cholangitis, a chronic liver disease.","evidence":"Well-established"},{"condition":"Cholestatic liver disease","description":"Used to treat various cholestatic liver conditions, including those associated with cystic fibrosis, to improve bile flow and reduce liver damage.","evidence":"Moderate"},{"condition":"Biliary dyskinesia","description":"Sometimes used to relieve symptoms of biliary dyskinesia, a condition where the gallbladder does not empty properly.","evidence":"Limited"}]

Off-label uses: [{"condition":"Non-alcoholic steatohepatitis (NASH)","description":"Sometimes prescribed off-label to improve liver enzymes in patients with non-alcoholic steatohepatitis, though evidence is limited.","evidence":"Limited"},{"condition":"Liver transplant rejection prophylaxis","description":"Occasionally used off-label to prevent rejection after liver transplantation, but not routinely recommended.","evidence":"Limited"}]

Primary treatment for: Cholesterol gallstones

Also treats: Primary biliary cholangitis, Cholestatic liver disease, Cystic fibrosis-related liver disease

📋 Drug Information

Generic Name(s)Ursodeoxycholic Acid (150mg)
Brand Nameursolid 150 tablet
ManufacturerLeeford Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassHepatoprotectives
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to reduce stomach upset and improve absorption.
2
Stay well hydrated throughout the day to help bile flow.
3
Avoid alcohol while taking this medicine to prevent liver damage.
4
Do not take aluminum-containing antacids within 2 hours of this medicine.
5
Keep all follow-up appointments for liver function tests and ultrasound monitoring.
6
Report any unusual symptoms like severe abdominal pain or yellowing of eyes immediately.
7
Do not stop taking this medicine without consulting your doctor, even if you feel better.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Right upper abdominal pain
This medicine is commonly prescribed for gallstone-related pain.
Likely Use
Jaundice
This medicine is used for cholestatic liver diseases that can cause jaundice.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Headache
This medicine is not used for headache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the small intestine after oral administration. The absorption rate is variable and depends on the formulation and the presence of food. Peak plasma concentrations are usually reached within 1 to 3 hours after a single oral dose.
DistributionThis medicine is widely distributed in the body, with high concentrations in the liver, bile, and small intestine. It is also found in the gallbladder and portal circulation. It crosses the placenta and is excreted in breast milk in small amounts.
Protein BindingThis medicine is highly bound to plasma proteins, primarily albumin, with a binding rate of approximately 96-99%.
MetabolismThis medicine is metabolized in the liver by conjugation with glycine or taurine to form glyco- and tauro-ursodeoxycholic acid. These conjugates are then further metabolized by intestinal bacteria to form lithocholic acid and other metabolites.
Half-LifeThe elimination half-life of this medicine is approximately 3.5 to 5.8 days.
ExcretionThis medicine is primarily excreted in the feces via bile. A small amount is excreted in the urine. After oral administration, about 50-70% of the dose is excreted in feces, mainly as metabolites.
BioavailabilityThe oral bioavailability of this medicine is approximately 30-60%, but it varies widely among individuals due to first-pass metabolism and differences in absorption.
Onset of ActionThe onset of action for gallstone dissolution is gradual and may take several months of continuous therapy. For cholestatic liver diseases, improvement in liver enzymes may be seen within a few weeks.
Peak Plasma TimePeak plasma concentrations are reached within 1 to 3 hours after oral administration.
Duration of ActionThe duration of action depends on the indication. For gallstone dissolution, continuous therapy for months is required. For cholestatic liver diseases, the effect lasts as long as the medicine is taken.

How It Works

This medicine works by replacing the natural bile acids in the body with ursodeoxycholic acid, which is less toxic to liver cells. It reduces the cholesterol content of bile by decreasing cholesterol absorption and secretion into bile, which helps dissolve cholesterol gallstones. Additionally, it protects liver cells from the harmful effects of toxic bile acids and stimulates bile flow, which helps relieve cholestasis.

Mechanism Steps

1
Reduction of cholesterol in bile: This medicine reduces the amount of cholesterol secreted into bile by inhibiting its absorption in the intestine and decreasing its synthesis in the liver.
2
Dispersion of cholesterol: It helps disperse cholesterol in bile, making it less likely to form crystals and stones.
3
Protection of liver cells: This medicine replaces toxic bile acids in the liver, protecting liver cells from damage.
4
Stimulation of bile flow: It promotes the flow of bile through the bile ducts, which helps relieve cholestasis.

💡 How to Take ursolid 150 tablet

Strength: This medicine is available as a 150 mg immediate-release tablet for oral administration.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take it with food to reduce stomach upset.
4If you are taking antacids containing aluminum, take this medicine at least 2 hours before or after them.
5Do not crush, chew, or break the tablet unless your doctor advises otherwise.
6Follow a consistent schedule to help you remember to take your doses.

Dosage Information

Adult DosageThe usual adult dose of this medicine for dissolving gallstones is 8-10 mg per kg of body weight per day, divided into 2-3 doses. For primary biliary cholangitis, the typical dose is 13-15 mg per kg per day, divided into 2-4 doses. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose without consulting your doctor.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients, but they should be monitored for liver and kidney function. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is recommended for patients with renal impairment. However, use with caution and monitor renal function.
Hepatic ImpairmentNo specific dose adjustment is recommended for patients with hepatic impairment. However, use with caution and monitor liver function regularly.
Maximum Daily DoseThe maximum recommended daily dose is 15 mg per kg of body weight, but this may vary based on the indication. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves absorption.
High-fiber foods
Take with caution
May reduce absorption of this medicine.
Aluminum-containing antacids
Avoid taking together
They can bind to this medicine and reduce its absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ursolid 150 tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take the medicine with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (1-10%))
Stay hydrated. If diarrhea is severe or persistent, contact your doctor.
Constipation (Common (1-10%))
Increase fiber and fluid intake. Consult your doctor if it continues.
Stomach discomfort (Common (1-10%))
Take with meals. If pain is severe, seek medical advice.
Headache (Uncommon (0.1-1%))
Rest and stay hydrated. Consult your doctor if headache is severe or persistent.

🚨 Serious Side Effects

Severe abdominal pain (Rare (<0.1%))
Seek immediate medical attention.
Jaundice (yellowing of skin or eyes) (Rare (<0.1%))
Contact your doctor immediately.
Allergic reaction (rash, itching, swelling, difficulty breathing) (Rare (<0.1%))
Seek emergency medical help.
Dark urine (Rare (<0.1%))
Consult your doctor promptly.

⚠️ Rare Side Effects

Calcification of gallstones
Report to your doctor; may require discontinuation.
Liver enzyme elevation
Your doctor may monitor liver function; report any symptoms.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Aluminum-containing antacids Major
Cholestyramine Major
Colestipol Major
Ciprofloxacin Moderate
Nitrendipine Moderate
Oral contraceptives Minor

🚨 Major Interactions

  • Aluminum-containing antacids
  • Cholestyramine, colestipol, colesevelam

⚡ Moderate Interactions

  • Ciprofloxacin
  • Nitrendipine

🍷 Alcohol Interaction

Avoid drinking alcohol while taking this medicine, as alcohol can increase the risk of liver damage and may worsen your condition.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Complete obstruction of the bile ducts","Acute inflammation of the gallbladder or bile ducts","Calcified gallstones","Gallstones larger than 15 mm in diameter","Hypersensitivity to ursodeoxycholic acid or any component of the formulation","Non-functioning gallbladder"]

⚠️ Warnings & Precautions

["Use with caution in patients with liver disease; regular monitoring of liver function is required.","Patients with gallstones should have periodic ultrasound examinations to monitor stone size and calcification.","This medicine may reduce the absorption of other medicines; separate administration times.","Avoid alcohol consumption during treatment.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not use this medicine for gallstones that are radio-opaque (calcified) on X-ray.","If you experience severe abdominal pain, seek immediate medical attention."]

🤱 Lactation Safety

It is not known whether this medicine is excreted in human breast milk. It should be used with caution in breastfeeding women, and only if the potential benefit justifies the potential risk to the infant.

💊 Overdose Management

There is no specific antidote for overdose with this medicine. In case of overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor liver function and vital signs.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before taking this medicine, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also inform your doctor about all other medicines you are taking, including prescription, over-the-counter, and herbal products, as this medicine can interact with some of them. Do not take antacids that contain aluminum at the same time as this medicine, as they can reduce its absorption. If you have liver disease, your doctor may need to monitor your liver function regularly. Avoid drinking alcohol while taking this medicine, as it can increase the risk of liver problems. Do not drive or operate heavy machinery if you feel dizzy after taking this medicine. Keep this medicine out of the reach of children. Store it at room temperature, away from moisture and direct sunlight. Do not use this medicine after the expiry date printed on the pack.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine. Regular monitoring of liver and kidney function is recommended. Dose adjustment may be needed based on individual response.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, inform your surgeon and doctor that you are taking this medicine. It may need to be temporarily stopped before certain surgeries. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are usually needed, but your dentist may consult with your doctor if necessary.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce the risk of gallstones.
🥗
Eat a balanced diet low in saturated fats and cholesterol.
😴
Stay physically active with regular exercise like walking or swimming.
💧
Avoid alcohol consumption to protect your liver.
🧘
Drink plenty of water throughout the day.
🌞
Follow your doctor's advice for regular check-ups.

🏋️ Exercise Considerations

This medicine may cause dizziness in some people. Avoid strenuous exercise or operating heavy machinery if you feel dizzy. Otherwise, regular moderate exercise is encouraged as part of a healthy lifestyle.

🥗 Diet Recommendations

Include plenty of fruits, vegetables, and whole grains.
Choose lean proteins like fish, poultry, and beans.
Limit foods high in saturated fats and trans fats.
Avoid sugary drinks and processed foods.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to work. However, if you experience dizziness or fatigue, avoid driving or operating heavy machinery until you know how the medicine affects you.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Your doctor will determine when it is appropriate to stop based on your condition and response to treatment. If you experience serious side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored by a doctor. Regular liver function tests and ultrasound examinations may be required to monitor your condition and the medicine's effects. In some cases, prolonged use may lead to calcification of gallstones, which may require discontinuation. Always follow your doctor's advice regarding duration of treatment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Surgery (cholecystectomy)

Surgical removal of the gallbladder is a definitive treatment for symptomatic gallstones.

Evidence: Well-established
Extracorporeal shock wave lithotripsy

A non-invasive procedure that uses shock waves to break up gallstones.

Evidence: Moderate
Dietary modifications

A low-fat diet can help reduce symptoms of gallstones.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, continue taking your doses at the same intervals as prescribed. Check with the local embassy or customs about any restrictions on carrying prescription medicines. Always carry enough supply to last your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old woman with symptomatic gallstones who could not undergo surgery
She was prescribed this medicine to dissolve her gallstones. After 6 months of treatment, an ultrasound showed that her stones had reduced in size. She took the medicine regularly with meals and avoided fatty foods. She experienced mild nausea initially, which subsided after a few weeks.
💡 Lesson: Consistent use with food and dietary modifications can improve outcomes and tolerability.
👤 A 45-year-old man with primary biliary cholangitis
He started this medicine after being diagnosed with primary biliary cholangitis. His liver enzymes improved significantly within 3 months. He reported mild diarrhea initially, which was managed by taking the medicine with food. He continues to take it regularly and his liver function remains stable.
💡 Lesson: Regular monitoring and adherence to therapy are key to managing chronic liver conditions.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: For gallstone dissolution, it may take several months of continuous therapy. For liver conditions, improvement in liver enzymes may be seen within a few weeks.

Q: Can I take this medicine with food?

A: Yes, it is best taken with food to reduce stomach upset and improve absorption.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe during pregnancy?

A: It is classified as Pregnancy Category B. It should be used during pregnancy only if clearly needed, under medical supervision.

Q: Can I stop taking this medicine suddenly?

A: Do not stop taking this medicine without consulting your doctor, as it may worsen your condition.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ursolid 150 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken without a prescription.
    Fact: This medicine is a prescription drug and must only be taken under medical supervision.
  • Myth: This medicine can dissolve all types of gallstones.
    Fact: It is only effective for cholesterol gallstones that are small and not calcified.
  • Myth: This medicine is a painkiller.
    Fact: It is not a painkiller; it works by dissolving gallstones and improving liver function.

🔄 Alternative Options

Generic Alternatives

  • Ursodeoxycholic Acid 150 mg tablet

Brand Alternatives

  • Udiliv 150
  • Ursocol 150
  • Sorbidiol 150

📊 Comparison with Similar Medicines

[{"medicine":"Ursodeoxycholic Acid","class":"Bile acid","primary_use":"Gallstone dissolution, PBC","route":"Oral"},{"medicine":"Chenodeoxycholic acid","class":"Bile acid","primary_use":"Gallstone dissolution","route":"Oral"},{"medicine":"Obeticholic acid","class":"FXR agonist","primary_use":"Primary biliary cholangitis","route":"Oral"}]

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